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29 Cards in this Set
- Front
- Back
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Corticosteroids Physiology
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are effective in treating an already established inflammatory response
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Corticosteroid mechanism of action
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Block or diminish late-phase asthma response by blocking arachidonic acid cascade of metabolites.
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Inflammatory response Early phase
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Local vasodilation, increased vascular permeability, redness, bronchial constriction, SOB, cough dyspnea, hypoxemia, tight chest
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Inflammatory response Late phase
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Develops 6-8 hrs later. More difficult to resolve than early phase. Hypersecretion of mucus.
Increased vascular permeability. |
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List Corticosteroids by the generic name
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Beclomethasone dipropionate , Beclomethasone, Diproprionate, Budesonide, Flunisolide, Fluticasone, Mometasone furoate, triamcinolone acetonide
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Beclomethasone dipropionate trade name and low, medium, high doses are...
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Beclovent 168-504 mcg
504-840 mcg >840 mcg |
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Beclomethasone low, medium, high doses are...
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• 80-240 mcg twice daily
• 240-280 mcg twice daily • >480 mcg |
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Diproprionate low, medium, high doses are...
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• 200-600 mcg
• 600-1,200 mcg • >1,200 mcg |
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Budesonide DPI trade name and low, medium, high doses are...
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Pulmicort
• 200-600 mcg • 600-1,200 mcg • >1,200 mcg |
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Budesonide SVN trade name and low, medium, high doses are...
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Pulmicort Respules
• 0.25 mg/ 2.0 cc NSS • 0.5 mg/ 2.0 cc NSS • 1.0 mg/ 2.0 cc NSS *Only steroid that can be nebulized* |
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Flunisolide trade name and low, medium, high doses are...
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Aerobid
• 500-1,000 mcg • 1,000-2,000 mcg • >2,000 mcg |
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Fluticasone MDI trade name and low, medium, high doses are...
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Flovent MDI
• 88-264 mcg * 264-660 mcg • >660 mcg |
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Fluticasone DPI trade name and low, medium, high doses are...
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Flovent DPI
• 100-300 mcg * 300-600 mcg • >600 mcg |
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Mometasone furoate trade name and low, medium, high doses are...
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Asmanex
• 220 mcg • 220 mcg b.i.d. • 440 mcg b.i.d. |
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Triamcinolone acetonide trade name and low, medium, high doses are...
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Azmacort
• 400-1,000 mcg • 1,000-2,000 mcg • >2,000 mcg |
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Advair has what two Combined Medications
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Salmeterol and fluticasone
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Advair DPI dosages are...
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DPI inhaler
• 100mcg / 50 mcg • 240mcg / 50 mcg • 500mcg / 50mcg |
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Advair HFA dosages are...
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HFA inhaler
• 45 mcg / 21 mcg • 115 mcg / 21 mcg • 230 mcg / 21 mcg |
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Symbicort has what two Combined Medications
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Formolerol and buesonide
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Symbicort HFA dosages are...
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HFA inhaler
• 80 mcg / 4.5 mcg • 160 mcg / 4.5 mcg |
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Anti-asthmatics Physiology
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attempt to stabilize the mast cell membrane and therefore prevent its rupture. Works to inhibit calcium influx into the mast cell.
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Anti-asthmatics generic drug names are...
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• Cromolyn Sodium
• Nedocromil Sodium |
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Cromolyn Sodium trade name and doses are...
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Intal
• MDI 800mcg 2 inhalations q.i.d. • SVN 20 mg/ampule q.i.d. |
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Nedocromil Sodium trade name and doses are...
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Tilade
MDI 1.75 mg 2 inhalations q.i.d. |
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Leukotriene Modifiers Physiology
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Inhibits the leukotriene mediator cascade that leads to airway inflammation. Used for long rm control of asthma.
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Leukotriene Modifiers generic drug names are...
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• Zafirlukast
• Montelukast • Zileutron |
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Zafirlukast trade name and doses are...
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Accolate
10 mg, 20 mg one tablet b.i.d. |
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Montelukast trade name and doses are...
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Singular
10 mg one tablet each evening |
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Zileutron trade name and doses are...
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Zyflo
600 mg one tablet q.i.d. |
