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18 Cards in this Set

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7 Ps of Rapid Sequence Intubation (RSI)
Preparation,
Pre‐oxygenation,
Pretreatment (100% O2 for 3 mins via NRBR Mask)
Paralysis and induction,
Position,
Placement with proof,
Postintubation management
Any contraindications to RSI?
All are relative.

Only case would be if paralysis led to a "cant intubate can't ventilate" situation.
What are the adverse effects of laryngoscopy in adults and children?
Adults: relfex sympathetic response = increase of BP + HR. (bad if pt has increase ICP, MI, aortic dissection)

Children: vagal bradycardic response.
What are the common pre-treatment agents with their respective doses?
Fentanyl: 3 mg / kg IV push over 30-60 sec.

Lidocaine: 1.5 mg / kg IV

Atropine: 0.02 mg / kg IV (children)
0.01 mg / kg IV (adults)
What are the indications and caveats for Lidocaine?
I: equivocal evidence for raised ICP and bronchospasm/asthma

caveats: NO evidence of improved outcomes
What are the indications and caveats for Fentanyl?
Ind: to blunt sympathetic response of laryngoscopy (where raised HR, BP, ICP would be harmful to the pt.)

Cav: can cause hypotension +/- resp. depression when not given in suggested dose or time frame.
What are the indications and caveats for Atropine?
Ind: children < 5 yo WITH bradycardia
children < 10 yo. receving succ. WITH bradyC
adults with bradyC after repeat doses of succs

Cav: doesn't consistently prevent bradyC.
Three induction agents for RSI?

What are their doses of each?
Propofol: 0,5-1.5 mg / kg IV. Induction in 30 sec.
(lasts ~10 mins)

Ketamine: 1-2 mg / kg IV. induction in 1 min
(lasts 10-20 mins)

Etomidate: 0.3 mg / kg IV. induction in <1 min.
(lasts 10-20 mins)
What is a simple way of remembering these doses?
Think 2's

Prop: 2 mg / kg

Ketamine 2 mg / kg

Etomidate 0,2 mg / kg
When should you use etomidate?
Ind: hemodynically stable (when ICP and Cardiac stability are needed).

Note: can cause severe myoclonic jerks (give ample benzo or narcotic); not analgesic

Caveats: theoretical concerns of cortisol inhibition (esp. septic patients)
When is propofol used for induction?
Ind: "quick on quick off". Use when you want to lower ICP. Has anticonvulsant and antiemetic properties.

Caveats: can cause hypotension, and apnea. NOT analgesic
What are indications and caveats for ketamine?
Ind: Good for the head injured hypotensive patient
PRESERVES respiratory drive.
Has antiemetic, amnesic, bronchodilator properties.

Caveats: not recommended for the elderly or those with cardiac ischemia (due to refractory tachyC/HTN).
Two most common paralytics?

Doses?
Succinylcholine. 1.5 mg / kg. (onset 45-60 sec).
5-10 min duration.

Rocuronium. 1 mg / kg. (1-3 min onset).
30-45 min duration.
Why use paralytics in RSI?
1. assist tracheal intubation
2. aid mechanical ventilation
3. control ICP (avoid intracranial HTN)
Why is succinylcholine the preferred agent for RSI?
quick on quick off (<1 min on, <10 min off)
What are the relative contraindications to using succinylcholine?
1. hyperkalemic patients (succ. causes a ~0.5 mEq/L rise in serum K+)
> burns, crush, infections GREATER than 5 days old
2. pseuocholinesterase deficiencies ; myasthenia gravis.
3. cocaine or amphetamine abusers
What are the indications and caveats of rocuronium?
Ind: when a contraindication to succinylcholine is anticipated,

Caveats: longer duration of action (30-45 mins). Can cause tachycardia. Longer onset of action (1-3 mins).
What induction agent is preferred for the head-injured patient?

For the major trauma patient?
Ketamine is thought to be cerebroprotective and optimal for the head injured patient.

Etomidate's hemodynamic stability makes it ideal for major traumas.