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14 Cards in this Set
- Front
- Back
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What steroids come from the zona fasciculata?
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glucocorticoids
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What steroids come from the zona glomerulosa?
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mineralcorticoids
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Which steroids have anti-inflammatory, immunosuppressive, and metabolic actions?
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glucocorticoids
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What inhibits the immune system?
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Cortisol
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Cortisol
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Synthetic glucocorticoid
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Methylprednisolone
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Synthetic glucocorticoid
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Prednisone
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Synthetic glucocorticoid
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Triamcinolone
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Synthetic glucocorticoid
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Do corticosteroids inhibit both early and late stages of inflammation?
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YES
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How do glucocorticoids effect immune cells?
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-induce apoptosis
-reduce pro-inflammatory cytokines -increase anti-inflammatory cytokines |
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What cells do they induce apoptosis in?
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T cells & macrophages
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What is a potent transcription factor that stimulates gene expression of a number of proinflammatory cytokines?
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NFkB
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How long does it take to recover full adrenal function after been taken of steroids?
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2 months
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Opoids are agonist of what?
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G-protein linked opoid receptors (mu, delta, and kappa)
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