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26 Cards in this Set
- Front
- Back
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Diphtheria
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Corynebacterium diptheriae
-Gram + -Irregularly shaped rod |
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Whooping Cough
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Bordetella pertussis
-Gram - -Coccobacillus |
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Tuberculosis
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Mycobacterium tuberculosis
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Pneumococcal pneumonia
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Streptococcus pneumoniae
-Gram + -Diplococci |
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4 Atypical pnuemonias
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-Mycoplasma pneumoniae
-Chlamydia psitacci -Coxiella burnetii -Legionella pneumophila |
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Primary atypical pneumonia
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Mycoplama pneumoniae
-no cell wall -grows in trachea -transmitted via repiratory droplets -Headache, low grade fever, and dry cough |
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Chlamydial Pneumonia, Ornithosis, Pittacosis, or Parrot Fever
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Chlamydia psitacci
-simple c/ complex life cycle -causes mental confusion, shortness of breath, flu-like sx -Exposure to sick birds |
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Q Fever
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Coxiella burnetii
-rickettsia family -contracted by tick/inhalation of feces -affects persons raising cattle/sheep |
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Legionellosis
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Legionella pneumophila
-Gram -, bacillus -multiplies intracellulary -found in natural/water supplies -15-20% mortality; acute illness 2-10 days |
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4 Respiratory Fungal Pathogens
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-Histoplasma capsulatum
-Coccidioides immitis -Blastomyces dermatitidis -Pneumocystis carinii |
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Histoplasmosis
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Histoplasma capsulatum
-most common -dimorphic -flu-like illness |
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Coccidioidomycosis
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Coccidioides immitis
-dimorphic fungi -no vaccine -semiarid climates (Joaquin V) |
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Blastomycosis
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Blastomyces dermatitidis
-dimorphic fungi -resembles TB, wart like lesions |
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Pneumocystic pneumonia (PCP)
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Pneumocystis carinii
-cysts in lungs -AIDS associated; most common death |
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Anthrax
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Bacillus anthracis
-Gram +, spore forming rod -Woolsorter's disease -Spores inhal.->ingested m0->enter bloodstream->toxin |
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Which bacterial gene encodes the toxin for Corynebacyterium diphtheria?
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tox gene
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What is a pseudomembrane?
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aids in attachment to respiratory tissues
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What is the incidence of diphtheria in the US? How is the disease prevented?
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-100,000 children in US
-It is prevented by an acellular diptheria toxoid that has been inactivated by tx c/ formaldehyde. |
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Is there a vaccine for Whooping cough?
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Yes, an acellular vaccine (included in DPT)
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What is the normal progression of Mycobacterium tuberculosis?
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Inflammation/lesions in lung tissus, causes a cellular immune response, and the growth rate is slow. Sx vary, but usually primary lesions.
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What organisms can typically causes pneumonia?
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Streptococcus pnuemoniae; S. aureus, H. influenzae, Klebsiella spp, E. coli, Proteus spp.
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What is the most common respiratory disease caused by a fungus?
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Histoplasmosis (Histoplasma capsulatum), which usually occurs worldwide and common in midwestern states.
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What is the most common cause of death among people with AIDS?
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Pneumoncystic pneumonia (PCP; Pneumocystic carinii)
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What is the pathogenesis of Anthrax?
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Spores inhaled, ingested by mO but are not killed, enter blood stream and produce toxin
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What is the tx for Anthrax?
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Ciprofloxacin
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Describe the actions of the anthrax toxin
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2 subunits: A, which contains the subunits Edema and Lethal Factors; and B, which is a protective antigen. At the cell surface, assembly occurs, forming holotoxin.
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