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15 Cards in this Set

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  • Back

Mechanism Theophylline

competitive nonselective PDE inhibitor, nonselective adenosine receptor antagonist, restore depleted histone deacetylase, activate histone deacetylase 2

Mechanism Candesartan

ACE II receptor antagonist, Not ACE inhibitor. Latter is 1st line for congestive heart failure.

Uses Clomipramine

OCD, panic disorder, major depressive disorder chronic pain

Lofepramine

3rd gen TCA, less sleepy

Felodipine Mechanism & Specificity

Calcium channel blocker, vascular / cardiac: 12

Metaraminol

Potent sympathomimetics for hypotension especially anaesthesia related

Alfentanil

Short-acting potent anaesthetic, less potent & durable than fentanyl but faster onset

Buprenorphine

Long-acting strong opioid, treats moderate pain and addiction

adenosine different actions on muscles

contract heart muscles but relax smooth muscles

relationship between caffeine and Theophylline

liver process caffeine can produce Theophylline, they have chemical similarity

Risperidone mechanism and uses

Antagonist for 5-HT 2A/2C, dopamine 1-5. More affinity to 5-HT. Dopamine antagonist is anti-psychotic w/ low risk of EPS. 5-HT 2A is also linked to anti-psychotic effects and relief of EPS. Use in schizophrenia, bipolar, irritability in autism

Venlafaxine mechanism uses

5-HT and Norepinephrine reuptake inhibitor (SNRI), major depression, generalized anxiety disorder, panic disorder, social phobia

Adalimumab mechanism, uses, route

binds to TNF-alpha instead of receptor. RA, psoriatic arthritis, idiopathic juvenile arthritis, Crohn's disease ulcerative colitis, alkylosing spondylitis, chronic psoriasis. Subcutaneous, biweekly for maintenance

Tizanidine

antispasmodic for multiple sclerosis snd cerebral palsy

Tranexamic acid

Tx or prevent excessive blood loss in trauma, menstrual disorder, hemophilia, OT with bleeding risk, and angioedema