Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
67 Cards in this Set
- Front
- Back
|
Amiloride is... |
A sodium channel blocker that is a functional antagonist of aldosterone (also a K-sparing diuretic) |
|
|
Conivaptan is... |
A specific V2 receptor antagonist |
|
|
Canrenone is... |
An aldosterone receptor blocker |
|
|
Elperenone is... |
An aldosterone receptor blocker (also a K-sparing diuretic) |
|
|
Spironolactone is... |
An aldosterone receptor blocker (also a K-sparing diuretic) |
|
|
Triamterene is... |
A sodium channel blocker that is a functional antagonist of aldosterone (also a K-sparing diuretic) |
|
|
Mannitol is... |
An osmotic diuretic |
|
|
Glycerol is... |
An osmotic diuretic |
|
|
Torsemide is... |
A loop diuretic |
|
|
Bumetanide is... |
A loop diuretic |
|
|
Ethacrynic acid is... |
A loop diuretic |
|
|
Hydrochlorothiazide is... |
A thiazide diuretic |
|
|
Indapamide is... |
A thiazide like diuretic |
|
|
Xipamide is... |
A thiazide like diuretic |
|
|
Chlortalidone is... |
A thiazide like diuretic |
|
|
Metolazone is... |
A thiazide like diuretic |
|
|
Acetazolamide is... |
A carbonic anhydrase inhibitor |
|
|
Dorzolamide is... |
A carbonic anhydrase inhibitor |
|
|
Methazolamide is... |
A carbonic anhydrase inhibitor (note the azolamide suffix) |
|
|
Lixivaptan is... |
A specific V2 receptor antagonist |
|
|
State 5 different classes of diuretic drugs (by mechanism of action) with an example of each |
1. CA inhibitors e.g. acetylzolamide
2. Loop diuretics e.g. furosemide 3. Thiazide diuretics e.g. bendroflumethiazide 4. Osmotic diuretics e.g. mannitol 5. Functional aldosterone antagonists (sodium channel blockers) e.g. amiloride 6. Direct aldosterone antagonists e.g. spironolactone |
|
|
Prazosin is a... |
Alpha-1 selective adrenoceptor antagonist |
|
|
Amrinone is a... |
Positive inotrope and PDE-III inhibitor |
|
|
Milrinone is a... |
Positive inotrope and PDE-III inhibitor |
|
|
Hydralazine is a... |
Directly acting vasodilator |
|
|
Class I anti-arrhythmic agents are... |
Na channel blockers |
|
|
Lidocane is a... |
Class IB anti-arrhythmic agent |
|
|
Flecainide is a... |
Class IC anti-arrhythmic agent |
|
|
Quinidine is a... |
Class IA anti-arrhythmic agent |
|
|
Amiodarone is a... |
Potassium channel blocker |
|
|
Tocainide is a... |
Class IB anti-arrhythmic agent |
|
|
Mexilitine is a... |
Class IB anti-arrhythmic agent |
|
|
Encainide is a... |
Class IC anti-arrhythmic agent |
|
|
Propafenone is a... |
Class IC anti-arrhythmic agent |
|
|
Procainamide is a... |
Class IA anti-arrhythmic agent |
|
|
Disopyramide is a... |
Class IA anti-arrhythmic agent |
|
|
Sotalol is a... |
K channel blocker |
|
|
Bretylium is a... |
K channel blocker |
|
|
Deslanoside is a... |
Positive inotrope and cardiac glycoside |
|
|
Xamoterol is a... |
B1 adrenoceptor partial agonist |
|
|
Minoxidil is... |
A directly acting vasodilator |
|
|
Nicorandil is a... |
Potassium channel opener and organic nitrate |
|
|
Simvastatin is a... |
HMG-CoA reductase inhibitor |
|
|
Ezetimibe is a... |
Specific cholesterol absorption inhibitor |
|
|
Colestyramine is a... |
Bile acid-binding resin |
|
|
Colestipol is a... |
Bile acid-binding resin (note the cole prefix) |
|
|
Nicotinic acid (niacin) is... |
A B-viamin that reduces lipolysis by inhibiting hormone sensitive lipase |
|
|
Acipimox is a... |
Longer acting, synthetic derivative of niacin |
|
|
Alpha-linoeic acid is a... |
Omega-3-fatty acid which reduces triglyceride levels |
|
|
Eicosapentaenoic acid (EPA) is a... |
Omega-3-fatty acid which reduces triglyceride levels |
|
|
Docosahexaenoic acid (DHA) is a... |
Omega-3-fatty acid which reduces triglyceride levels |
|
|
State 5 different classes of lipid lowering agents (by mechanism of action) with an example of each |
HMG-CoA reductase inhibitors: e.g. simvastatin Fibrates (PPAR-alpha activators): e.g. bezofibrate Bile acid-binding sequesterants: e.g. Colestyramine B-vitamins aka inhibitors of hormone sensitive lipase: e.g. niacin Omega-3-fatty acids, reduce triglyceride levels e.g. eicosopentoic acid |
|
|
State examples of Omega-3-fatty acids as drugs |
Docosahexaenoic acid (DHA), Eicosapentaenoic acid (EPA), Alpha-linoeic acid |
|
|
State a longer acting, synthetic derivative of niacin |
Acipimox |
|
|
State a B-viamin that reduces lipolysis by inhibiting hormone sensitive lipase |
Niacin |
|
|
State K channel blockers
|
Sotalol, beryllium and amiodarone |
|
|
State Bile acid-binding resin |
Colestryamine and Colestipol (cole prefix) |
|
|
Omalizumab (Xolair) is a... |
Anti-IgE (monoclonal IgG that prevents IgE binding to receptors on mast cells)
|
|
|
Mepolizumab is a... |
Anti IL-5 monoclonal antibody |
|
|
Oxymetazoline is a... |
Alpha-1 adrenceptor agonist |
|
|
Salmeterol is a... |
Long acting beta-2 agonist |
|
|
Theophylline is a.... |
Non-specific PDE inhibitor |
|
|
Ipratropium is a... |
M3 selective antagonist |
|
|
Zileuton is an....
|
Inhibitor of leukotriene synthesis |
|
|
Roflumilast is a...
|
PDE-4 inhibitor, causing building up of cAMP in immune cells, leading to there death |
|
|
Bupropion is a... |
nAChR partial agonist ant antidepressant used in stop smoking therapy |
|
|
Tiotropium is a... |
mAChR3 antaogonist (long acting) |
