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52 Cards in this Set

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Smells like rotten eggs, it is also used as an antidote for acetaminophen overdose to prevent liver failure.
Mucomyst, acetylcysteine
Break the mucoprotein bonds in mucus to help liquify secretions. increase production of resp. tract fluids & reduce
viscosity of tenacious pts.
Mucolytics
acetlyscyteine (Mukomyst)
Dornase alfa (rhDNAase)
Guaifenesin (Robotussin)
mucolytics
Suppress cough reflex by a direct action on the cough center and are the most effective cough suppressants, also are narcotic
Opiod antitussives (ex:hydrocodone, codeine)
which antitussive is non-narcotic?
dextromethrompone
Aid in the removal of excess mucous that has accumulated in the resp tract by loosening & thinning secretions.
Expectorants
Ex of expectorants
guiafenesin (Robitussin)
iodinated glycerol (Organidin)
Potassium iodide ( Pima syrup)
terpin hydrate elixir
Side effects of guifensin
n/v and gastric irritation
Pt teaching, expectorants
Increase fluid intake to thin secrections
What do mast cell stabilizers do?
Prevent degranulation of mast cells after exposure to antigens; excellent prevention of allergic asthma; DO NOT relieve acute asthma attacks, may make them worse!
How long does it take for mast cell stabilizers to have therapeutic effects?
up to 3 weeks
Cromolyn sodium (Intal)
Nedocomil (Tilade)
Mast cell stabilizers (antiasthmatic agents)
Who are mucolytic agents given to?
Pts that have difficulty coughing up secretions such as COPD, CF, pneumonia, atelactasis, or tuberculosis
why should mucolytics (Mucomyst, Robotussin, rhDANase) be given with a bronchodilator?
Because they may cause bronchospasm.
How are mucolytics administered?
by nebulizer, direct instillation into the the trachea via ER tube or tracheotomy.
common s.e. of mucolytics
G.I. upset, stomatitis, rhinorrhea, bronchospasm, rash
How long does it take for mast cell stabilizers to have therapeutic effects?
up to 3 weeks
Cromolyn sodium (Intal)
Nedocomil (Tilade)
Mast cell stabilizers (antiasthmatic agents)
Who are mucolytic agents given to?
Pts that have difficulty coughing up secretions such as COPD, CF, pneumonia, atelactasis, or tuberculosis
why should mucolytics (Mucomyst, Robotussin, rhDANase) be given with a bronchodilator?
Because they may cause bronchospasm.
How are mucolytics administered?
by nebulizer, direct instillation into the the trachea via ER tube or tracheotomy.
How long does it take for mast cell stabilizers to have therapeutic effects?
up to 3 weeks
Cromolyn sodium (Intal)
Nedocomil (Tilade)
Mast cell stabilizers (antiasthmatic agents)
Who are mucolytic agents given to?
Pts that have difficulty coughing up secretions such as COPD, CF, pneumonia, atelactasis, or tuberculosis
why should mucolytics (Mucomyst, Robotussin, rhDANase) be given with a bronchodilator?
Because they may cause bronchospasm.
How are mucolytics administered?
by nebulizer, direct instillation into the the trachea via ER tube or tracheotomy.
side effects mast cell stabilizers
coughing, sore throat, rhinitis, bronchospasm, taste changes, dizziness, headache
theophylline(Theo-dur, Respbid,Slo-bid)
aminophylline (Somophylin,Cardophylin
dyphilline (Dilor)
oxtiphylline (Choledyl)
methylxanthines
Relax sooth muscle of bronchial airway & pulmonary bv, resulting in bronchodilation. Indicated for symptomatic asthma relief. Chemically related to caffeine.
Methylxanthines
Used to control brochospasm & increase diaphragm strength in pts with COPD. Stimulates CNS, respiration. dilates coronary & pulmonary vessels, cause diuresis, relax smooth muscles
methylxanthines
Route of delivery for theophylline
PO or IV
(inhalation ineffective)
side effects mast cell stabilizers
coughing, sore throat, rhinitis, bronchospasm, taste changes, dizziness, headache
theophylline(Theo-dur, Respbid,Slo-bid)
aminophylline (Somophylin,Cardophylin
dyphilline (Dilor)
oxtiphylline (Choledyl)
methylxanthines
Relax sooth muscle of bronchial airway & pulmonary bv, resulting in bronchodilation. Indicated for symptomatic asthma relief. Chemically related to caffeine.
Methylxanthines
Used to control brochospasm & increase diaphragm strength in pts with COPD. Stimulates CNS, respiration. dilates coronary & pulmonary vessels, cause diuresis, relax smooth muscles
methylxanthines
Route of delivery for theophylline
PO or IV, rectal
(inhalation ineffective)
therapeutic range theophylline
8-20 u/mL
15-20 may cause N, V & A
>30 may cause cardiac dysrythmias
>40 may cause seizures, death
check blood levels often
side effects theophylline
can cause palpitations, nervousness, restlessness, insomnia, N & V, and diarrhea.
contraindications to methylxnathines
drug allergy, uncontrolled cardiac arrhythmias, seizure disorders, hyperthyroid, and peptic ulcers
client teaching methylxnathines
limit caffeine, take as prescribed, limit smoking, drink plenty of fluids, don't take OTC cold remedies w/o checking with health care provider. monitor labs
Primatine Mist
Sus-prine
Epi-pen auto injector
Isoproternol
Catecholamine Beta agonists (sympathomimetics)
Most commonly used Beta-2 agonist in treatment of acute asthma attacks, usually used as a rescue inhaler for bronchospasm.
Albuterol (proventil)
side effects of Albuterol
tachycardia, angina, tremor, but when used correctly usually minimal.
Only 2 long-acting Beta-2 Agonists for long term maintenance tx of asthma.
Bind selectively to beta 2 adrenergic receptors to cuase brochodialtion. take 30-60 min prior to exercise.
Serevent Diskus (salmeterol)
Foradil Aerolizer (foradil)
Most commonly used Beta-2 agonist in treatment of acute asthma attacks, usually used as a rescue inhaler for bronchospasm.
Albuterol (proventil)
side effects of Albuterol
tachycardia, angina, tremor, but when used correctly usually minimal.
Only 2 long-acting Beta-2 Agonists for long term maintenance tx of asthma.
Bind selectively to beta 2 adrenergic receptors to cuase brochodialtion. take 30-60 min prior to exercise.
Serevent Diskus (salmeterol)
Foradil Aerolizer (foradil)
S.E. of long-acting Beta-2 agonists
serious side effects are uncommon. may have h/a, throat irritation, nervousness & restlessness. Can cause tachycardia so pts w/heart dz should be carefully monitored.
epiniphrine -
nonselective or selective beta agonist?
non-selective adrenergic.
When given by inhalation, which are the most effective drugs available for relieving acute bronchospasm & preventing exercise induced bronchospasm.
beta-2 agonists
how often are long-acting beta-2 adrenergics used, what is their onset and what are the side effects?
q 12 hr
onset delayed, but effects last up to 12 hours
minimal side effect
Act by competing for leukotriene receptor sites, blocking inflammatory actions.
decrease edema, mucous formation, tissue constriction, inflammation.
Anticholinergic agents
(leukotiene receptor antagonists)