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30 Cards in this Set

  • Front
  • Back
Bias introduced into a study when a clinician is aware of the patient's treatment type.
Observational bias
Bias introduced when screening detects a disease earlier & thus lengthens the time from diagnosis to death.
Lead-time bias
If you want to know if race affects infant mortality rate but most of the variation in infant mortality is predicted by socioeconomic status, then socioeconomic status is a ____.
confounding variable
The number of true positives divided by the number of patients w/ the disease is ____.
sensitivity
Sensitive tests have few false negatives & are used to rule ____ a disease.
OUT
PPD reactivity is used as a screening test because most people w/ TB (except those who are anergic) will have a (+)PPD. Highly sensistive or specific?
highly SENSITIVE for TB
Chronic diseases such as SLE -- higher prevalence or incidence?
higher PREVALENCE
Epidemics such as influenza -- higher prevalence or incidence?
higher INCIDENCE
Cross-sectional survey --incidence or prevalence?
PREVALENCE
Cohort study -- incidence or prevalence?
incidence AND prevalence
Case-control study -- incidence or prevalence?
Neither
Describe a test that consistently gives identical results, but the results are wrong.
high reliability, low validity
Difference between a cohort & a case-control study.
COHORT studies can be used to calculate relative risk (RR), incidence, and/or odds ratio (OR).
CASE-CONTROL studies can be used to calculate (only?) an odds ratio (OR).
Attributable risk?
[the incidence rate (IR) of a disease in exposed]
- [the IR of a disease UNexposed]
Relative risk?
[the incidence ratio (IR) of a disease in a population exposed TO A PARTICULAR FACTOR] / [the IR of those not exposed]
Odds ratio (OR)?
The liklihood of a disease among individuals exposed to a risk factor compared to those who have NOT been exposed
Number needed to treat (NNT)?
1 / [rate in UNtreated - rate in treated group]
In which patients do you initiate colorectal cancer screening early?
Patients who have either ...
IBD
FAP/HNPCC;
1st-degree relatives w/ adenomatous polyps (<60 y/o), or colorectal cancer
The most common cancer in men & the most common cause of death from cancer in men.
PROSTATE cancer is the most common cancer in men, but LUNG cancer causes more (the most) deaths
The percentage of cases within ONE standard deviation (SD) from the mean?
TWO SDs?
THREE SDs?
1 SD = 68.0%
2 SD = 95.5%
3 SD = 99.7%
Birth rate?
Number of live births per 1000 population
Fertility rate?
Number of live births per 1000 WOMEN 15-44 YEARS OF AGE
Mortality rate?
Number of deaths per 1000 population
NEONATAL mortality rate?
Number of deaths from
*BIRTH - 28 DAYS*
per 1000 LIVE births
POSTNATAL mortality rate?
Number of deaths from
*28 DAYS - 1 YEAR*
per 1000 LIVE births
INFANT mortality rate?
Number of deaths from
*BIRTH - 1 YEAR*
per 1000 LIVE births

(neonatal mortality + postnatal mortality)
FETAL mortality rate?
Number of deaths from
*20 WEEKS GESTATION - BIRTH*
per 1000 TOTAL births
PERINATAL mortality rate?
Number of deaths from
*20 WEEKS GESTATION - 1 MONTH OF LIFE*
per 1000 TOTAL births
MATERNAL mortality rate?
Number of deaths
*DURING PREGNANCY - 90 DAYS POSTPARTUM*
per 1000 LIVE births
X (type) mortality rate = number of deaths from [A - B] timeframe per 1000 [LIVE, TOTAL] deaths

(neonatal, postnatal, infant, fetal, perinatal, maternal)
NEONATAL: birth - 28 days (live)
POSTNATAL: 28 days - 1 year (live)
INFANT: birth - 1 year (live)

FETAL: 20 weeks' gestation - birth (total)
PERINATAL: 20 weeks' gestation - 1 month of life (total)

MATERNAL: during pregnancy - 90 days postpartum (live)