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17 Cards in this Set

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Hydrocortisone, prednisone, triamcinolone, dexamtasone, bleclomethasone are examples of what kind of drugs?
Glucocorticoid
Glucocorticoids decrease the production of ___ and ____
Leukotrienes and prostanglandins
To treat Addison's disease, inflammation, immune suppression, asthma, use ____
Glucocorticoids
An important side-effect of Glucocortioid usage is ____
Iatrogenic Cushing's Syndrome
Buffalo hump, moon facies, truncal obesity, muscles wasting, thin skin, easy bruisability, osteoporosis, adrenocortical atrophy, peptic ulcers characterize what syndrome?
Cushing's Syndrome
Which two drugs inhibit cGMP phosphodiesterase, leading to smooth muscle relaxation in the corpus cavernosum and penile erection?
Sildenafil and Verdenafil --they fill the penis
What class of drugs are used tto treat erectile dysfunction
cGMP phosphodiesterase Inhibitors
CGMP inibitors taken with ____have a high risk of liofe-threeatening hypotension
nitrates
Which drugs is a partial agonist of estrogen recpetors in the pituitary gland, stimulating increase in LH and FSH, which stimulates ovulation to treat infertility
clomiphene
Clomiphene's side effects include:
Hotflashes, ovarian enlargment, multiple simultaneous pregnancies, visual disturbances
What abortifacient is a competitite inhibitor of preogestins at progesterone recpetor and may lead to heavy menstrual-like bleeding?
Mifepristone (RU486)
The advantage of this drug is that it is reliable, decreases incidence of ectopic pregnancy, decreases risk of pelvic infections, and regulates menses; however it also puts you in a hypercoagulable stat and may increase your trigylcerides, weight, and blood pressure
Oral Contracpetices - syntheitc progestins/estrogen
____is converted to uric acid which leads to gout
Xanthine (converted from excess purines)
This drug depolymerizes microtubules, impairing leukocyte chemotaxis and degranulation, and used to treat acute gout
Colchicine
This drugs inhibits reabsorption of uric acid and used to treat chronic gout
Probenecid
This drug is used to treat chronic gout, but also inhbits secretion of penicillin
Probenecid
This drugs inhibits xanthine oxidase decreasing the conversion fo xanthine to uric acid
Allopurinol