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29 Cards in this Set

  • Front
  • Back
what is primary prevention?
treating patients before they have the disease
at what age do the current recommendations say we should begin to intensively look at risk factors for atherosclerosis?
18 years old
what is secondary prevention?
treating patients when you know they already have the problem
which has a greater benefit from intervention: primary or secondary prevention?
secondary
what are the 3 non-modifiable risk factors associated with atherosclerosis?
- age
- sex (men > women)
- family history
why is family history difficult to assess?
because we learn our habits mostly from our parents so separating what is genetic and what is environment is difficult
what are the four main modifiable risk factors for atherosclerosis?
- smoking
- hypertension
- lipid abnormalities
- diabetes
what is the number one overall risk factor for developing atherosclerosis?
smoking
what determines the magnitude of risk?
- the amount of a given risk factor
- the number of risk factors
at what cholesterol level are you considered to have an average risk of a heart attack?
200
what are risk markers?
things to appear to be associated with the development of a disease but not causative
T or F: altering a risk marker appears to affect the progression or regression of a disease.
false; altering them does not have any affect on progression or regression
what are global risk scores used for?
to assess primary risk
what chance does a person with a high global risk score have of developing an cardiovascular event in the next 10 years? how should a physician proceed with these patients?
- > 20%

- treat them very aggressively as if they already have heart disease
what is the chance that a person with intermediate global risk score have of developing a cardiovascular event in the next 10 years? how should a physician proceed with these patients?
- 10-19%
- most likely need to begin medications in most cases
what is the chance of a person with a low global risk score having a cardiovascular event in the next 10 years? how should a physician proceed with these patients?
- < 10%
- concentrate on lifestyle changes and risk factor modification
what is primary prevention?
focuses on lifestyle and behavioral changes to prevent an event from occurrign
what is secondary prevention?
uses lifestyle and behavioral changes along with medications and medical intervention to prevent another event from occurring
what is the best thing a person can do to prevent atherosclerosis?
stop smoking
what is the biggest problem in treating atherosclerosis?
patient adherence to the treatment
what medications are the most commonly used and most effective in treating atherosclerosis?
LDL lowering medications
a 23 year old patient presents to your office for a physical. a CMP shows that the patient has very high LDL levels. you put them on a diet and a LDL lowering medication. they are very compliant with the prescribed treatment and stick with it. 2 years later they present to the ED and are diagnosed with having a heart attack. a CMP at that time show no improvement in LDL levels. what should you do next?
test them for LDL receptor abnormalities
T or F: you cannot have too high level of HDL.
false; HDL > 100 mg/dL may not be protective and may reflect HDL dysfunction
how do triglycerides affect atherosclerosis?
they make LDL more atherogenic
what is the definition of metabolic syndrome?
- abdominal obesity
- hypertension
- glucose intolerance
- lipid abnormalities
what does the macrovascular component of diabetes cause?
atherosclerotic complications
what does the microvascular component of diabetes cause?
kidney, vision, and nerve problems
what causes death in diabetics? what reduces the quality of life of diabetics?
- macrovascular component
- microvascular component
T or F: it is more important to control blood sugars in a diabetic than it is to control blood pressure, LDL, and other atherosclerotic risk factors.
false; controlling the atherosclerotic risk factors is most important. this is what saves people's lives