Resting Membrane Potential

Front 1

Resting membrane

Back 1

-voltage membrane based on concentrations, in excitable cells (neuron) and non excitable (skeletal/)
is keeping inside of a neuron (-70) and skeletal (-90) negative at resting why?
1) attain necessary charges for depolarization
2)K are permeable, conductible they leak out of cell, making ICF more negative
3) Atpase pump Na and K against their concentration gradient
4) this is necessary to trigger action potential

Front 2

Permeability

Back 2

K very permeable (goes out) more inside
Cl- more outside (not permeable)
Ca- lots outside!!!!! (not permeable to go inside)
Na- more inside (less permeable)
not allowing any anions go outside to main resting potential's negative polarity inside the cell

Front 3

Atpase

Back 3

pumps are not directly involved in triggering action potential but very necessary to begin action potential

Front 4

membrane potential

Back 4

1) permeability of cell membrane
2) polarity of electric charge
3) ion concentrations inside and outside of cell

Front 5

excitable cells where resting membranes established

Back 5

neuron, muscle, glands

Front 6

small conductance of K

Back 6

K+ leaks
leakage) of K+ down its concentration gradient (i.e. towards the outside of the cell) this creates a negative voltage (resting potential) inside the cell. At rest the membrane potential is about -70mV
K inside
Na outside

AtPase keeps K from going out or NA from going in ?
It keeps taking NA out and putting K back into cell??