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38 Cards in this Set

  • Front
  • Back
Take them before you DINE
H2 blockers (Cimetidine, ranitidine, famotidine, nizatidine)
Use for ulcer, gastritis, mild esophageal reflux
H2 blockers (Cimetidine, ranitidine, famotidine, nizatidine)
Potent P-450 inhibitor
ANTIANDRONERGIC effects: prolactin release, gynecomastia, impotence, low libido in males)
Cimetidine
PPI
Omeprazole
PPI
Lansoprazole
Peptic ulcers, gastritis, esophageal reflux, Zollinger-Ellison syndrome
PPI (Omeprazole, Lansoprazole) MOA: irreversibly inhibit H/K-ATPase in stomach parietal cells
traveler's diarrhea and ulcer healing
Bismuth and Sucralfate
Tipple therapy for H.pylori ulcers
Metronidazole, Amoxicillin (or Tetracycline), Bismuth
Prevention of NSAID-induced peptic ulcers, maintenance of patent ductus arteriosus and to induce labor
Misoprostol (MOA: a PGE1 analog. Decreases acid production, increases production and secretion of gastric mucous barrier)
for Peptic ulcer (MOA: blocks M1(histamine secretions down) and M3 receptors on parietal cells (H+ secretion down)
Pirenzepine and Propantheline
SE of Antacid
hypoKalemia
Antacid Aluminum hydroxide SE
minimum mount of feces (constipation) :) proximal muscle weakness, osteodystrophy and seizures
Antacid Magnesium hydroxide SE
hyporeflexia and cardiac arrest
Antacid Calcium carbonate SE
rebound acid
Crohn's dx and Ulcerative colitis. Rx that is activated by colonic bacteria
Sulfasalazine (sulfa rx)
SE reversible oligospermia
Crohn's and RA. Rx that screws up a proinflammatory cytokine TNF
Infliximab

SE respiratory infection
Controls vomiting (you can go on dancing without vomiting:)) 5HT3 antagonist. Central acting antiemetic
ONDANSetron
Diabetic and post surgical gastroparesis
Metoclopramide
SE parkinsonian effects, depression
Interacts with digoxin and diabetic Rx
A lipid lowering agent whose SE is gallstones
Clofibrate
Rx that SE acute pancreatitis
Sulfa drugs
treat hereditory hemochromatosis
Deferoxamine and phlebotomy
Treat Wilson's dx with
Penicillamine
Nitrosamine exposure (also H.pylori, high salt intake) associated with?
carcinoma of the stomach
Acetaminophen OD (halothane and rifampin also)->?
Centrilobular necrosis immediately around hepatic vein. Diffuse hepatic necrosis also possible
Acute hepatitis caused by which rx?
INH (isoniazid), nitrofurantoi, phenytoin. Acetaminophen is not associated with acute hep
Salicylates, ethanol, tetracycline may cause?
Fatty change in liver
Heroin and other opiates stimulate which receptors of brain and GI tract?
mue (m) pleasure sensation, decreased bowel motility. I.e. do not give opiates to pnts with bowel obstruction!
Procainamide and hydralazine
Drug induced Lupus!
Which rx can cause a drug induced SLE?
Procainamide and hydralazine
PCP (Phencyclidine)
inhibits depolarization of neurons and interferes with cognitive and other functions of the nervous system. Management-supportive care
Antidode to anticholinergics when pnt ODed and looks like blind as a bat, hot as Hades, etc
Physostigmine (AChAse inhibitor) that way Cholinergic activity is regained...
all our locals love Jimson Weed!
besides anti-cholinergic, massive hallucinations
Methanol (wood alcohol) toxicity
Alcohol dehydrogenase makes formic acid-TOXIC like a mother. Putamen hemorrhage on CT. Necrosis. Give EtOH to overwhelm dehydrogenase. Toxic to optic n (CNII)
Stimulants: cocaine, amphetamine, theophylline, caffeine, hallucinogens, early effect of TCA
tremor, agitation, mydriasis, tachycardia
diaphoretic, manic, seizures, hyperthermia
manage cocaine OD
benzo
Anticholinergics
atropine, TCAs, phenothiazines
belladonna, antihistamines
Cholinergics:
PRIMARY: bethanocol, mushrooms
Cholinesterase inhibitors: nerve agents, carbamates, organophosphate insecticides
OD on aspirin (salicilates) s&s:
altered mental status, tinnitus, seizures; noncardiogenic pulmonary edema;