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15 Cards in this Set
- Front
- Back
Mechanism Theophylline |
competitive nonselective PDE inhibitor, nonselective adenosine receptor antagonist, restore depleted histone deacetylase, activate histone deacetylase 2 |
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Mechanism Candesartan |
ACE II receptor antagonist, Not ACE inhibitor. Latter is 1st line for congestive heart failure. |
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Uses Clomipramine |
OCD, panic disorder, major depressive disorder chronic pain |
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Lofepramine |
3rd gen TCA, less sleepy |
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Felodipine Mechanism & Specificity |
Calcium channel blocker, vascular / cardiac: 12 |
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Metaraminol |
Potent sympathomimetics for hypotension especially anaesthesia related |
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Alfentanil |
Short-acting potent anaesthetic, less potent & durable than fentanyl but faster onset |
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Buprenorphine |
Long-acting strong opioid, treats moderate pain and addiction |
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adenosine different actions on muscles |
contract heart muscles but relax smooth muscles |
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relationship between caffeine and Theophylline |
liver process caffeine can produce Theophylline, they have chemical similarity |
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Risperidone mechanism and uses |
Antagonist for 5-HT 2A/2C, dopamine 1-5. More affinity to 5-HT. Dopamine antagonist is anti-psychotic w/ low risk of EPS. 5-HT 2A is also linked to anti-psychotic effects and relief of EPS. Use in schizophrenia, bipolar, irritability in autism |
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Venlafaxine mechanism uses |
5-HT and Norepinephrine reuptake inhibitor (SNRI), major depression, generalized anxiety disorder, panic disorder, social phobia |
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Adalimumab mechanism, uses, route |
binds to TNF-alpha instead of receptor. RA, psoriatic arthritis, idiopathic juvenile arthritis, Crohn's disease ulcerative colitis, alkylosing spondylitis, chronic psoriasis. Subcutaneous, biweekly for maintenance |
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Tizanidine |
antispasmodic for multiple sclerosis snd cerebral palsy |
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Tranexamic acid |
Tx or prevent excessive blood loss in trauma, menstrual disorder, hemophilia, OT with bleeding risk, and angioedema |