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40 Cards in this Set

  • Front
  • Back
Lung Cancer
#1 cancer killer of men and women
Primarily affects pts. 60-70 yr old
5% under age 40
Cigarette smoke is #1 cause
Adenogin carcinoma is most common
Where does lung cancer like to metastasize?
Liver, bone, brain and in adrenal glands. May do a PET scan to detect sites.
Pathophysiology of lung cancer
Arise from a single transformed epithelial cell in the tracheobronchial tree (airway)- the carcinogen material attaches itself to the cell and causes that transformation in the DNA of the cell and turns off at automatic stop order, typical and then we have increase in the number of cells. (hyperplasia) This is term we use for cancer cells, so we have hyperplasia of the tissues.
Hyperplasia
Increased NUMBER of cells
Hypertrophy
Increase in the size of EXISTING cells.
Small cell ( classification of lung cancer)
15-20% of tumors
Spreads quickly, fast- growing
Arises from major bronchi and spreads along bronchial walls.
They are called bronchogenic tumors=starts in major branches of bronchial tree
Lots of secretions, blood tinge sputum
Non-small cell (classification of lung cancer)
80-85% of tumors
metastasizes easier
Rises in peripheral masses or nodules into lung field
Looks like snowball on CXR
Most are adenocarcinoma, some may be squamous cells
May have persistent cough for years
Risk factors of Lung Cancer
Smoking #1
2nd hand smoke
Environmental-Radon #1, industrial carcinogens, arsenic
Genetic predisposition
Clinical Manifestations of lung cancer
#1 = cough or change in chronic cough
Hemoptysis-blood tinge sputum
Dry, persistent cough
20% have wheezing
Diagnostics of lung cancer
CXR- cotton ball effect (non-small cell)
CT scan- identify small nodules
Sputum- rarely diagnostic
Definitive Diagnosis
Fine needle aspiration and biopsy for non- small cell.

Bronchoscopy for small cell.
Medical management of lung cancer
Surgery is #1 choice- to excise tumor, lobe or whole lung. (pneumonectomy)Radiation- Done pre-op to decrease size of tumor
Chemotherapy- can cause pneumonitis, used to decrease size.
Palliative therapy- help with pain, decrease stress on other organs.
Nursing Management of lung caner
Relieve breathing problems
Deal w/ n/v assoc with chemo and radiation
Turn, cough, deep breath
Suctioning
Humidified oxygen
Chest physiotherapy
Bronchodilators- albuterol
Reduce fatigue
Lots of psychological support
What are complications of radiation?
Collateral damage of pulmonary fibrosis- destroys other lung tissue and turns it into scar tissue; pericarditis (corpulmonale) a loss of right ventricular function because of lung pathology. ARDS can cause corpulmonale by increasing pulmonary artery pressures and cause right sided failure.
Definition of Pulmonary Embolism
Obstruction of a section of pulmonary artery or one of its branches by a thrombus, comes from right side of heart.
Usually start in lower extremity
Risk Factors of PE
Venous stasis- slowing of blood flow in vein (prolonged sitting)
Hypercoagulability- due to release of tissue thromboplastin; injury, tumor, increased platelet ct
Venous Endothelial- thrombophlebitis, vascular disease, foreign bodies
Certain disease states- ht disease, trauma, postop
Other predisposing conditions of PE
age, obesity, pregnancy, oral contraceptive use, hx of previous thrombophlebitis, constrictive clothing, varicose veins, spinal cord injuries, COPD, diabetes
Patho of Pulmonary Embolism
Increased platelet clumping on valves in deep veins.
Clot forms
small piece of clot breaks off
moves through right side of ht
occludes pulmonary artery or its branches
More Patho of PE
If thrombus obstructs pulm artery we have alveolar dead space(no perfusion around alveolar)
Air is getting into alveoli sac but no blood to get oxygen in to, so problem with perfusion.
The area thats ventilated receives little or no blood flow then gas exchg is impaired.
All depends on how big clot as to how much lung capacity is diminished
Rt side has to work harder to pump blood against embolism
Cor pulmonale
failure of rt ventricle due to lung issues
Clinical Manifestations of PE
Most frequent symptom is dyspnea
" " sign is tachypnea
Chest pain- sudden onset
Tachycardia
SOA, Anxiety, apprehension
low grade fever
impending sense of doom
Diagnostics of PE
D-dimer tells if pt is at risk for developing blood clot
CAT scan
V/Q scan
pulmonary angiography
EKG
venous dopplers
Medical management of Emergency situation of PE
Anti-coag immediately, heparin drip
Thrombolytics if w/in 6hr - into rt side of ht
Surgery- throbectomy done if large clots cut off circulation
IVC filter collects clots- surgical procedure, like an umbrella, expands and catches clots. Done on venous side of vena cava
Nursing management of PE
Active ROM, early ambulation
watch for signs of DVT; unilateral swelling, redness,warm
Patent airway, use incentive spirometer
Medication is heparin #1, narcotic analgesics for chest pain.
Discharge instructions for PE
Target INR=2.0-3.0 for PE, will need to ck 1x/ wk then q 2wks as it stabilizes
No dangling legs, constrictive clothing
How to prevent and report DVT and PE
Be able to describe these things;
Underlying process
Need for continued anticoagulant therapy,
SE of coagulation like bruising/bleeding ie. no sharps, no aspirin while on warfarin, avoid laxatives (effects vit k), report dark tarry stools
S/S of lower extremity compromise such as swelling or calf pain
When to contact HC provider
Ways to prevent PE; no legs crossed, drink fluids to avoid hemoconcentration esp. in warm weather, wear stockings
Oxygen Therapy
Changes in respiratory rate or pattern:
Hypoxemia= low O2 sat of blood
Hypoxia= low O2 at tissue level ( poor gas exchange, cardiovascular disease)
Types of Hypoxia
Hypoxemic hypoxia- dec. O2 level in blood resulting in dec. O2 diffusion in tissues. Causes are hypoventilation, high altitiudes, PE, atelectasis.
Circulatory hypoxia- resulting in inadequate capillary circulation. Caused by dec. cardiac ouput, shock, cardiac arrest.
Annemic Hypoxia- decrease in hemoglobin concentration.
Histotoxic hypoxia- toxc substance like cyanide, interferes with tissues ability to use oxygen.
Oxygen Toxicity
occurs when to high a concentration of oxygen (greater than 50% is administered for longer than 48hr.

*** Restlessness, substernal discomfort and fatigue
2hr on 100%
6hr on 80%
48 hr on 50%
Oxygen devices
Low flow- contribute ox to room air
>Cannula 1-2L- mucosal drying
>Oropharyngeal catheter 1-6 L chg frequently to alternate nostril
>Mask, simple 6-8 L
>Mask, partial rebreather 8-11
>Mask, non-rebreather 12L- pt will suffocate if you put to low of air on them
High flow- deliver total amt of inspired air
>Transtracheal cath 1/4-4L req. surgical intervention and regular cleaning
>Mask, venturi 4-6L*** most accurate
>Mask, aerosol 8-10L
>Trach collar 8-10L
>T-piece 8-10L
>Face tent 8-10L
Negative Pressure Ventilators
Adjust the neg and pos pressure and the volume controls how much ventilatory effort. Machine can provide some or all.
Can adjust how much lung is inflated
Positive pressure Ventilators
inflates lungs by excerting pos pressure on the airway, pushing air in, forcing alveoli to expand during inspiration
Volume Control ventilators
Control- every respiration is provided by the ventilator
volume control- mainly use
Assist control- detects if certain amt of time has gone between resp, it will assist
SIMV- synchronized intermittent mandatory ventilation, synchronized and helps with own resp.
PEEP- positive and expiratory pressure, can use less supplemental oxygen
CPAP-continuous pos. airway pressure.
CPAP
Gas exchg. takes place during first third of expiration. Same thing as pursed lip breathing. Slows down pressure and increased expiration to provide gas exchg. Keeps alveoli sacs open.
Endotracheal Intubation
Nasal or oral
soft cuff- inflates to create a seal, occludes trachea and becomes airway
Prevents tracheal necrosis
Prevents aspiration
Tracheostomy- cuffed, fenestrated or cuffless
Care of endotracheal intubation
Daily cleaning- sterile in hospital, clean technique at home
Change ties daily
Place new ties before removing old ones
Nursing Process for ventilated pt.
>Alarms on at all times
>Empty tubing of accumulated water
>Enhance gas exchg. by positioning, turning, incentive spirometer, ABG's
>Promote airway clearance- humidified air to thin secretions.
>prevent infection
>Communication
>monitor cardiac function
>Mobility- ROM
Nutrition for ventilated pt
^ protein 25% total calories
How do you prep for weaning from ventilator
ABG's, CPAP trial, bedside pulmonary function
Complications of ventilated pts
monitor chest tubes for pneumothorax