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10 Cards in this Set

  • Front
  • Back
Basic structure and anatomy
Nasal cavity
Pharynx
larynx
trachea
bronchii
alveoli
lungs
Importance of the alveoli
Alveoli and Alveolar sac
Surrounded by blood vessels where gas exchange occurs btwn air and blood
Pulmonary surfactant
coats inner surface of alveoli
Reduces surface tension and reduces the effort needed to expand the lung
Without it – lungs would collapse
3 operations for gas exchange
Ventilation
moving air in and out of lungs
Perfusion
movement of blood through pulmonary vessels
Diffusion
O2 enters blood, and CO2 leaves
Ventilation – inspiration/expiration and pressure change associated with each
Ventilation
moving air in and out of lungs

Inspiration
pressure outside is > pressure in lungs
muscles are contracted to draw air deep into lungs

Expiration
at rest; passive process
pressure inside is greater
elastic recoil- thoracic walls and lungs spring back
Requirements for ventilation
Rate of ventilation (must be high enough to maintain homeostasis)

Requirements:
Open airways
Defense mechanisms
insure clean, warm moist air enters lungs
cough, gag and swallowing reflexes
Proper pressure changes
in thoracic cavity and lungs
Compliance
thoracic cavity and lungs must easily expand
Control systems
nervous system
Lung volume- vital capacity, residual volume,
Tidal Volume
volume inspired=volume expired (normal breathing at rest)
Inspiratory reserve volume (IRV) - extra amount one can inspire

Expiratory reserve volumeERV -extra amount one can expire

Vital capacity - TV + IRV + ERV =VC
Residual volume
air remaining in lungs after expiration
VC + RV = TLC (total lung capacity)
Recognize age changes in ventilation, alveoli and structure
Ventilation:
decrease rate air can flow in system
increase work of breathing (incr CO2 in blood)
decrease in IRV and ERV, increase in RV = decrease in vital capacity
decrease in minute volume (by 50%)
decrease max rate of gas exchange

Alveoli
Loss of alveolar walls increase the size and reduce functional surface for gas exchange
Cross-linkages develop between collagen fibers in the walls of alveoli
Ratio of collagen to elastic fibers ↑

Impairs the ability of the alveoli to expand during inspiration = ↓ compliance = ↓ ventilation

Lower percentage of oxygen available in alveoli is able to pass to the lung capillaries
↓ oxygen level in arterial blood
Relationship between lung function and exercise
Lung Function and Exercise

Because there are no muscles in the walls of the lungs
Diaphragm and respiratory muscles of the chest can be strengthened by exercise

Ultimately, it is unclear whether exercise has any significant effect on lung elasticity
Lung elasticity = important factor in respiratory function
Tidal volume and vital capacity are not improved significantly by exercise.
Pulmonary edema, pulmonary fibrosis, lung cancer, COPD (chronic bronchitis, asthma and emphysema), pneumonia, tuberculosis
Pulmonary Edema:
Swelling and/or fluid accumulation in the lungs
Impaired gas exchange
Respiratory failure

Symptoms: difficulty breathing, coughing up blood, anxiety, pale skin + excessive sweating, pink frothy sputum

pulmonary fibrosis:
Caused by prolonged inflammation
Lungs become replaced by fibrotic tissue leading to an irreversible loss of the tissues ability to transfer O2 into the bloodstream
Excessive build up of scar tissue isn’t normal

In pulmonary fibrosis damage to the alveoli causes the thin tissue that separates alveoli to scar.
Symptoms: SOB, chronic dry hacking cough, chest discomfort, fatigue and weakness
Hypoxemia – low blood oxygen levels
Autoimmune or viral in nature.
Effect of smoking on the respiratory system
Carcinogens (cancer causing agents) damage the cells that line the lungs.

After repeated exposure, the body is unable to repair damage.

Abnormal changes in the cell can lead to cancer.

Blood and lymph vessels in the lung allow cancer to spread easily to other parts of the body.