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35 Cards in this Set
- Front
- Back
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natural androgens
testosterone (short & long acting) |
Testoderm, AndroGel, Androderm, Depo-Testosterone, Depotest
ind: androgen replacement therapy, palliation of female mammary cancer, male hypogonadism route: implantable pellet, gel, transdermal patch dose: short-acting: 25-30 mg 2-3 x/week long-acting: 50-400 mg q 2-4 weeks >>weight gain, HA weight gain of more than 2 lbs should be treated by physician for edema |
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natural androgens
testosterone propionate |
Testex
ind: androgen replacement therapy, male hypogonadism, palliation of female breast cancer route: inj dose: 50-400 mg q2-4weeks |
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name side effects of androgens?
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nausea, vomiting, diarrhea. may cause elevated blood levels of Ca, Na, P, K and cholesterol. hypoglycemia, pruritus, jaundice, and alteratiosn in libido. in men, breast engorgement, impotence, male pattern baldness, and acne are expected. in females who are on androgens for an extended period of time may experience amenorrhea or menstrual irregularities. hot flashes, HA, sleep disorders, increased libido, vaginitis, and masculinization are apparent: deepening of the voice (often permanent), loss of breast mass*, increased facial and body hair*, increased muscle mass*. *=may reverse when testosterone therapy ceases.
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synthetic androgen
fluoxymesterone |
Halotestin
ind: male hypogonadism, female breast cancer route: po dose: 5-20 mg qd |
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synthetic androgen
danazol |
Danocrine
ind: endometriosis and fibrocystic disease in women route: po dose: 400mg bid |
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synthetic androgen
methyltestosterone |
Oreton, Adroid-25, Testred
ind: hypogonadism, breast cancer in women route: oral and buccal tablets dose: 10-50 mg qd |
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synthetic androgen
stanozolol |
Winstrol
ind: aplastic anemia, weight gain route: po dose: 2mg tid |
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synthetic androgen
nandrolone |
Durabolin
ind: breast cancer, anemias resulting from aplastic anemia route: inj dose: 50-100 mg/week |
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antiandrogen
finasteride |
Proscar
ind: benign prostatic hypertrophy action: used to decrease the mass of an enlarged prostate gland. route: po dose: 5 mg qd **WARNING**this drug is teratogenic, use contraception, if applicable |
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antiandrogen
dutasteride |
Avodart
ind: benign prostatic hypertrophy action: used to decrease the mass of an enlarged prostate gland. route: po dose: 5 mg qd **WARNING**this drug is teratogenic, use contraception, if applicable |
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Alpha-adrenergic Blocker
terazosin |
Hytrin
ind: benign prostatic hypertrophy action: relax the smooth muscle of the prostatic tissue to reduce obstruction route: po dose: 1-10 mg qd |
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Alpha-adrenergic Blocker
tamsulosin |
Flomax
ind: benign prostatic hypertrophy action: relax the smooth muscle of the prostatic tissue to reduce obstruction route: po dose: .4mg qd |
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Alpha-adrenergic Blocker
doxazosin |
Cardura
ind: benign prostatic hypertrophy, mild hypertension action: relax the smooth muscle of the prostatic tissue to reduce obstruction route: po dose: 1 mg qid |
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name uses of estrogens in males and females?
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in females: treat hypogonadism, postpartal breast engorgement or lactation, relieve symptoms of menopause, dysmenorhea, endometriosis, dysfunctional uterine bleeding.
in men: inoperable prostate and testicular cancers, in males, estrogen treatment causes reversable feminization during estrogen treatment. |
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name side effects of estrogen treatment?
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in females: cholasma (A patchy brown or dark brown skin discoloration that usually occurs on a woman's face and may result from hormonal changes, as in pregnancy), photosensitivity, nausea, vomiting, bloating, and risk of gallbladder disease. infertility, dysmenorrhea, breast tenderness and enlargement, increased susceptibility to thromolytic disease
>>increased sense of ewell being, high levels lead to depression that may lead to psychosis. both sexes: aggrivates asthma, epilepsy, migranes, heart disease, urinary tract disease, increase symptoms of diabetes mellitus. |
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estrogen preparations
estradiol |
oral: Estrace
transdermal: Estraderm, Vivelle, Climara vaginal ring: Estring ind: menopausal symptoms, female hypogonadism dose: oral: .5 to 20 mg qd in cycles, transdermal: .05-1mg app 1x or 2x q/week, vaginal ring: change ring q 3 months |
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estrogen preparations
estradiol valerate |
Delestrogen, Gynogen-LA
ind: menopausal symptoms, female hypogonadism, prostate cancer route: inj dose: 5-20 mg q 2-4 weeks |
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estrogen preparations
estradiol cypionate |
Depo-Estradiol,
Depogen, Dura-Estrin ind: menopausal symptoms, female hypogonadism, postmenopausal osteoporosis, prostate cancer, metastatic breast cancer route: inj dose: 5-20 mg q 2-4 weeks |
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estrogen prepartions
esterified estrogen |
Estratab, Menest
ind: menopausal symptoms, female hypogonadism, breast cancer route: po dose: .3 to 1.25 mg qd |
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estrogen preparations
esterified estrogen with methyltestosterone |
Estratest
ind: menopausal symptoms, female hypogonadism, breast cancer route: po dose: 1.25 to 2.5 mg qd |
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progesterone
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progestin: the female hormone secreted from day 14 to day 28 of the menstrual cycle. it changes the secretions of the cervix, reducing uterine contractions, maintains the corpus luteum. also stimulates the development of ducts and glands in preparation for lactation, but does not cause lactation
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what are synthetic progesterones called?
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progestins or progestogens
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why are synthetic progestins or progestogens preferred over natural progesterone?
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synthetic progestin and progestogens are more effective, because they last longer in the body and are not as readily metabololized by the liver
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what are progestins used to treat?
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progestins are used to treat amenorrhea and abnormal uterine bleeding from hormone imbalances, for contraception, in combination with estrogens for HRT in menopause, and as a therapy for renal and edometrial cancer. when used to treat infertility, it causes a negative feedback.
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what are side effects of progestin therapy?
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weight gain, stomach pain, cramping, swelling of the face and legs, HA, mood swings, anxiety, weakness, rashes, acne, insomnia. menstrual changes, and breast tenderness may occur and liver dysfunction and phlebitis are more severe adverse reactions. glucose intolerance is seen in women who are prone to diabetes mellitus and fetal teratogenic effects have occured.
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progesterone
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Crinone, Gesterol
ind: amenorrhea, abn. uterine bleeding route: inj, vag. gel dose 5-10 mg qd x6-8 days for abn. uterine bleeding |
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medroxyprogesterone
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oral: Provera, Amen, Cycrin
inj: Depo-Provera ind: endometrial hyperplasia, secondary amenorrhea, abnormal uterine bleeding, (Depo-Provera: contraception) dose: 2-10 mg qd x5-10 d for amenorrhea, abn. bleeding, Depo-Provera 150 mg q 3 months as contraceptive |
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hydroxyprogesterone
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Hylutin
ind: amenorrhea, abn. uterine bleeding route: inj dose 375 mg q 4 weeks for amenorrhea, uterine bleeding |
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progesterone
norethindrone |
Micronor, Norlutin
ind: amenorrhea, abn. uterine bleeding, endometriosis, contraception, prevention of endometrial hyperplasia with estrogen therapy route: po dose: 2.5 mg to 10 mg in cycles for amnorrhea, .35 mg qd for contraception, 5 mg for prevention of endometrial hyperplasia |
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monophasic oral contraceptive
ethinyl estradiol/ norethindrone |
Loestrin, Ovcon, Brevicon, Ortho-Novum, Genora
drug concentration: the daily dose of estrogen and progestin remain constant throughout the menstrual cycle. dose: various strengths are avl, estrogen is in mcg (micrograms) and progestin in mg |
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monophasic oral contraceptive
ethinyl estradiol/ drospirenone |
Yasmin
route: po in cycle pack drug concentration: the daily dose of estrogen and progestin remain constant throughout the menstrual cycle. dose: estrogen is in mcg (micrograms) and progestin in mg |
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monophasic oral contraceptive
ethinyl estradiol/ norelgestromin |
Ortho-Evra
route: transdermal patch drug concentration: the daily dose of estrogen and progestin remain constant throughout the menstrual cycle. dose: estrogen is in mcg (micrograms) and progestin in mg |
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monophasic oral contraceptive
estinyl estradiol/ levonorgesterel |
Levlen, Nordette
drug concentration: the daily dose of estrogen and progestin remain constant throughout the menstrual cycle. dose: estrogen is in mcg (micrograms) and progestin in mg |
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monophasic oral contraceptive
estinyl estradiol/norgestrel |
Lo-Ovral, Ovral
drug concentration: the daily dose of estrogen and progestin remain constant throughout the menstrual cycle. dose: estrogen is in mcg (micrograms) and progestin in mg |
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monophasic oral contraceptive
estinyl estradiol/desogestrel |
Desogen, Ortho-Cept, Mircette
drug concentration: the daily dose of estrogen and progestin remain constant throughout the menstrual cycle. dose: estrogen is in mcg (micrograms) and progestin in mg |
