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10 Cards in this Set
- Front
- Back
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ASTHMA drugs
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Albuterol MOA
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relaxes bronchial smooth muscle
beta 2 |
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Salmeterol MOA
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long acting beta 2 agent for prophylaxis
SE: tremor, arrhythmia |
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Theophylline
(Methylxanine) |
--likely casuses bronchodilation by inhibiting PDE, thereby v cAMP hydrolysis
--narrow therapeutic index |
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Ipratropium
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competitive block of muscarinic receptors, preventing bronchoconstriction
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Cromolyn
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prevents release of mediators from mast cells. Effective only for prophylaxis of asthma
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Beclamethasone
Prednisone |
inhibit the synthesis of virtually all cytokines
MOA: inactivate NFkB, the transcription factor that induces the production of TNF-a 1st line therapy for chronic asthma |
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Zileuton
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5 LOX pathway inhibitor
Blocks conversion of arachidonic acid to leukotrienes |
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Zafirlukast
Montelukast |
block leukotriene receptors
good for aspirin induced asthma |
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N-acetylcysteine
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Cystic Fibrosis drug
MOA: loosens mucous plugs by cleaving disulfide bonds within mucous glycoproteins |
