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85 Cards in this Set
- Front
- Back
Integration
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The process (located mainly in the CNS) of processing sensory input
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CNS
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Central Nervous System - the brain and spinal column
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PNS
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Peripheral Nervous System - spinal and cranial nerves
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Motor / Efferent Division
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Section of PNS that carries impulses to SNS or ANS
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SNS
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Somatic Nervous System - a division of the efferent portion of the PNS that carries impulses toward skeletal muscles for conscious action
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ANS
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Autonomous Nervous System - a division of the efferent portion of the PNS that automatically regulates organs, cardiac muscles and glands
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Parasympathetic Division of PNS
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Attempts to conserve energy and restore energy to body when at rest
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Sympathetic Division of PNS
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Causes actions in autonomic nerves - the continued pumping of the heart, eg.
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Neuroglia
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Smaller cells that Neurons associate with for supportive scaffolding and other functions. They include Microglia, ependymal cells,
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Astrocytes
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Most abundant CNS glial, act as basic connective tissue (transferring impulses, chemicals, and participate in thinking)
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Microglia
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CNS glial cell -
small ovoid cells that touch neurons to inspect their health. when a neuron is particularly injured or dead, or if they find alien particles, they bunch around it and eventually form special macrophages that phagocytizes the object. |
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Ependymal cell
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CNS glial cell -
cilia facilitate the flow of CSP in cavities- Varied in shape, usually ciliated - line the central cavities of brain/spine to make a barrier between tissue and CSP |
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Oligodendrocytes
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CNS glial cell -
Primarily Myelin Sheaths - branch (as do astrocytes) but mainly wrap around thicker neuron fibers forming insulated coverings |
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Schwann (aka neurolemmocytes)
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PNS glial cell-
surround nerve fibers, similar to oligodendrocytes |
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Satellite Cells
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PNS glial cells -
Controls extracellular fluid environment around neurons similarly to astrocytes of the CNS |
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Which two types of neuroglia controls the extracellular fluid environment around neuron cell bodies in the CNS? PNS?
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CNS: Astrocytes
PNS: Satellite Cells |
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What two types of neuroglia form insulating coverings called myelin sheaths?
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CNS: Oligodendrocytes
PNS: Schwann Cells |
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What is "Integration" and where does it occur?
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Integration is the processing of input signal, ergo it occurs in the brain (CNS).
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Which subdivision of the PNS is involved in:
1. relaying the full feeling in your stomach 2. contracting your arm muscles 3. increasing your heart rate |
1. PNS: Afferent
2. PNS: Efferent: Somatic 3. PNS: Efferent: ANS: Sympathetic |
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Major biosynthetic center of a neuron containing usual cellular organelles
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Cell body / soma / perikaryon
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Nissl Bodies / chromatophilic substance
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A nerve cell's rough endoplasmic reticulum
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Microtubules and neurofibrils
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Maintain the shape and structure of the nerve cells
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Axon / Axon Hillock
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Axon - impulse generating and conducting region
Axon Hillock - internal area of axon interfacing with cell body |
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Axon Terminals
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The end of the Axon
- secretory region |
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Direction of impulses in a nerve cell
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From the dendrites toward the axon terminals
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Dendrites
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extensions of the cell body of a neuron that extend out to receive impulses
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Axon collaterals
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Axon branches extending from another axon at ~90 degree angles; these are usually at the end of the parent axon and are what comprise axon terminals
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Myelin sheaths
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Made of glial cells - Conduct impulses rapidly, hastening the signals' travel
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Axolemma
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The neuron's plasma membrane
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Nodes of Ravier / myelin sheath gaps
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Gaps in the length of the myelin sheath (~1 mm apart)
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Gray Matter
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matter containing mostly nerve cell bodies and unmyelinated fibers
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White Matter
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dense collections of myelinated fibers
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Which part of the neuron is its fiber?
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The axon
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How does nerve fibers differ from the fibers of connective tissue?
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In connective tissue fibers are elongated proteins cells, whereas in neurons the fibers are an organelle of a cell.
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How is a nucleus within the brain different from a nucleus within a neuron?
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The nucleus in the brain is shared between a cluster of cell bodies whereas in the neurons they act as the control center for its cell.
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How is a myelin sheath formed in the CNS and what is its function?
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In the CNS it is formed by oligodendrocytes that wrap the axons with their plasma membranes.
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Structural classification of Neurons
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Multipolar (99% of neurons, major type in CNS)
Bipolar (rare, found in eyes) Unipolar (Common only in dorsal root ganglia and sensory ganglia of cranial nerves) |
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Structural classification of Neurons
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Motor / Efferent
Sensory / Afferent Interneurons / Association |
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When you burn your finger, what nerve is activated first?
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unipolar sensory/afferent neurons
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When you burn your finger, what is the last nerve
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multipolar motor/efferent neurons
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Chemically / Ligand gated channels
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when appropriate chemicals are present
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voltage gated channels
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changes in the membrane potential
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mechanically gated channels
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sensory receptors for pressure/ touch
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Ohm's Law
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Current = Voltage / Resistance
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Depolarization
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a reduction in the membrane potential
the inside of the membrane loses electrons |
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Hyperpolarization
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an increase in the membrane potential
The inside of the membrane gains electrons |
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Graded potentials
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short lived localized changes in membrane potential that can be either depolarizations or hyperpolarizations
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AP ("nerve impulse" in neuron)
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Action Potential
a brief reversal of membrane potential with a total amplitude of ~100mV |
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Absolute Refractory Period
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The time from the initial opening of the Na+ channels to their first closin
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Relative refractory period
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The time after an AP when the threshold is much higher since there is still a tendency toward equilibrium on the membrane --
doing anything is possible, but more demanding |
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synaptic cleft / gap junction
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The separation space between neurons at a synapse.
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EPSP
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Excitatory postsynaptic potentials -
the graded imbalance that creates a reaction from the postsynaptic membrane. Allowance of K+ and Na+ ions to pass through the membranes results in a net imbalance of potential |
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ISPS
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Inhibitory Postsynaptic Potentials
The refractive period that ensures that, once a synapse has fired, as it's returning to equilibrium it is less likely to fire. Allowance of K+ and Cl- ions to move through membranes |
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EPSP Summation
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Temporal Summation
- when one or more presynaptic neuron triggers (basically the postsynaptic membrane doesn't have the time to recover between firings) Spatial Summation - Neurons from a small area all fire once and their shared potential triggers the postsynaptic membrane |
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Facilitated neurons
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Neurons whose postsynaptic membrane is nearing (but not yet at) the point of triggering a potential
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Synaptic Potentiation
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The ability of a synapse to respond to stimulus over time by becoming more responsive to it - like trepps for muscles
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Presynaptic inhibition
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When the presynaptic neuron prevents releases less chemicals in response to an impulse than it would without interference
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Classifying Neurotransmitters: Chemically
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Acetylcholine - degraded by acetylcholinesterase, found at neuromuscular junctures
Biogenic Amines - mainly in the brain has to do with sleep scheduling and mood. serotonin. Amino Acids - difficult to divine the general rule because of the common nature of amino acids. Peptides - endorphins acting as natural opiates and reducing our perception of pain Purines - Gases and Lipids - |
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Classifying Neurotransmitters: Functionally
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Effects: Excitatory vs Inhibitory
Actions: Direct vs Indirect |
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Neural Plate
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Weeks 1-4 in the formation of the embryo, the neural plate is all there is of the brain
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Neural tube
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Developed by week 4 of embryonic development, second significant stage of embryonic brain
(formed by the Neural Plate developing folds which then crest and join to make a tube) |
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Primary brain vesicles
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Formed from the neural tube, these divide the brain into developmental regions:
Prosencephalon - forebrain Mesencephalon - midbrain Rhombencephalon - hindbrain |
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Prosencephalon (forebrain)
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Divides into smaller sections in week 5:
telencephalon ("endbrain") diencephalon ("interbrain") |
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Mesencephalon (midbrain)
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Remain undivided, known as the cerebral aquaduct
contains the brain stem and midbrain |
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Rhombencephalon (hindbrain)
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Divides into smaller sections in week 5:
metencephalon ("afterbrain") myelencephalon ("spinal brain") |
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Telencephalon ("endbrain")
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Forms the lateral ventricles
Cerebrum: cerebral cortex, white matter, basal nuclei |
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Diencephalon ("interbrain")
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Forms the Third Ventricle
Thalamus, hypothalamus, epithalamus, retina |
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Metencephalon ("afterbrain")
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Forms the Fourth Ventricle with Myelencephalon
Pons, Cerebellum |
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Myelencephalon ("spinal brain")
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Forms the Fourth Ventricle with Metencephalon
medulla oblongata |
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Which ventricle is surrounded by the diencephalon?
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The Third Ventricle
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Brodmann areas
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The 52 areas of the brain identified by
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Primary Motor cortex (motor)
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Allows control of voluntary movement around the body with pyramidal cells
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Pyramidal cells
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large neurons located in primary motor cortex gyri allow us to consciously control voluntary movements
Their axons comprise pyramidal tracts |
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Premotor cortex (motor)
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anterior to the frontal lobe, this region controls learned motor skills such as typing, drawing, and playing instruments. also this region is included in planning movement.
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Broca's Area (motor)
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anterior to the inferior region of the premotor area. Helps in speaking and planning speaking. This is usually found in only one of the hemispheres (usually left)
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Frontal eye field (motor)
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voluntary movement of the eyes, located anterior to the premotor cortex
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Primary somatosensory cortex (sensory)
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grants us spacial discrimination,
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Somatosensory association cortex
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temperature pressure etc
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name the components of the basal nuclei
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Caudate nucleus
putamen global pallidus |
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Basal Nuclei / Basal Ganglia ('Ganglia' is depreciated)
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the third basic region of each hemisphere, a grouping of subcortical nuclei.
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Cerebral white matter
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the second basic group of each cerebral hemisphere
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Commissures (made of Commissural fibers)
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connect corresponding gray areas of the two hemispheres
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Corpus Callosum
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largest commissure in brian
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association fibers
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connect different parts of the same hemisphere
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projection fibers
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either enter the cerebral cortex from lower brain or cord centers, or they descend from the cortex to lower areas.
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