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32 Cards in this Set
- Front
- Back
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Finasteride
MOA: repro uses: |
MOA: 5-alpha inhibitor
uses: BPH, male pattern baldness |
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Flutamide
MOA: repro uses: |
MOA: blocks testosterone receptor
(nonsteroidal) uses: prostate carcinoma |
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Ketoconazole
MOA: repro uses: |
MOA: inhibits steroid syntheses
repro uses: prevent hirsutism in PCOS S/E: gynecomastia, amenorrhea |
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Spironolactone
MOA: repro uses: |
MOA: inhibits steroid syntheses
repro uses: prevent hirsutism in PCOS S/E: gynecomastia, amenorrhea |
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Rx for mom in preterm labor 2/2 polyhydramnios?
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indomethacin (stops baby from peeing)
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What is Potters syndrome?
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renal agenesis or urinary tract obstruction
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Rx for Potter's syndrome?
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if baby over 24 wks gestation--> c sxn
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Rx for Prune belly syndrome?
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teach to self catheterize Q4 h
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1st choice for osteoporosis
MOA: 2nd choice for osteoporosis MOA: |
1st choice: Raloxifene
MOA: selective agonist and antogonist of estrogen receptor (SERM) 2nd choice: bisphosphonates MOA: inhibits osteoclasts |
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name the 3 SERM's
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1) clomifine
2) raloxifene 3) tamoxifene |
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what is a SERM?
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1) drug that works on estrogen receptors.
2) may only have effect on some estrogen receptors. 3) may be an antagonist at some receptors while an agonist at others |
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clomifene
uses: MOA: |
uses: anovulation
MOA: estrogen antagonist; desensitizes GnRH receptors from inhibitory affects of high estrogen (thus inducing GnRH release thus LH release thus ovulation) |
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raloxifene
uses: MOA: |
uses:
1st line for osteoporosis; prevent breast cancer in postmenopausal high risk women MOA: estrogen agonist in bone estrogen antagonist in uterus and breast |
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tamoxifene
uses: |
uses:
MOA: estrogen agonist at bone and uterus estrogen antagonist at breast |
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so both raloxifene and tamoxifene are agonist at bone and antagonists at breast. so whats the difference bw these 2?
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tamoxifene is agonist at uterus. (inc risk for uterine cancer)
raloxifene is antagonist at uterus (dec risk for uterine cancer) |
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rx for uterine fibroids
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1st line: ibuprofen, medroxyprogesterone, leuprolide
2nd line: hysterectomy or myomectomy (myomectomy if still wants kids) |
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leuprolide
MOA: uses: |
MOA: GnRH analogue; stimulates pit to make for LH/FSH until the high LH/FSH inhibits GnRH production.
uses: uterine fibroids infertility (if afterwards you add an ovulatory drug) |
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drugs that cause hyperprolactinemia
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1) anti DA drugs
-Haldol -Reglan -phenothiazines (antipsychotic) -MAO B inh 2) TCA's (dec seretonin and NE reuptake, so inc DA reuptake) 3) opiates |
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rx for chorioamnionitis
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clinda/gent
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rx for candidal vulvoganitis
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DOC: fluconazole
may add topical nystatin |
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rx for endometrial hyperpasia
1) w/o atypia 2) w/ atypia |
1) cyclic progestins (3-6 mo repeat bx)
2) cyclic progestins vs hysterectomy (depends on if wants babies); f/u of 3-6 mo hysterectomy) |
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contraceptive options for lactatine moms
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sterilization, barrier, IUD, progesterone only (preferred method)
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medicine to prevent preterm labor in women at high risk
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weekly injections of 17 alpha hydorxyprogesterone (from 20-36 wks gest)
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rx for septic abortion
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clida/gent; D&C if open cervix bc usually means products were retained
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1st line for hot flashes in menopause
2nd line |
1st line: venlafaxine (SNRI) or clonidine
2nd line: HRT |
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1st line for vaginal atrophy in menopause
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long term- estradiol vaginal ring
short term- low dose estrogen cream |
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1st line for endometriosis
other: |
1st: combination OCP's
other: leuprolide, danazol (trying to inhibit ovulation) |
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1st line treatment for adenomyosis?
other? |
1st line: NSAIDS
other: OCPs or progestins |
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1st line for hirsutism?
other? |
1st line: OCP's
other: spironolactone, finasteride, ketoconazole |
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rx for fibrocystic change
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-less caffeine, tea, chocolate
-supportive bra -primrose oil -vit E -vit B6 -danazol -progestins -bromocriptine -OCP's |
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DUB
mild: mod: severe: active bleed: hemodynamically unstable |
mild: Fe supp
mod: Fe and progestin (medroxyprogesterone ie provera) severe: estrogen active bleed: estrogen unstable or Hb < 9: D&C to stop bleeding |
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rx for uterine fibroids
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GnRH analogue (leuprolide)
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