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85 Cards in this Set

  • Front
  • Back
Integration
The process (located mainly in the CNS) of processing sensory input
CNS
Central Nervous System - the brain and spinal column
PNS
Peripheral Nervous System - spinal and cranial nerves
Motor / Efferent Division
Section of PNS that carries impulses to SNS or ANS
SNS
Somatic Nervous System - a division of the efferent portion of the PNS that carries impulses toward skeletal muscles for conscious action
ANS
Autonomous Nervous System - a division of the efferent portion of the PNS that automatically regulates organs, cardiac muscles and glands
Parasympathetic Division of PNS
Attempts to conserve energy and restore energy to body when at rest
Sympathetic Division of PNS
Causes actions in autonomic nerves - the continued pumping of the heart, eg.
Neuroglia
Smaller cells that Neurons associate with for supportive scaffolding and other functions. They include Microglia, ependymal cells,
Astrocytes
Most abundant CNS glial, act as basic connective tissue (transferring impulses, chemicals, and participate in thinking)
Microglia
CNS glial cell -
small ovoid cells that touch neurons to inspect their health. when a neuron is particularly injured or dead, or if they find alien particles, they bunch around it and eventually form special macrophages that phagocytizes the object.
Ependymal cell
CNS glial cell -
cilia facilitate the flow of CSP in cavities-
Varied in shape, usually ciliated - line the central cavities of brain/spine to make a barrier between tissue and CSP
Oligodendrocytes
CNS glial cell -
Primarily Myelin Sheaths -
branch (as do astrocytes) but mainly wrap around thicker neuron fibers forming insulated coverings
Schwann (aka neurolemmocytes)
PNS glial cell-
surround nerve fibers, similar to oligodendrocytes
Satellite Cells
PNS glial cells -
Controls extracellular fluid environment around neurons similarly to astrocytes of the CNS
Which two types of neuroglia controls the extracellular fluid environment around neuron cell bodies in the CNS? PNS?
CNS: Astrocytes
PNS: Satellite Cells
What two types of neuroglia form insulating coverings called myelin sheaths?
CNS: Oligodendrocytes
PNS: Schwann Cells
What is "Integration" and where does it occur?
Integration is the processing of input signal, ergo it occurs in the brain (CNS).
Which subdivision of the PNS is involved in:
1. relaying the full feeling in your stomach
2. contracting your arm muscles
3. increasing your heart rate
1. PNS: Afferent
2. PNS: Efferent: Somatic
3. PNS: Efferent: ANS: Sympathetic
Major biosynthetic center of a neuron containing usual cellular organelles
Cell body / soma / perikaryon
Nissl Bodies / chromatophilic substance
A nerve cell's rough endoplasmic reticulum
Microtubules and neurofibrils
Maintain the shape and structure of the nerve cells
Axon / Axon Hillock
Axon - impulse generating and conducting region
Axon Hillock - internal area of axon interfacing with cell body
Axon Terminals
The end of the Axon
- secretory region
Direction of impulses in a nerve cell
From the dendrites toward the axon terminals
Dendrites
extensions of the cell body of a neuron that extend out to receive impulses
Axon collaterals
Axon branches extending from another axon at ~90 degree angles; these are usually at the end of the parent axon and are what comprise axon terminals
Myelin sheaths
Made of glial cells - Conduct impulses rapidly, hastening the signals' travel
Axolemma
The neuron's plasma membrane
Nodes of Ravier / myelin sheath gaps
Gaps in the length of the myelin sheath (~1 mm apart)
Gray Matter
matter containing mostly nerve cell bodies and unmyelinated fibers
White Matter
dense collections of myelinated fibers
Which part of the neuron is its fiber?
The axon
How does nerve fibers differ from the fibers of connective tissue?
In connective tissue fibers are elongated proteins cells, whereas in neurons the fibers are an organelle of a cell.
How is a nucleus within the brain different from a nucleus within a neuron?
The nucleus in the brain is shared between a cluster of cell bodies whereas in the neurons they act as the control center for its cell.
How is a myelin sheath formed in the CNS and what is its function?
In the CNS it is formed by oligodendrocytes that wrap the axons with their plasma membranes.
Structural classification of Neurons
Multipolar (99% of neurons, major type in CNS)
Bipolar (rare, found in eyes)
Unipolar (Common only in dorsal root ganglia and sensory ganglia of cranial nerves)
Structural classification of Neurons
Motor / Efferent
Sensory / Afferent
Interneurons / Association
When you burn your finger, what nerve is activated first?
unipolar sensory/afferent neurons
When you burn your finger, what is the last nerve
multipolar motor/efferent neurons
Chemically / Ligand gated channels
when appropriate chemicals are present
voltage gated channels
changes in the membrane potential
mechanically gated channels
sensory receptors for pressure/ touch
Ohm's Law
Current = Voltage / Resistance
Depolarization
a reduction in the membrane potential

the inside of the membrane loses electrons
Hyperpolarization
an increase in the membrane potential

The inside of the membrane gains electrons
Graded potentials
short lived localized changes in membrane potential that can be either depolarizations or hyperpolarizations
AP ("nerve impulse" in neuron)
Action Potential

a brief reversal of membrane potential with a total amplitude of ~100mV
Absolute Refractory Period
The time from the initial opening of the Na+ channels to their first closin
Relative refractory period
The time after an AP when the threshold is much higher since there is still a tendency toward equilibrium on the membrane --

doing anything is possible, but more demanding
synaptic cleft / gap junction
The separation space between neurons at a synapse.
EPSP
Excitatory postsynaptic potentials -
the graded imbalance that creates a reaction from the postsynaptic membrane.

Allowance of K+ and Na+ ions to pass through the membranes results in a net imbalance of potential
ISPS
Inhibitory Postsynaptic Potentials

The refractive period that ensures that, once a synapse has fired, as it's returning to equilibrium it is less likely to fire.

Allowance of K+ and Cl- ions to move through membranes
EPSP Summation
Temporal Summation
- when one or more presynaptic neuron triggers (basically the postsynaptic membrane doesn't have the time to recover between firings)

Spatial Summation
- Neurons from a small area all fire once and their shared potential triggers the postsynaptic membrane
Facilitated neurons
Neurons whose postsynaptic membrane is nearing (but not yet at) the point of triggering a potential
Synaptic Potentiation
The ability of a synapse to respond to stimulus over time by becoming more responsive to it - like trepps for muscles
Presynaptic inhibition
When the presynaptic neuron prevents releases less chemicals in response to an impulse than it would without interference
Classifying Neurotransmitters: Chemically
Acetylcholine - degraded by acetylcholinesterase, found at neuromuscular junctures
Biogenic Amines - mainly in the brain has to do with sleep scheduling and mood. serotonin.
Amino Acids - difficult to divine the general rule because of the common nature of amino acids.
Peptides - endorphins acting as natural opiates and reducing our perception of pain
Purines -
Gases and Lipids -
Classifying Neurotransmitters: Functionally
Effects: Excitatory vs Inhibitory
Actions: Direct vs Indirect
Neural Plate
Weeks 1-4 in the formation of the embryo, the neural plate is all there is of the brain
Neural tube
Developed by week 4 of embryonic development, second significant stage of embryonic brain

(formed by the Neural Plate developing folds which then crest and join to make a tube)
Primary brain vesicles
Formed from the neural tube, these divide the brain into developmental regions:

Prosencephalon - forebrain
Mesencephalon - midbrain
Rhombencephalon - hindbrain
Prosencephalon (forebrain)
Divides into smaller sections in week 5:

telencephalon ("endbrain")
diencephalon ("interbrain")
Mesencephalon (midbrain)
Remain undivided, known as the cerebral aquaduct

contains the brain stem and midbrain
Rhombencephalon (hindbrain)
Divides into smaller sections in week 5:

metencephalon ("afterbrain")
myelencephalon ("spinal brain")
Telencephalon ("endbrain")
Forms the lateral ventricles

Cerebrum: cerebral cortex, white matter, basal nuclei
Diencephalon ("interbrain")
Forms the Third Ventricle

Thalamus, hypothalamus, epithalamus, retina
Metencephalon ("afterbrain")
Forms the Fourth Ventricle with Myelencephalon

Pons, Cerebellum
Myelencephalon ("spinal brain")
Forms the Fourth Ventricle with Metencephalon

medulla oblongata
Which ventricle is surrounded by the diencephalon?
The Third Ventricle
Brodmann areas
The 52 areas of the brain identified by
Primary Motor cortex (motor)
Allows control of voluntary movement around the body with pyramidal cells
Pyramidal cells
large neurons located in primary motor cortex gyri allow us to consciously control voluntary movements

Their axons comprise pyramidal tracts
Premotor cortex (motor)
anterior to the frontal lobe, this region controls learned motor skills such as typing, drawing, and playing instruments. also this region is included in planning movement.
Broca's Area (motor)
anterior to the inferior region of the premotor area. Helps in speaking and planning speaking. This is usually found in only one of the hemispheres (usually left)
Frontal eye field (motor)
voluntary movement of the eyes, located anterior to the premotor cortex
Primary somatosensory cortex (sensory)
grants us spacial discrimination,
Somatosensory association cortex
temperature pressure etc
name the components of the basal nuclei
Caudate nucleus
putamen
global pallidus
Basal Nuclei / Basal Ganglia ('Ganglia' is depreciated)
the third basic region of each hemisphere, a grouping of subcortical nuclei.
Cerebral white matter
the second basic group of each cerebral hemisphere
Commissures (made of Commissural fibers)
connect corresponding gray areas of the two hemispheres
Corpus Callosum
largest commissure in brian
association fibers
connect different parts of the same hemisphere
projection fibers
either enter the cerebral cortex from lower brain or cord centers, or they descend from the cortex to lower areas.