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17 Cards in this Set
- Front
- Back
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Hydrocortisone, prednisone, triamcinolone, dexamtasone, bleclomethasone are examples of what kind of drugs?
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Glucocorticoid
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Glucocorticoids decrease the production of ___ and ____
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Leukotrienes and prostanglandins
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To treat Addison's disease, inflammation, immune suppression, asthma, use ____
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Glucocorticoids
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An important side-effect of Glucocortioid usage is ____
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Iatrogenic Cushing's Syndrome
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Buffalo hump, moon facies, truncal obesity, muscles wasting, thin skin, easy bruisability, osteoporosis, adrenocortical atrophy, peptic ulcers characterize what syndrome?
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Cushing's Syndrome
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Which two drugs inhibit cGMP phosphodiesterase, leading to smooth muscle relaxation in the corpus cavernosum and penile erection?
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Sildenafil and Verdenafil --they fill the penis
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What class of drugs are used tto treat erectile dysfunction
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cGMP phosphodiesterase Inhibitors
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CGMP inibitors taken with ____have a high risk of liofe-threeatening hypotension
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nitrates
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Which drugs is a partial agonist of estrogen recpetors in the pituitary gland, stimulating increase in LH and FSH, which stimulates ovulation to treat infertility
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clomiphene
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Clomiphene's side effects include:
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Hotflashes, ovarian enlargment, multiple simultaneous pregnancies, visual disturbances
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What abortifacient is a competitite inhibitor of preogestins at progesterone recpetor and may lead to heavy menstrual-like bleeding?
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Mifepristone (RU486)
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The advantage of this drug is that it is reliable, decreases incidence of ectopic pregnancy, decreases risk of pelvic infections, and regulates menses; however it also puts you in a hypercoagulable stat and may increase your trigylcerides, weight, and blood pressure
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Oral Contracpetices - syntheitc progestins/estrogen
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____is converted to uric acid which leads to gout
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Xanthine (converted from excess purines)
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This drug depolymerizes microtubules, impairing leukocyte chemotaxis and degranulation, and used to treat acute gout
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Colchicine
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This drugs inhibits reabsorption of uric acid and used to treat chronic gout
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Probenecid
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This drug is used to treat chronic gout, but also inhbits secretion of penicillin
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Probenecid
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This drugs inhibits xanthine oxidase decreasing the conversion fo xanthine to uric acid
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Allopurinol
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