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20 Cards in this Set
- Front
- Back
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Sjogren's si/sx
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triad - keratoconjuctivitis sicca, xerostomia, arthritis
also, pancreatitis, fibrinous pericarditis |
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Sjogren's labs
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+ ANA, antiRo/antiLa abs, 70% RF +
a/w HLA-DR3 |
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Behcet's si/sx
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20 yo
oral/genital ulcers uveitis, arthritis, other derm dz |
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Dermatomyositis si/sx
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young kids, old peeps
symmetric weakness of prox. muscles (can see dysphonia/dysphagia) look for trouble getting out of chair. skininvolvement = heliotrope rash around eyes + periorbital edema |
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Dermatomyositis labs
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high ESR, high CPK, abnl EMG, muscle bx --> inflamm, +ANA
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Kawasaki's si/sx
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<5 yo
truncal rash, fever >104x(>5d), conjunctival injection, cervical LAD, strawberry tongue, skin desquam. --> coronary vessel vasculitis, aneurysms, MI |
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Kawasaki Tx
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NOT STEROIDS
aspirin + IVIG |
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Polyarteritis nodosa si/sx
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a/w hep B + cryoglobulinemia
fever, abd pain, weight loss, renal d/o, peripheral neuropathies. |
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Polyarteritis nodosa labs
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high ESR, leukocytosis, anemia, hemat/proteinuria. Bx of medium-sized vessels --> vasculitis
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Scleroderma si/sx
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C - calcinosis
R - raynaud's E - esophageal dysmotility S - sclerodactyly T- telangectasia heartburn, mask-like leathery facies. |
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Scleroderma labs
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+ANA
+anticentrome Abs = CREST +antitopoisomerase = scleroderma |
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What drugs can cause secondary SLE?
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procainamide
hydralazine dilantin (phenytoin) sulfanomide INH |
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What is the dx lab in secondary SLE?
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+antihistone Abs
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What are the dx labs in SLE?
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+ANA screen
+antiSm or anti-ds-DNA |
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What are other lab findings in SLE?
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false + for VDRL or RPR for syphilis
PTT falsely elevated (SLE actually thrombogenic) |
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Takayasu's arteritis si/sx
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East Asian women 15-30yo
"pulseless" in 1 or both arms. carotid involve --> neuro si, stroke CHF |
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Wegener's granulomatosis si/sx
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old peep
nose bleeds, nasal perforation, hemoptysis, dyspnea, hematuria, ARF |
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What's the diff between Wegener's and Goodpasture?
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Weg = old peep, +ANCA
Goodpasture = young peep, +antiglomerular ab |
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Polymyalgia Rheumatica si/sx
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Women >50yo
Pectoral and pelvic girdles, neck involvement a/w temporal arteritis |
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Polymyalgia Rheumatica labs
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Really high ESR
normal muscle biopsy/EMG |
