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20 Cards in this Set
- Front
- Back
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Disease: ammenorrhea, infertility, obesity, hirsutism, +/- insulin resistance
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Polycystic ovarian syndrome
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What do you expect in the hormone profile of polycystic ovarian syndrome?
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Increase LH, decreased FSH, increased testosterone
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What does polycystic ovarian syndrome increase risk of?
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Endometrial cancer
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How do you treat polycystic ovarian syndrome?
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Weight loss, OCPs, gonadotropin analogs, clomiphene, or surgery
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List the four types of ovarian cysts
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Follicular, corpus luteum, theca-lutein, chocolate
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List the four types of ovarian germ cell tumors
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Dysgerminoma, choriocarcinoma, yolk sac tumor, teratoma
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Ovarian tumor: sheets of uniform cells, association with Turner's syndrome, increase hCG
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Dysgerminoma
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Ovarian tumor: large, hyperchromatic syncytiotrophoblastic cells, increased frequency of theca-lutein cysts, tends to go to lungs but have good response to chemotherapy, increased hCG
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Choriocarcinoma (can develop in pregnancy in mother or baby)
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Where are yolk sac tumors are found? What is the tumor marker?
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Ovaries or testes, sacrococcygeal area of young children; AFP
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List the eight ovarian non-germ cell tumors
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Serous cystadenoma, serous cystadenocarcinoma, mucinous cystadenoma, mucinous cystadenocarcinoma, Brenner tumor, fibroma, granulosa cel tumor, Krukenberg tumor
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What are the risk factors of ovarian non-germ cell tumors?
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BRCA-1, HNPCC
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Ovarian tumor: generally bilateral, lined with fallopian tube-like epithelium
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Serous cystadenoma
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Ovarian tumor: generally bilateral, psammoma bodies
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Serous cystadenocarcinoma
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Ovarian tumor: multilocular cyst lined by mucus-secreting epithelium
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Mucinous cystadenoma
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Ovarian tumor: can cause pseudomyxoma peritonei
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Mucinous cystadenocarcinoma
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Ovarian tumor: looks like the bladder
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Brenner tumor
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Ovarian tumor: bundles of spindle shaped fibroblasts
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Fibroma
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What is Meig's syndrome?
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1. Ovarian fibroma; 2. Ascites; 3. Hydrothorax (typically on right side); can cause pulling sensation in groin
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Ovarian tumor: small follicles filled with eosinophilic secretions (Call-Exner bodies), precocious puberty (kids), endometrial hyperplasia or carcinoma in adults
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Granulosa cell tumor (secretes estrogen)
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Ovarian tumor: mucin-secreting signet cell adenocarcinoma
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Krukenberg tumor (GI malignancy that metastasizes to ovaries)
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