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28 Cards in this Set

  • Front
  • Back

Anti-inflammatory


Inhaled Corticosteroid


Beclomethasone

Bind to specific intracellular cytoplasmic glucocorticoid/mineral corticoid receptors throughout the body


The receptor-hormone complex acts in the nucleus to regulate gene transcription


Decreases the inflammatory cascade by reducing the hyper-responsiveness of airway smooth muscle after several months of regular use

Anti-inflammatory


Inhaled corticosteroid


Budesonide

Bind to specific intracellular cytoplasmic glucocorticoid/mineral corticoid receptors throughout the body


The receptor-hormone complex acts in the nucleus to regulate gene transcription


Decreases the inflammatory cascade by reducing the hyper-responsiveness of airway smooth muscle after several months of regular use

Anti-inflammatory


Inhaled corticosteroid


Ciclesonide

Bind to specific intracellular cytoplasmic glucocorticoid/mineral corticoid receptors throughout the body


The receptor-hormone complex acts in the nucleus to regulate gene transcription


Decreases the inflammatory cascade by reducing the hyper-responsiveness of airway smooth muscle after several months of regular use

Anti-inflammatory


Inhaled corticosteroid


Flunisolide

Bind to specific intracellular cytoplasmic glucocorticoid/mineral corticoid receptors throughout the body


The receptor-hormone complex acts in the nucleus to regulate gene transcription


Decreases the inflammatory cascade by reducing the hyper-responsiveness of airway smooth muscle after several months of regular use

Anti-inflammatory


Inhaled corticosteroid


Fluticasone

Bind to specific intracellular cytoplasmic glucocorticoid/mineral corticoid receptors throughout the body


The receptor-hormone complex acts in the nucleus to regulate gene transcription


Decreases the inflammatory cascade by reducing the hyper-responsiveness of airway smooth muscle after several months of regular use



Anti-inflammatory


Inhaled corticosteroid


Mometasone

Bind to specific intracellular cytoplasmic glucocorticoid/mineral corticoid receptors throughout the body


The receptor-hormone complex acts in the nucleus to regulate gene transcription


Decreases the inflammatory cascade by reducing the hyper-responsiveness of airway smooth muscle after several months of regular use

Anti-inflammatory


Systemic Corticosteroid

Bind to specific intracellular cytoplasmic glucocorticoid/mineral corticoid receptors throughout the body


The receptor-hormone complex acts in the nucleus to regulate gene transcription


Decreases the inflammatory cascade by reducing the hyper-responsiveness of airway smooth muscle after several months of regular use

Anti-inflammatory


Mast cell stabilizer


Cromolyn

Blocks the release of inflammatory mediators, preventing the allergic response from happening in the first place

Anti-inflammatory


Anti-leukotriene


Montelukast

Blocks the effects of leukotrienes (leukotrienes are products of the arachidonic acid metabolism, functioning in the inflammatory cascade)

Anti-inflammatory


Anti-leukotriene


Zafirlukast

Blocks the effects of leukotrienes (leukotrienes are products of the arachidonic acid metabolism, functioning in the inflammatory cascade)

Anti-inflammatory


Anti-leukotriene


Zlieuton

Inhibits 5-lipoxygenase, preventing the formation of leukotrienes in the first place

Bronchodilators


Short acting B2 agonist


Albuterol

Agonist at the adrenergic receptor (Activation of beta-adrenergic receptors leads to relaxation of smooth muscle in the lung, and dilation and opening of the airway)


NO ANTI-INFLAMMATORY ACTION

Bronchodilators


Short acting B2 agonist


Levalbuterol

Agonist at the adrenergic receptor (Activation of beta-adrenergic receptors leads to relaxation of smooth muscle in the lung, and dilation and opening of the airway)


NO ANTI-INFLAMMATORY ACTION

Bronchodilators


Short acting B2 agonist


Pirbuterol

Agonist at the adrenergic receptor (Activation of beta-adrenergic receptors leads to relaxation of smooth muscle in the lung, and dilation and opening of the airway)


NO ANTI-INFLAMMATORY ACTION

Bronchodilators


Long acting B2 agonist


Formoterol

Agonist at the adrenergic receptor (Activation of beta-adrenergic receptors leads to relaxation of smooth muscle in the lung, and dilation and opening of the airway)


NO ANTI-INFLAMMATORY ACTION

Bronchodilators


Long acting B2 agonist


Indacaterol

Agonist at the adrenergic receptor (Activation of beta-adrenergic receptors leads to relaxation of smooth muscle in the lung, and dilation and opening of the airway)


NO ANTI-INFLAMMATORY ACTION

Bronchodilators


Long acting B2 agonist


Salmetrol

Agonist at the adrenergic receptor (Activation of beta-adrenergic receptors leads to relaxation of smooth muscle in the lung, and dilation and opening of the airway)


NO ANTI-INFLAMMATORY ACTION

Other bronchodilator (Cholinergic antagonist)


Ipratropium

Block contraction of airway smooth muscle mediated by the vagus nerve by blocking acetylcholine receptors

Other bronchodilator (Cholinergic antagonist)


Tiotropium

Block contraction of airway smooth muscle mediated by the vagus nerve by blocking acetylcholine receptors

Other bronchodilator


Theophylline

Bronchodilator that increases cAMP and antagonizes the adenosine receptors

Immunoglobulin Antagonist


Omalizumab

Recombinant DNA monoclonal antibody that selectively binds to IgE, decreasing the release of inflammatory mediators from mast cells and basophils

Antitussive/Expectorant


Codeine

Decreases sensitivity of cough centers in the CNS to peripheral stimuli, decreases mucosal secretion

Antitussive/Expectorant


Diphenhydramine

Antihistamine that blocks the H1 receptor

Antitussive/Expectorant


Fexofenadine

Antihistamine that blocks the H1 receptor

Antitussive/Expectorant


Loratadine

Antihistamine that blocks the H1 receptor

Antitussive/Expectorant


Dextromethorphan

No analgesic effect at antitussive doses


Equally as effective as codeine (decreases sensitivity of cough centers in CNS to peripheral stimuli and decreases mucosal secretion)

Antitussive/Expectorant


Local anesthetic


Benzonatate

Anesthetizes respiratory passage and pleural stretch receptors to reduce cough reflex

Antitussive/Expectorant


Gauifenesin

Facilitates coughing up of mucous by reducing adhesiveness and surface tension of respiratory tract secretions


Reduces frequency of cough