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37 Cards in this Set

  • Front
  • Back
what is type 1 diabetes?
result of autoimmunity of beta cells of the pancreas resulting in absolute insulin deficiency and is managed with insulin
what is type 2 diabetes?
insulin resistance and inadequate insulin production. most prevalent, can be controlled with diet, exercise and oral glycemic agents.
is oral hypoglycemic agents preferred in pregnant women?
no
how is diabetes characterized in pregnancy
pregestational diabetes (1 or 2)
gestational diabetes
during pregnancy the body is in a state of insulin resistance, is this pathological or physiological?
physiological- it is to spare glucose for the developing fetus
what is the hormones that the placenta produces to antagonize insulin?
Human placental lactogen
progesterone
growth hormone
corticotropin- releasing hormone
how does a normal pregnant women maintain euglycemia when there is increasing insulin resistance?
produce even more insulin
what are the management strategies for preexisting or gestational diabetes?
maintain euglycemia control
minimize complications
prevent prematurity
in the first trimester are insulin needs high or low?
low- at the end of the first trimester insulin requirements begin to rise as glucose use and glycogen storage by mother and fetus increase
what hormone causes resistance to the action of maternal insulin there by increasing circulating glucose for fetal use and increasing the demand on the maternal pancreas to produce more insulin?
human placental lactogen (hPL)
does the fetus produce its own insulin?
yes, but it obtains its glucose from the mother across the placenta.
t/f the amount of glucose available in maternal circulation stimulates the fetal pancreas to produce more insulin
true
what are some major risks for the women with DM in pregnancy?
DKA
HTN/preeclampsia
PTL
spontaneous abortions
polydydramnios/ oligohydramnios
c-section
retinopathy,nephropathy, neruopathy
infection r/t hyperglycemia
what are the major risks for the fetus when the mother has DM
hypoglycemia r/t fetal hyperinsulinemia
hypocalcemia and hypomagnesemia
asphyxia r/t hyperglycemai/hyperinsulinemia
RDS
hyperbilirubinemia congential defects
cardiomyopathy
macrosomia
what is macrosomia and why is it dangerous?
large body over 4500g puts the fetus at risk for trauma
why would a fetus be macrosomia if the mother has DM?
the excessive glucose that the mother is giving to the fetus acts as a growth hormone and produces a larger than normal fetus
what is the most important self-management of DM
SMBG- 4-8 times a day
what is the expected glucose in a fasting pt?
<95
what is the expected glucose in a premeal pt?
<105
what is the expected glucose in a 1 hr postprandial pt? (after a meal)
<140
what is the expected 2 h postprandial in a pt?
<120
what do large amounts of ketones in the urine indicate?
poor nutrition/inadequate food intake, sign of ketoacidosis
should the pt keep a record of diet, BS, insulin, and activity?
yes
how many times a week should a pt with diabetes exercise?
3 times a week for at least 20 min, unless contraindicated
t/f infants of diabetic women have an increased risk for respiratory distress syndrome( RDS)?
true- it is related to glycemic control
what test would you use to check for fetal lung development and RDS?
amniocentesis
do insulin requirements change with gestation?
yes, around 24-28 weeks gestation the requirements increase
what are s/s of hypoglycemia?
diaphoresis
tachy
cold clammy
blurred vision
extreme fatigue
altered LOC
somnolence and pallor
what can you use to treat hypoglycemia?
10-15g of carbs, it can raise your glucose by 30-40 mg/dl in 30 min
what are s/s of ketoacidosis
abd pain
n/v
polyuria
polydipsia
fruity breath
rapid respers
when should you instruct your pt with DM to call the dr?
BS >than 200
moderate ketones in urine
persistant n/v
decreased fetal movement
why is there an increase risk for DM's to have a stillbirth?
DM causes premature placental aging
should phosphatidyglycerol be present in amniotic fluid?
yes-Phosphatidylglycerol (PG) in amniotic fluid is recognized as a good indicator of fetal lung maturity
when preforming a GTT at 24 weeks, what is considered an abnormal finding?
a glucose of 130-140 mg/dl (depends on the dr)
what is done if a women who test positive on a GTT?
a 3 hour GTT is done with 100 grams of a glucose load.
how is a 3 hour GTT done?
100 grams of glucose is introduced and blood is drawn at 1(should be <180),2(should be <155) , and 3 hours(should be less than 140mg/dl)
what risk does gestational diabetes have on a pregnant women after she gives birth?
she will be at greater risk for developing type 2 diabetes