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52 Cards in this Set
- Front
- Back
Smells like rotten eggs, it is also used as an antidote for acetaminophen overdose to prevent liver failure.
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Mucomyst, acetylcysteine
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Break the mucoprotein bonds in mucus to help liquify secretions. increase production of resp. tract fluids & reduce
viscosity of tenacious pts. |
Mucolytics
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acetlyscyteine (Mukomyst)
Dornase alfa (rhDNAase) Guaifenesin (Robotussin) |
mucolytics
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Suppress cough reflex by a direct action on the cough center and are the most effective cough suppressants, also are narcotic
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Opiod antitussives (ex:hydrocodone, codeine)
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which antitussive is non-narcotic?
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dextromethrompone
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Aid in the removal of excess mucous that has accumulated in the resp tract by loosening & thinning secretions.
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Expectorants
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Ex of expectorants
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guiafenesin (Robitussin)
iodinated glycerol (Organidin) Potassium iodide ( Pima syrup) terpin hydrate elixir |
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Side effects of guifensin
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n/v and gastric irritation
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Pt teaching, expectorants
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Increase fluid intake to thin secrections
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What do mast cell stabilizers do?
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Prevent degranulation of mast cells after exposure to antigens; excellent prevention of allergic asthma; DO NOT relieve acute asthma attacks, may make them worse!
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How long does it take for mast cell stabilizers to have therapeutic effects?
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up to 3 weeks
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Cromolyn sodium (Intal)
Nedocomil (Tilade) |
Mast cell stabilizers (antiasthmatic agents)
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Who are mucolytic agents given to?
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Pts that have difficulty coughing up secretions such as COPD, CF, pneumonia, atelactasis, or tuberculosis
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why should mucolytics (Mucomyst, Robotussin, rhDANase) be given with a bronchodilator?
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Because they may cause bronchospasm.
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How are mucolytics administered?
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by nebulizer, direct instillation into the the trachea via ER tube or tracheotomy.
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common s.e. of mucolytics
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G.I. upset, stomatitis, rhinorrhea, bronchospasm, rash
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How long does it take for mast cell stabilizers to have therapeutic effects?
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up to 3 weeks
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Cromolyn sodium (Intal)
Nedocomil (Tilade) |
Mast cell stabilizers (antiasthmatic agents)
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Who are mucolytic agents given to?
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Pts that have difficulty coughing up secretions such as COPD, CF, pneumonia, atelactasis, or tuberculosis
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why should mucolytics (Mucomyst, Robotussin, rhDANase) be given with a bronchodilator?
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Because they may cause bronchospasm.
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How are mucolytics administered?
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by nebulizer, direct instillation into the the trachea via ER tube or tracheotomy.
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How long does it take for mast cell stabilizers to have therapeutic effects?
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up to 3 weeks
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Cromolyn sodium (Intal)
Nedocomil (Tilade) |
Mast cell stabilizers (antiasthmatic agents)
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Who are mucolytic agents given to?
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Pts that have difficulty coughing up secretions such as COPD, CF, pneumonia, atelactasis, or tuberculosis
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why should mucolytics (Mucomyst, Robotussin, rhDANase) be given with a bronchodilator?
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Because they may cause bronchospasm.
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How are mucolytics administered?
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by nebulizer, direct instillation into the the trachea via ER tube or tracheotomy.
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side effects mast cell stabilizers
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coughing, sore throat, rhinitis, bronchospasm, taste changes, dizziness, headache
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theophylline(Theo-dur, Respbid,Slo-bid)
aminophylline (Somophylin,Cardophylin dyphilline (Dilor) oxtiphylline (Choledyl) |
methylxanthines
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Relax sooth muscle of bronchial airway & pulmonary bv, resulting in bronchodilation. Indicated for symptomatic asthma relief. Chemically related to caffeine.
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Methylxanthines
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Used to control brochospasm & increase diaphragm strength in pts with COPD. Stimulates CNS, respiration. dilates coronary & pulmonary vessels, cause diuresis, relax smooth muscles
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methylxanthines
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Route of delivery for theophylline
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PO or IV
(inhalation ineffective) |
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side effects mast cell stabilizers
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coughing, sore throat, rhinitis, bronchospasm, taste changes, dizziness, headache
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theophylline(Theo-dur, Respbid,Slo-bid)
aminophylline (Somophylin,Cardophylin dyphilline (Dilor) oxtiphylline (Choledyl) |
methylxanthines
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Relax sooth muscle of bronchial airway & pulmonary bv, resulting in bronchodilation. Indicated for symptomatic asthma relief. Chemically related to caffeine.
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Methylxanthines
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Used to control brochospasm & increase diaphragm strength in pts with COPD. Stimulates CNS, respiration. dilates coronary & pulmonary vessels, cause diuresis, relax smooth muscles
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methylxanthines
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Route of delivery for theophylline
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PO or IV, rectal
(inhalation ineffective) |
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therapeutic range theophylline
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8-20 u/mL
15-20 may cause N, V & A >30 may cause cardiac dysrythmias >40 may cause seizures, death check blood levels often |
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side effects theophylline
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can cause palpitations, nervousness, restlessness, insomnia, N & V, and diarrhea.
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contraindications to methylxnathines
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drug allergy, uncontrolled cardiac arrhythmias, seizure disorders, hyperthyroid, and peptic ulcers
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client teaching methylxnathines
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limit caffeine, take as prescribed, limit smoking, drink plenty of fluids, don't take OTC cold remedies w/o checking with health care provider. monitor labs
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Primatine Mist
Sus-prine Epi-pen auto injector Isoproternol |
Catecholamine Beta agonists (sympathomimetics)
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Most commonly used Beta-2 agonist in treatment of acute asthma attacks, usually used as a rescue inhaler for bronchospasm.
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Albuterol (proventil)
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side effects of Albuterol
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tachycardia, angina, tremor, but when used correctly usually minimal.
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Only 2 long-acting Beta-2 Agonists for long term maintenance tx of asthma.
Bind selectively to beta 2 adrenergic receptors to cuase brochodialtion. take 30-60 min prior to exercise. |
Serevent Diskus (salmeterol)
Foradil Aerolizer (foradil) |
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Most commonly used Beta-2 agonist in treatment of acute asthma attacks, usually used as a rescue inhaler for bronchospasm.
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Albuterol (proventil)
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side effects of Albuterol
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tachycardia, angina, tremor, but when used correctly usually minimal.
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Only 2 long-acting Beta-2 Agonists for long term maintenance tx of asthma.
Bind selectively to beta 2 adrenergic receptors to cuase brochodialtion. take 30-60 min prior to exercise. |
Serevent Diskus (salmeterol)
Foradil Aerolizer (foradil) |
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S.E. of long-acting Beta-2 agonists
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serious side effects are uncommon. may have h/a, throat irritation, nervousness & restlessness. Can cause tachycardia so pts w/heart dz should be carefully monitored.
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epiniphrine -
nonselective or selective beta agonist? |
non-selective adrenergic.
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When given by inhalation, which are the most effective drugs available for relieving acute bronchospasm & preventing exercise induced bronchospasm.
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beta-2 agonists
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how often are long-acting beta-2 adrenergics used, what is their onset and what are the side effects?
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q 12 hr
onset delayed, but effects last up to 12 hours minimal side effect |
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Act by competing for leukotriene receptor sites, blocking inflammatory actions.
decrease edema, mucous formation, tissue constriction, inflammation. |
Anticholinergic agents
(leukotiene receptor antagonists) |