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51 Cards in this Set

  • Front
  • Back

When did sleep research begin?

early and mid 20th century
What did early sleep research study?
Sleep Stages
Sleep disorders
All night recording
When was polysomnography first used?
1974
What does "Poly" mean in polysomnography?
recording of different parameters (many)
What does "Somno" mean in polysomnography?
relating to sleep
What does "Graphy" mean in polysomnography?
charting of parameters
What is recorded during PSGs?
-EEG (brain wave activity)
-EOG (eye movement)
-EMG (muscle activity)
-Airflow
-Respiratory Activity (chest and abdomen)
-EKG (Heart Rate and Rhythm)
-SaO2- (Blood Oxygen Saturation)
-CO2 (end tidal or transcutaneous CO2)
When was the Association for PSG Techs (APT) founded?
1978
When and where was the first narcolepsy clinic opened?
1964 at Stanford University
When does the Stanford clinic expand to include all sleep disorders?
1970
By 1975 how many other sleep disorders centers are operating?
5
When does Blue Cross/Shield of California begin reimbursing for sleep studies?
1975
What sleep center, and when, was the first accredited?
Montifore Hospital in New York, 1977
When was the first board exam for sleep medicine and what was it called?
1978, Diplomate, America Board of Sleep Medicine
When was the first sleep fellowship training established?
1989
What is the purpose of the AASM (American Association for Sleep Medicine)?
-establish standard research, evaluation and treatment
-Professional: serves needs of members, centers, and labs
-establish practice parameters
-2 Journals: SLEEP, Journal of Clinical Sleep Medicine
When was the "AASM Manual for Scoring Sleep" created?
2007
When was NREM sleep established
1937
Who developed the class system for brain wave activity?
Alfred Lee Loomis
What were the classifications Loomis created?
-vertex waves
-spindles
-K-complexes
-Delta slowing
-5 stages: A, B, C, D, E
When was Rapid Eye Movement (REM) Sleep Established?
1953
Who wrote the 1st paper describing REM sleep?
Eugene Aserinsky and Nathaniel Kleitman
Who described the sleep cycle of NREM stages?
William Dement and Nathaniel Kleitman
How did Dement and Kleitman describe the sleep cycle of NREM?
As stages of NREM of increased depths followed by periods of REM with cycles repeating
What new class of stages did Dement and Kleitman propose?
4 NREM and REM
When the Rechtschaffen and Kales "Manual for Standardized Terms, Tech, and Scoring System for Sleep Stages for Human Subjects" created?
1968, 1st manual for sleep and a research tool
What is the average normal human sleep needed (young adults)
7.5-8.5 hours
What is the average normal sleep latency?
10 minutes
What is the average normal percent of time spent in Stage N1 sleep?
2-5%
What is the avg normal percent of time spent in Stage N2 sleep?
45-55%
What is the avg normal percent of time spent in Stage N3 sleep?
13-22%
What is the avg normal percent of time spent in REM sleep
20-25%
How is sleep normally entered?
Through NREM
On average, how often do episodes of NREM and REM sleep alternate?
90-110 minutes
In what part of the night is REM more prominent?
2nd half of the night
What are stages of NREM sleep?
Stage N1
Stage N2
Stage N3
What percentage does NREM sleep make up in the sleep of older children and adults?
75-80%
What are the characteristics of REM sleep?
-20-25% of sleep
-4-6 discrete cycles through out the night
-longer cycles across the night
-longest cycle in last 1/3rd of the night
-linked to circadian rhythms and body temp
What are the Physiological Variables of NREM sleep:
-Heart Rate: Regular
-Respiratory Rate: Regular
-Blood Pressure: Regular
-Skeletal Muscle Tone: Preserved
What are the Physiological Variables of REM sleep?
-Heart Rate: Irregular
-Respiratory Rate: Irregular
-Blood Pressure: Irregular
-Skeletal Muscle Tone: Absent
How are brain wave frequencies measured?
Hertz (Hz): the number of waves or cycles per second
What is the frequency (Hz) of alpha waves?
8-13 Hz
What is the frequency (Hz) of theta waves?
4-7.9 Hz
What is the frequency (Hz) of delta waves?
0.5-3.9 Hz
What is the frequency (Hz) of beta waves?
>13Hz
What are the characteristics and scoring criteria for Stage Wake?
1) Alpha with eyes cloed over occipital region >50% of epoch
2) Without alpha
-eye blinking 0.5-2Hz
-Reading Eye Movements
-Irregular conjugate eye movements associated with normal or high chin muscle tone
What are the characteristics and scoring criteria for Stage N1?
-represents sleep onset
-may follow arousal from any stage
-EEG- low voltage, mixed frequency, theta of 4-7 Hz
->50% of epoch
-Slow eye movements
-EMG- relatively elevated, may decrease from wake
-2-5% of total sleep time (TST)
What are the characteristics and scoring criteria for Stage N2?
-1 or more spindles (11-16Hz, >0.5 sec)
-K-complexes
-low voltage mixed frequency background
-no eye movement
-EMG still relatively elevated
-45-55% of TST
What are the characteristics and scoring criteria for Stage N3?
-High amplitude (>75 microvolts) slow waves (0.5-2Hz)
-20% of epochs
-spindles may persist
-eye movements usually absent
-EMG: lower than N2, may be equal to REM
-13-22% of TST
What sleep disorders usually arise from Stage N3 (Slow Wave) sleep?
sleep walking, sleep terrors, and confusional arousals.
What are the characteristics and scoring criteria for Stage REM?
EEG- low voltage mixed frequency
-may see saw tooth waves
EMG- chin lower than any other stage, usually lowest level of recording
-Phasic activity: short bursts of muscle activity during REMs
-Tonic activity- periods of little muscle activity
-20-25% of TST
-4-6 cycles