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357 Cards in this Set
- Front
- Back
|
What BBW for NRTI?
|
lactic acidosis and severe hepatomegaly with steatosis
|
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|
Didanosine BBW
|
lactic acidosis, severe hepatomegaly with steatosis, pancreatitis
|
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stavudine BBW
|
lactic acidosis, severe hepatomegaly with steatosis, pancreatitis
|
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saquinavir BBW
|
tablets and hard gel caps not interchangeable
|
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ritonavir BBW
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can't coadminister with antiarrhythmic, ergot, or sedative hypnotic
|
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maraviroc BBW
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hepatotoxicity
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tipranavir BBW
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hepatotoxicity, intracranial hemorrhage
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delavirdine BBW
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need other drugs, resistance if monotherapy
|
|
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What drugs can be used for hepB/HIV coinfection?
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lamivudine, tenofavir, emtricitabine
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How many pts fail ART tx in 1st year?
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25%
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How much do condoms decrease HIV transmission?
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20x
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What HIV drugs are wt based dosing?
|
didanosine, stavudine
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What is most common HIV in US?
|
group M subtype B
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Which NRTI is metabolized by alcohol dehydrogenase?
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abacavir
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Which NRTI is metabolized by glucuronidation?
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zidovudine
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How are other NRTI metabolized?
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renal
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What age has opt out screening for HIV?
|
13-64
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|
What is a clinical response in HIV?
|
greater than 0.5 log 10 decrease in HIV RNA
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When do rapid progressors get AIDS?
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5 years or less
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When do nonprogressors get AIDS?
|
greater than 10 years
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When do you tx for HIV regardles of CD4 count?
|
preg, HIV nephropathy, Hep B
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What CD4 do you tx?
|
less than 350
|
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|
What AE for NRTI?
|
peripheral neuropathy, pancreatitis, lipoatrophy, hepatotoxicity, lactic acidosis, steatosis
|
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Are NNRTI or NRTI noncompetitive?
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NNRTI
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Which HIV is NRTI effective for?
|
HIV 1 and HIV 2
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Which HIV is NNRTI effective for?
|
HIV 1
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Which drug class has a low barrier to resistance?
|
NNRTI
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Which drug class has a high barrier to resistance?
|
PI
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What PI AE?
|
metabolic (Tg, CAD, DM), GI distress
|
|
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What does enfuviritide bind to?
|
GP41
|
|
|
Does NRTI bind to active site?
|
yes
|
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|
What is the order of HIV drugs in HIV?
|
maraviroc, enfuvirtide, RTI, integrase inhibitor, PI
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Which drug is renally dosed if CrCl is less than 60?
|
didanosine, others are less than 50
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Which drug is buffered?
|
didanosine, calcium
|
|
|
What BBW for abacavir?
|
lactic acidosis, steatosis, hypersensitivity (HLA-B 5701 allele)
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What route is enfuvirtide?
|
SQ
|
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What is the only nucleotide RTI?
|
tenofovir
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What drug has neutropenia and anemia as AE?
|
stavudine
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Which NNRTI are inhibitors of 3A4?
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delavirdine
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Which NNRTI are inducers of 3A4?
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efavirenz, nevirapine, etravirine
|
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What AE for NNRTI?
|
rash, increase liver enzymes
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|
What BBW for nevirapine?
|
rash/SJS, hepatotoxicity (dont give to women with CD4 greater than 250, men greater than 400)
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What PC is efavirenz?
|
D, teratogen
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Which drug can have a false positive marijuana or BDZ test?
|
efavirenz
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Should efavirenz be taken with food?
|
don't take with fatty foods, increase psychosis
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What is drug indicated for NNRTI resistance?
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etravirine
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What DI for PI?
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3A4, statins, rifampin
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What statin is preferred in PI tx?
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atorvastatin
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Which PI has special considerations for PPI?
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atazanavir, 12hrs after PPI, 20mg equivalent to omeprazole
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What drug causes peripheral neuropathy?
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didanosine
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Which HIV drug is moisture sensitive?
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indinavir
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Which drug causes hyperpigmentation?
|
emtricitabine
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Which drugs cause hyperbilirubinemia?
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indinavir, atazanavir
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Which PI is effective w/o ritonavir?
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atazanavir
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Which PI have to be taken with ritonavir?
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lopinavir, darunavir, tipranavir
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Which PI has the most effect on lipids?
|
ritonavir
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Which PI has least effect on lipids?
|
atazanavir
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Which drug are capsules refrigerated and solution is room temp?
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ritonavir
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|
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Trizivir
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abacavir, lamivudine, zidovudine
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What metabolizes ritonavir?
|
CYP3A4, 2D6
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How long do you prophylactic if exposed to HIV?
|
28 days
|
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When should prophylaxis be started?
|
within 72hrs
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What is prophylaxis for high risk (large blood)?
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2NRTI and PI boost
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What is prophylaxis for low risk (small blood)?
|
2 NRTI
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What is prophylaxis for urine?
|
none
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When does resistance testing for failing regimen need to be done?
|
within 4 weeks
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What type of resistance testing is preferred?
|
genotype, faster, cheaper
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What does maraviroc bind to?
|
GP120
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What does enfuvirtide bind to?
|
GP41
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Which HIV drugs are daily dosing?
|
ones in atripla (efavirenz, emtricitabine, tenofovir), abacavir, didanosine
|
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Epzicom
|
lamivudine/abacavir
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What PC is efavirenz?
|
PC D
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Which drug causes fanconi syndrome?
|
tenofovir
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Which meds should be taken with rifampin because of liver toxicity?
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saquinavir
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Which med should be avoided in alcohol?
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abacavir
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Which med can't be taken with sulfonamide allergy?
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darunavir, tipranavir, fosamprenavir
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Which med is taken 1hr apart from antacid?
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delavirdine
|
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Which HIV med has vitamin E?
|
tipranavir
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What is preferred for tx naive?
|
2NRTI + NNRTI or + PI/ritonavir or + integrase inhibitor
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What is goal for HIV RNA in tx experienced?
|
less than 400 after 24 weeks, less than 50 (undetectable) at 48 weeks, keep 50-200
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Kaletra
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lopinavir/ritonavir
|
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How does administration of Kaletra solution differ from tablet?
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solution must be taken with meals, tablet doesn't matter
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Which drug is taken with a light snack?
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nelfinavir
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When do you prophylactic for PCP?
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CD4 less than 200, pregnant, thrush
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When do you stop prophylaxis for PCP?
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CD4 above 200 for 3 months
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What is tx for PCP?
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bactrim
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What is alternative for PCP?
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dapsone
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What causes toxoplasmosis?
|
protozoan
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When do you prophylactic for toxoplasmosis?
|
less than 100
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When can you stop toxoplasmosis prophylaxis?
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over 200 for 3 months
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What is prophylactic tx for toxo?
|
bactrim
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What is alternative for prophylaxtic for toxo?
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dapsone
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What is alternative for prophylaxis and sulfonamide allergey for toxo?
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pyremethamine, clindamycin
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What is tx for toxo?
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sulfadiazine (need hydration), pyrimethazine, leucavorin
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What is alternative tx for toxo?
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dapsone, pyrimethamine
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When do you prophylact for MAC?
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CD4 less than 50
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When do you stop prophylaxis for MAC?
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CD4 greater than 100 for 3 months
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What is prophylaxis for CMV?
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don't prophylact
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When do you get CMV?
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CD4 less than 50
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When do you stop tx for CMV?
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greater than 100 for 6 months
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How long is tx if you actually get CMV?
|
lifetime
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When do you get cryptococcosis?
|
CD4 less than 100
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When do you prophylact for cryptococcosis?
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CD4 less than 50
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What is prophylaxic for cryptococcosis?
|
fluconazole
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What is tx for cryptococcosis?
|
Amph B, flucytosine, switch to fluconazole when stable
|
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What causes PCP?
|
pneumocystis jiroveci, fungus
|
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What is prophylaxis for M. tuberculosis?
|
Isoniazid (if sensitive) + pyridoxine x 9 months
alternative of if isoniazid resistant: rifampin x 4 months |
|
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What is prophylaxis for MAC?
|
azithromycin or clarithromycin
|
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What is alternative prophylaxis for MAC?
|
rifabutine
|
|
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What is tx for CMV?
|
ganciclovir or valcanciclovir or foscarnet
|
|
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What is most common manifestation of CMV?
|
retinitis
|
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What is most common presentation of cryptococcosis?
|
meningitis
|
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What is most common presentation of toxoplasmosis?
|
encephalitis
|
|
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What s/s of MAC?
|
fever, night sweats, anorexia, malaise, wt loss (more than 10%), anemia, lymphadenopathy, diarrhea
|
|
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What is tx for MAC?
|
1st drug: macrolide, clarithromycin (alternative azithromycin)
2nd drug: ethambutol 3rd: rifabutin, cipro, amikacin |
|
|
Psoriasis
|
Psoriasis
|
|
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Does smoking exacerbate psoriasis more in me or women?
|
women
|
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Does alcohol exacerbate psoriasis more in men or women?
|
men
|
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What is Koebner response?
|
psoriatic lesions at site of injury on normal skin
|
|
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What is Auspitz sign?
|
salmon pink skin and bleeding after removal of scales
|
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What is a keratolytic?
|
salicylic acid
|
|
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What AE for salicylic acid?
|
salicylism: n/v, tinnitus, hyperventilation (metabolic acidosis)
|
|
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What drugs exacerbate psoriasis?
|
NSAIDs, some antimalarials (Chloroquine), BB, Li
|
|
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What drugs for malaria prophylaxis with psoriasis?
|
proguanil, atovaquone/proguanil, doxycycline, mefloquine
not chloroquine |
|
|
Malarone
|
atovaquone/proguanil
|
|
|
Lariam
|
mefloquine
|
|
|
Daraprim
|
pyrimethamine
|
|
|
Qualaquine
|
quinine
|
|
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Fansidar
|
sulfadoxine/pyrimethamine
|
|
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What is guttate psoriasis?
|
small drop like plaques, caused by group A strep
|
|
|
What is tx for travelers diarrhea?
|
bactrim or pepto
|
|
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What is prophylactic for travelers diarrhea?
|
pepto
|
|
|
Stelara
|
ustekinumab, tx mod/sev plaque psoriasis
|
|
|
What route is stelare?
|
SQ
|
|
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What PC is Stelara?
|
B
|
|
|
What MOA of Stelare?
|
binds and interferes IL-12, IL-23, TNF alpha
|
|
|
What is required for biologics to be FDA approved?
|
75% decrease in PASI
|
|
|
What are the class 1 CS?
|
most potent, halo, betamethasone (optimized vehicle), clob (propionate)
|
|
|
What are class 7 CS?
|
hydrocortisone 1%, dexamethasone, methylprednisolone
|
|
|
What is potency measuring in CS classes?
|
vasoconstriction
|
|
|
Why are ointments better?
|
hydrating, oily occlusive phase
|
|
|
Why not use ointments in groin?
|
folliculitis
|
|
|
What SE for Vit D analogue?
|
hypercalcemia
|
|
|
What vit D analog is 100-200x less potent in its effects on calcium utilization than natural hormone?
|
calcipotriene
|
|
|
What is the topical retinoid?
|
tazarotene (Tazorac)
|
|
|
What is warning for tarotene topical?
|
don't apply to greater than 20% of body, systemic
|
|
|
What AE for coal tar?
|
epidermal hyperplasia, odorous
|
|
|
How does anthralin work?
|
DNA intercalation
|
|
|
How do you know anthralin is working?
|
skin staining
|
|
|
Are topical calcineurin inhibitors approved for psoriasis?
|
no, tacrolimus, pimacrolimus
|
|
|
What benefit of calcineurin inhibitors over CS?
|
don't cause skin atrophy
|
|
|
What are the TNF alpha inhibitors?
|
infliximab, adalimumab, etanercept
|
|
|
What is a T cell activation inhibitor?
|
Alefacept, CD2
|
|
|
When should alefacept be stopped?
|
if CD4 is below 250
|
|
|
Why was efalizumab pullef from the market?
|
PML (progressive multifocal leukoencephalopathy)
|
|
|
What do you give with acitretin for hyperlipidemia?
|
gemfibrizil
|
|
|
What AE for acitretin?
|
hypervitaminosis A
|
|
|
How long off of acitretin before pregnancy?
|
off for 3 years before pregnancy
|
|
|
How long should women not consume alcohol after acitretin?
|
2 months
|
|
|
What is goeckerman therapy?
|
UVB + Tar
|
|
|
What is Ingram therapy?
|
UVB + anthralin
|
|
|
What is PUVA?
|
psoralen + UVA
|
|
|
What is spectrum of UVB?
|
290-330, 310-315 is best, lights 310-313
|
|
|
How long before light does methoxypsoralen need to be applied?
|
2hrs, light breaks it down
|
|
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Does PUVA systemic or topical need higher dose?
|
systemic (more melanoma)
|
|
|
What is the most effective approach to psoriasis?
|
goekerman therapy
|
|
|
What route is infliximab?
|
IV
|
|
|
What route is alefacept?
|
IM
|
|
|
What route are other biologics?
|
SQ
|
|
|
VVC
|
VVC
|
|
|
What are s/s of bacterial vaginosis?
|
Ph greater than 4.5, fishy, gray/white
|
|
|
What are s/s trich infection?
|
pH elevation, bad smell, yellow/green frothy
|
|
|
What is normal discharge?
|
white/clear
|
|
|
Does IUD increase risk of VVC?
|
yes
|
|
|
What is tx for bacterial vaginosis?
|
metronidazole
|
|
|
What is alternative tx for bacterial vaginosis?
|
clindamycin
|
|
|
What is tx for trich?
|
metronidazole, tinidazole
|
|
|
What is tx for VVC?
|
azole
|
|
|
What is complicated VVC?
|
more than 4 in 12 months, severe, non albicans, preg,
|
|
|
What is tx for complicated?
|
boric acid, flucytosine
|
|
|
What is 2nd most common candida?
|
glabratta
|
|
|
What is tx for glabratta?
|
flucytosine
|
|
|
Why does estrogen (OC) increase risk of VVC?
|
increase binding affinity of fungus
|
|
|
What is tx if trich and allergic to metronidazole or tinidazole?
|
desensitize
alternative: douche |
|
|
Which infection do you treat the partner?
|
trich
|
|
|
When are metronidazole and tinidazole CI?
|
1st trimester pregnancy
metronidazole PC B, tinidazole PC C |
|
|
How long for VVC tx?
|
1, 3, or 7 day
|
|
|
How long for complicated VVC tx?
|
10-14 days
|
|
|
What is diagnosis for bacterial vaginosis?
|
KOH, wiff test
|
|
|
Is VVC a STD?
|
no
|
|
|
Monistat 3, 7, combo pack
|
miconazole
|
|
|
Femstat
|
butoconazole 2% OTC
|
|
|
Gynazole 1
|
butoconazole 2% sustained release
|
|
|
Lotrimin AF
|
clotrimazole
|
|
|
Terazol
|
terconazole
|
|
|
Monistat 1/ Vagistat 1
|
tioconazole
|
|
|
What are the Rx tx for VVC?
|
nystatin, clotrimazole vag tab, gluconazole, terconazole
|
|
|
Parkinson's
|
Parkinson's
|
|
|
What are symptoms of PD?
|
bradykinesia, postural disturbances, rigidity, tremor
|
|
|
What age most common for PD?
|
65-80 years
|
|
|
What street drug can cause PD?
|
MPTP, meperidine analog
|
|
|
How many receptors must you lose for PD?
|
70-80%
|
|
|
What are Lewey bodies?
|
abnormal aggregates of protein in nerve cells in PD
|
|
|
How is DA and Ach affected in PD?
|
DA down, Ach up
|
|
|
What is first symptom of PD?
|
tremor, unilateral
|
|
|
What is stage 1 PD?
|
unilateral
|
|
|
What is stage 2 PD?
|
bilateral
|
|
|
What is stage 3 PD?
|
postural instability
|
|
|
What is stage 4 PD?
|
need assistance
|
|
|
What is stage 5 PD?
|
need assistance/bed bound, doesn't respond to drugs
|
|
|
How does rigidity present?
|
cogwheel
|
|
|
How does tremor present?
|
pill rolling
|
|
|
When do you start PD tx?
|
bradyinesia/rigidity
|
|
|
Stalevo
|
carbidopa/levodopa/entacapone
|
|
|
Max dose/day Stalevo?
|
6x
|
|
|
Max dose/day of carbidopa/levodopa or entacopone?
|
8x/day
|
|
|
Max dose/day of tolcapone?
|
3x
|
|
|
What converts Ldopa to DA?
|
dopadecarboxylase
|
|
|
What converts Ldopa to 3 O methyl dopa?
|
COMT
|
|
|
What is ropinorole metabolized by?
|
1A2
|
|
|
What AE from DA agonist?
|
orthostatic hypotension, change in mood behavior, hallucinations, somnolence, nausea
|
|
|
What is tx for increased somnolence?
|
provigil (modafanil)
|
|
|
What BBW tolcapone?
|
liver damage
|
|
|
Is pramipexole or ropinorole more poten?
|
pramipexole, 3x
|
|
|
What major SE of amantadine?
|
livedo reticularis
|
|
|
Selegiline
|
eldepryl, MAO-B inhibitor
|
|
|
Selegiline ODT
|
zelapar, MAO-B inhibitor
|
|
|
What kind of metabolites does selegiline have?
|
amphetamine
|
|
|
Why was rotigatine patch voluntarily withdrawn?
|
pathc, crystals affect absorption
|
|
|
What happens if ldopa or DA agonist is withdrawn to quickly?
|
neuroleptic malignant syndrome
|
|
|
What is half life of ldopa?
|
1.5hrs
|
|
|
What metabolizes selegiline?
|
CYP2B6, 3A4
|
|
|
How much carbidopa is needed to saturate dopadecarboxylase?
|
75-100mg
|
|
|
Parcopa
|
carbidopa/levodopa ODT
|
|
|
What ratio of carbidopa/ldopa if less than 750mg?
|
4:1
|
|
|
What ration of carbidopa if more than 750mg?
|
10:1
|
|
|
What DI CI for selegiline?
|
dextromethorphan and meperidine
|
|
|
What dose of selegiline become not selective for MAO-B?
|
high dose, 20mg, watch what you eat
|
|
|
What CrCl for pramipexole?
|
IR: greater than 60 ok, ER: greater than 50 ok
|
|
|
What does ropinorole (Requip) have affinity for?
|
D3
|
|
|
How long is honeymoon period?
|
5 years
|
|
|
What AE for apomorphine?
|
n/v
|
|
|
What is tx for n/v from apomorphine?
|
trimethobenzamide 3 days prior for 2 months, don't give zofran because hypotension
|
|
|
What is test dose for apomorphine?
|
0.1mL
|
|
|
What route is apomorphine?
|
SQ
|
|
|
What DI for anticholinergics and ldopa?
|
stops stomach and stops clearance
|
|
|
What DI for ferrous sulfate and ldopa?
|
chelation, decrease absorption by 50%
|
|
|
Why are anticholinergic not given to older people?
|
AE, mental
|
|
|
What metabolizes tolcapone?
|
2D6, 3A4
|
|
|
What cranial nerves are affected in PD?
|
5 (jaw), 7 (facial fold), 10 (swallowing), 11 (en bloc), 12 (tongue)
|
|
|
What can amantadine cause after 1-3 months?
|
tachyphylaxis
|
|
|
What PD drugs are renal dosed?
|
pramipaxole and amantadine
|
|
|
What climate worsens livedo reticularis?
|
cold
|
|
|
Apokine
|
apomorphine
|
|
|
Does CR or IR Sinemet have higher dyskinesia?
|
CR
|
|
|
What MOA of CoQ10?
|
mitochondrial synthesis
|
|
|
What Vit E in PD?
|
alpha tocopherol
|
|
|
Bipolar
|
Bipolar
|
|
|
When is lamotrigine used?
|
maintenance only
|
|
|
What bipolar med can be used by 12 year old?
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lithium
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Does Li dose change in pregnancy?
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increase
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What is Li liquid?
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Li citrate
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How much IR Li is absorbed?
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90-100%
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How much Liquid Li is absorbed?
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100%
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How much ER Li is absorbed?
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60-90%
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What Li toxicity above 1.5?
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apathy, lethargy, nausea
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What Li toxicity 1.5-2.5?
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coarse tremor, slurred speech
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What Li toxicity above 2.5?
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seizure, renal failure, coma
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What do you do if Li level is above 4?
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intermittent hemodialysis
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When does ebstein anomally occur?
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Li, 1st trimester
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Which bipolar drug is worst in pregnancy?
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valproate, neural tube defects 1:20
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What birth defect for CBZ?
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0.1% neural tube defects
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What birth defect for Li?
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Ebstein Anomaly 1:1000
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What PC Li, valproate, CBZ?
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D
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Can you breast feed with valproate?
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yes
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Can you breast feed with Li?
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no
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What med for pregnancy?
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typical AP (chlorpromazine), CCB
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M-Tab
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risperdone ODT
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Zydis
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olanzapine ODT
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Discmelt
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aripiprazole ODT
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What BBW for lamotrigine?
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skin reactions, SJS
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What can exacerbate psoriasis?
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Li
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What program for pregnant if continue lamotrigine?
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NAAED
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What sex more likely to get bipolar I or II?
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women
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What sex more likely to get subthreshold bipolar?
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men
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What drug CI with CBZ?
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nefazodone
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Symbyax
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olanzapine/fluoxetine
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What BBW CBZ?
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aplastic anemia, agranulocytosis
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How does CBZ induce its own metabolism?
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3A4
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Does hyper/hypo thyroid cause mania?
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hyperthyroid
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Triliptel
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oxcarbazepine
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What Li concentration for acute bipolar?
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1-1.2
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What Li concentration for maintenance?
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0.6-0.8
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What Li concentration for elderly?
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0.4-0.6
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What BBW for valproate?
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hepatotoxicity, teratogenicity, pancreatitis
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What AE for valproate?
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hyperammonemic encephalopathy
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What must you do before starting antidepressant in bipolar?
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stabilized on mood stabilizer
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Which IM AP is not given with BDZ?
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olanzapine, respiratory depression
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CBZ/valproate combo results?
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valproate displaces CBZ, CBZ levels increase
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What is the worst AAP with Li?
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aripiprazole, t1/2 to long to calm down quick
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What is better AAP with Li?
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risperidone
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When is Li stopped/restarted with ECT?
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d/c 2 days before, start back 2-3 days after
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What drugs shouldn't be given with Li?
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NSAIDs, ACEI, thiazide (reabsorb more Li), caffeine/theophylline
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How does Li cause diarrhea?
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osmotic
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When is CR Li taken?
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night
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Does Li affect liver?
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no
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What drug can cause prolonged bleeding?
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valproate
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What are goal valproate levels?
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50-125mcg/mL 12hrs post dose
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What OTC for bipolar?
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omega 3 FA
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ANAPHYLAXIS What wt gets epi pen?
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above 30kg
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What wt gets epi pen Jr?
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below 30kg
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What concentration for epi pen?
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1:1000
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What concentration for epi pen Jr?
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1:2000
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What is dose of epi pen?
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0.3mg/0.3ml
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What is dose of epi pen Jr?
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0.15mg/0.3ml
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How long do you wait when giving epi pen?
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10 seconds
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Where is epi pen given?
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anterolateral aspect of the thigh
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What is type I rxn?
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IgE
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Whay is type II rxn?
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cytotoxic, IgG, IgM
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What is type III rxn?
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serum sickness, IgE, immune complex
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What is type IV rxn?
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cell mediated, delayed HSN, CD4/CD8
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What is example of Type IV?
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TB skin test, poison ivy
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Does 1st or 2nd gen cephs cause more anaphylaxis?
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1st
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What kind of rxn is red man syndrome?
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anaphylactoid, doesn't involve IgE, direct release of Histamine
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What is an example of type III rxn?
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lupus
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What causes the most anaphylaxis/phylactoid rxn?
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ASA/NSAIDs, pens, insulin
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How long do you monitor pt after anaphylaxis?
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12hrs for delayed rxn
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What route is least likely to make you sensitive?
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IV
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What route is most likely to make you sensitive?
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topical
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Do you need to be sensitized for anaphylactoid?
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no
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What type of rxn is pen rxn?
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can be all 4
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Can you give aztreonam if have pen allergy?
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yes
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Can you give carbopenem if have pen allergy?
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no
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What do you give have anaphylaxis and on BB?
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glucagon
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What vasopressor is recommended?
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NE
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What is used to reduce late phase rxn?
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hydrocortisone
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What is used for bronchospasm?
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albuterol and aminophylline
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How often vital for anaphylaxis?
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every 2-5 minutes
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WhHow much oxygen for anaphylaxis?
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8-10L/minute
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Transplant
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Transplant
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What transplant has the best survival?
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kidney
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What transplant has the lowest survival?
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heart
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Can you get a transplant if have HIV?
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yes
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What is absolute CI for heart transplant?
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infection, other diseases, malignancies, severe irreversible pulmonary HTN
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What is absolute CI for liver transplant?
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HCV in 6 months after transplant, HCV at anytime, alcohol or substance abuse
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What is CI for kidney transplant?
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unstable cardiac disease, malignancies, risk from surgery, chronic immunosuppression
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What is reason for most liver transplants?
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noncholistatic cirrhosis (hep C)
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What are calcineurin inhibitors metabolized by?
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3A4
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What premedication of polyclonal antibodies?
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diphenhydramine, hydrocortisone, acetaminophen
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Which transplants ned HLA matching?
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kidney
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What AE for cyclosporine?
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HTN (BBW), hyperlipidemia
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What AE fror tacrolimus?
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hyperglycemia, alopecia
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How do you know if you have acute rejection with heart transplant?
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asymptomatic, routine biopsy
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Is chronic rejection reversible?
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no
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What PC for basaliximab?
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B
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What is MOA of basiliximab?
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IL-2 antagonist
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What is empiric tx if rejection is suspected?
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high dose corticosteroids (methyprednisolone IV)
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