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17 Cards in this Set
- Front
- Back
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If bone pain occurs at night or during rest, what are some likely causes? (3) |
- Bone Tumor - Paget's disease - Fracture |
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If pain occurs during or after prolonged use of a joint and lack of use leaves it stiff, what is a likely diagnosis? |
osteoarthritis |
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If pain associated with a joint occurs during use and mostly in the morning, what is a likely diagnosis? |
Inflammatory or infective causation |
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What presentation makes rheumatoid arthritis stand out among other causes of joint pain? |
Symmetric presentation |
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How does ankylosing spondylitis differ from other causes of joint pain? |
Its effects are both centrally and peripherally distributed. |
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How does reactive arthritis pain differ from other causes of joint pain? |
Dactylitis can occur. |
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What are methods of rehabilitation for joint related problems? (6) |
- Pain control (thermal or electric stimulation) - Range of motion - Muscle strength - Aerobic capacity - Balance and agility - Pain-related fear |
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What can be used to apply heat to a joint? (3) |
- hot pack - paraffin - hot tub |
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What can be used to apply cold to a joint? (4) |
- Cryocuff - Ice pack - Frozen vegetables - Ziploc bag with ice+alcohol |
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Name 4 disease modifying anti-rheumatic drugs. |
- Chloroquine - Sulfasalazine - Methotrexate - Leflunomide |
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Name 4 immunosuppressive drugs for rheumatic diseases. |
- Azathioprine - Cyclophosphamide - Mycophenylate mofetil - Calcineurin inhibitors |
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What drug co-stimulates T-cells for treatment of rheumatic disorders? |
Abatacept |
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What drugs deplete B-cells for rheumatic disorder treatment? (2) |
- Rituximab - Belimumab |
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What are three IL-1 inhibitors for treatment of rheumatic disorders? |
- Anakinra (antagonist) - Rilonacept (decoy) - Canakinumab (anti-IL1 Ig) |
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Name 5 inhibitors of tumor necrosis factor. (5) |
- Etanercept - Adalimumab - Infliximab - Certolizumab - Golimumab |
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Name a rheumatic disorder drug that inhibits tyrosine kinase. |
Tofacitinib |
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What must be managed pharmacologically for rheumatoid patients? (7) |
- Infections - Pregnancy - Neoplasia and lymphoma - Demyelination - Congestive Heart Failure - Infusion reactions - Autoimmune responses |
