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24 Cards in this Set
- Front
- Back
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Partial Pressure of oxygen
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PO2= Pb x Fo2= barometric pressure x fractional component of oxygen
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What causes right shift of oxygen-hemoglobin dissociation curve?
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Increased: CO2, temp, 2,3-DPG
Decreased: pH |
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What causes left shift of oxygen-hemoglobin dissociation curve?
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Increased: pH
Decreased: CO2, temp, 2,3-DPG |
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Central Chemoreceptors
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decrease in pH of brain ECF
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Peripheral chemoreceptors
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decrease in arterial PO2
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Stretch Receptors
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stretch of lungs during inflation
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Irritant Receptors
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alergen,lung inflammation, histamines
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Pulmonary C Fibers
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interstitial pulmonary edema
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Nasal, Laryngeal, and Pharyngeal Receptors
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mechanical and chemical irritants
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Jonint and Muscle Receptors
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Limb Movement
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No ventilation
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Decrease in V/Q to 0
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Normal
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V/Q is about 1
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No Perfusion
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Increase in V/Q to infinity
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Bohr Effect
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When pH of blood decrease, there is a decrease in the affinity of hemoglobin for oxygen-> release of oxygen
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Haldane Effect
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The release of oxygen form the heme portion of hemoglobin increases the affinity for CO2-> pick-up CO2
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Haldane Effect
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When the pH of blood increases, there is a decrease in the affinity of hemoglobin for carbon dioxide
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Medullary Respiratory Centers
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Brainstem- generate basic rhythmic pattern
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Pontine Resp. Cntrs
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Brainstem-pneumotaxic and apneustic centers
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Pneumotaxic Center
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switch off the inspiratory neurons
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Apneustic Center
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Prevent inspiratory nerons from being switched off
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one
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modifies the activity of brainstem neurons-alters breathing
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Zone 1
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PA>Pa>Pv -> no blood flow-ventilated, not perfused
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Zone 2
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Pa>PA>Pv -> as pressure difference increases toward bottom, blood flow will increase
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Zone 3
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Pa>Pv>PA -> capillaries are permentently opened
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