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20 Cards in this Set

  • Front
  • Back
what are the contents for nasal fossae?
epithelium:
stratified squamous, dry in vestibule (opening of the nasal septum)
ciliated pseduostratified columnar- called olfactory epithelium in superior nasal concha (shelf like bony projection; look like folds in nasal cavity) b/c it has 3 kinds of cells (supporting cells, basal cells,& olfactory cells)

goblet cells: lots generally (but in olfactory epithelium none)

glands: mixed & abundant

cartilage: generally none (but nasal septum has hyaline)

smooth muscle: none

elastic fibers: none
what are the contents of nasopharynx?
epithelium: ciliated pseudostratified columnar

goblet cells: lots

glands: mixed & abundant

cartilage: none

smooth muscles: none

elastic fibers: present
what are the contents of larynx ?
epithelium: ciliated pseudostratified columnar (base of epiglottis, false vocal cords & just below the true vocal cords)

stratified squamous (anterior surface of epiglottis & 1/2 of posterior surface of larynx, true vocal cords)

goblet cells: lots

glands: mixed & lots

smooth muscle: none

elastic fibers: lots
where do you see changes from typical respiratory epithelium?
nasal vestibule (keritinized stratified squamous)

superior nasal concha (olfactory epithelium - pseudostratified epithelium w/ supporting cells, basal cells, & olfactory cells)

anterior surface of epiglottis, upper 1/2 of posterior surface of larynx, true vocal cords (stratified squamous;wet)

terminal bronchioles (ciliated simple columnar)

respiratory bronchioles (ciliated simpe cuboidal)

alveolar ducts (simple squamous)

alveoli (simple squamous)
What are the contents of the trachea?
epithelium: ciliated pseudostratified epithelium

goblet cells: lots

glands: mixed & present

Cartilage: c-shaped rings of hyaline cartilage

smooth muscle: (spanning open ends of c-shaped rings- trachealis m.)

elastic fibers: present
Are there specialized cells in trachea?
yes,

basal cells-form single layer against basal lamina, capable of differentiating into supporting cells

goblet cells-synthesize & secret mucus

DNES cells- diffuse neuroendocrine cells, contain small & dense core granules containing hormones (serotonin, dopamine, bombesin, calcitonin, enkephalin, somatostatin)

brush-have blunt microvilli

ciliated-sweep mucus upward which traps inhaled dust; tall columnar cells w/ cilia that project into the mucus covering the epithelium
Are there specialized cells in nasal cavitry? (specifically the superior nasal concha?)
yes,

supporting cells-attach & support sensory cells or olfactory cells

basal cells: form single layer against basal lamina that can differentiate into supporting cells

olfactory cells: bipolar nerve cells

brush cells: receptors for CN V; have short microvilli

DNES cells diffuse neuroendocrine cells, contain small & dense core granules containing hormones (serotonin, dopamine, bombesin, calcitonin, enkephalin, somatostatin)
what is metaplasia?
Change from one type of fully
differentiated adult cell type to a different type of fully differentiated cell type (epithelium) due to changes in the character of the respiratory epithelium in order to compensate for physical stress and insult; however, the change hinders the effective functionality of the epithelium,

(i,e.- smokers - cilia on ciliated cells lose their synchronous beating pattern as a result of noxious elements in smoke. as a result, removal of mucus impaired. to compensate, individual begins to cough, facilitating expulsion of mucus in airway. over time, number of ciliated cells decreases b/c of chronic coughing. this reduction in ciliated cells further impairs the normal epithelium & results in its replacement with stratified epithelium
what are the contents of the large bronchi?
epithelium; typical respiratory

goblet cells: present

glands: mixed & present

cartilage: irregular rings of hyaline

smooth muscle: crisscrossing spiral bundles

elastic fibers: lots
what are the contents of small bronchi?
epithelium: typical respiratory epithelium

goblet cells: few

glands: few

cartilage: plates & islands of hyaline

smooth muscle: crisscrossing spiral bundles

elastic fibers: abundant
what are the contents of regular bronchioles
epithelium: ciliated pseudostraitified columnar

goblet cells: scattered

glands: none

cartilage: none

smooth muscle: crisscrossing spiral bundles

elastic fibers: abundant
are there specialized cells in regular bronchioles?
yes, clara cells - perform function of goblet cells, secrete protein that protects the bronchiole lining & plays a role analogous to that of surfactant lining the alveoli
are there specialized cells in terminal bronchioles?
yes, clara cells - perform function of goblet cells, secrete protein that protects the bronchiole lining & plays a role analogous to that of surfactant lining the alveoli
are there specialized cells in respiratory bronchioles?
yes, clara cells - perform function of goblet cells, secrete protein that protects the bronchiole lining & plays a role analogous to that of surfactant lining the alveoli
what are the contents of terminal bronchi?
epithelium: ciliated simple columnar

goblet cells: none

glands: none

cartilage: none

smooth muscle: crisscrossing spiral bundles

elastic fibers: abundant
what are the contents of respiratory bronchi?
epithelium: ciliated simple cuboidal

the rest of the contents are the same as those of terminal bronchi
what are the contents of alveolar ducts
epithelium: simple squamous consisting of type I alveolar (type I pneumocyte or squamous alveolar cell) and type II alveolar cell (type II pneumocyte or great alveolar cell)

goblet cells: none

glands: none

cartilage: none

smooth muscle: at alveolar opening

elastic fibers: present
are there specialized cells in alveolar ducts?
yes,

type I pneumocytes-make up 97% of alveolar surface but low in numbers, united to ea. other through occluding junctions & desmosomes; these cells are not capable of cell division

type II pneumocytes-are secretory cells, are cuboidal or rounded found in groups of 2 or 3, have characteristic foamy cytoplasm, have prominent golgi & rER, lamellar bodies (containgin surfactant) are discharged by merrocrine mode

alveolar macrophages: derived from monocytes, phagocytize RBC's during congestive heart failure & are called heart failure cells which contain iron pigment or hemosiderin, form the first line of defense in lungs, have high specific activity of acid phosphatase, beta-glucuronidase & lysozyme
are there specialized cells in alveolar sacs?
yes,

type I pneumocytes-make up 97% of alveolar surface but low in numbers, united to ea. other through occluding junctions & desmosomes; these cells are not capable of cell division

type II pneumocytes-are secretory cells, are cuboidal or rounded found in groups of 2 or 3, have characteristic foamy cytoplasm, have prominent golgi & rER, lamellar bodies (containgin surfactant) are discharged by merrocrine mode

alveolar macrophages: derived from monocytes, phagocytize RBC's during congestive heart failure & are called heart failure cells which contain iron pigment or hemosiderin, form the first line of defense in lungs, have high specific activity of acid phosphatase, beta-glucuronidase & lysozyme
what are the contents of alveoli
epithelium: simple squamous composed of type I and type II pneumocytes

goblet cells: none

glands: none

cartilage: none

elastic fibers: yes @ alveolar openings
alveolar wall has collagen, elastin, & reticular fibers