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25 Cards in this Set
- Front
- Back
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diphenhydramine
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1st gen H1 blocker
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demenhydrinate
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1st gen H1 blocker
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chlorpheniramine
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1st gen H1 blocker
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uses of first 1st gen H1 blockers
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allergy, motion sickness, sleep aid
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toxicities of 1st gen H1 blockers
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sedation, anti muscarinic, anti α1
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loratidine
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2nd gen H1 blocker
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fexofenadine
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2nd gen H1 blocker
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desloratidine
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2nd gen H1 blocker
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cetirizine
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2nd gen H1 blocker
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Isoproterol
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non specific beta agonist - relaxes bronchial SM but tachycardia
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Albuterol
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beta 2 agonist, relaxes bronchial SM
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Salmterol
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long acting beta 2 agonist for prophyalxis
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salmeterol SE
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tremor, arrhythmias (black box)
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theophylline
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inhibits phoschodiesterase --> decrease cAMP hydrolysis
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what drug does theophylline block?
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adenosine
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SE of theophylline
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narrow therapeutic index - cardiotox, neurotox
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ipratropium
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block M3 receptors, preventing bronchoconstriction
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cromoyln
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prevent release of mediators from mast cells
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corticosteroids for asthma
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inactivates NF-kB (TF for TNFα) --> inhibits synthesis of cytokines
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Zileuton
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5 lipoxygenase pathway inhibitor; blocks arachdonic acid --> LTs
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Zafirulkast, montelukast
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block LT receptors
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which drug is best for aspirin induced asthma?
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Zafirlukast, montelukast
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Guaifenesin
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expectorant - removes excess sputum
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N-acetylcystein
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mucolytic - cleaves S-S bonds in mucous
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Bosentan
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antagonizes endothelin-1 receptors --> decrease pulmonary vascular R
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