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15 Cards in this Set

  • Front
  • Back

Gonadotropin Releasing Hormone (GnRH)

neuropeptide


source: hypothalamic surge and tonic center


male/female target: anterior pituitary (gonadotroph cells)
male/female action: release FSH and LH from anterior pituitary

Luteinizing hormone (LH)

glycoprotein


source: anterior pituitary (gonadotroph cells)


male target: testis (interstitial cells of Leydig)


female target: ovary (cells of theca interna and luteal cells)


male action: stimulates T production


female action: stimulates ovulation, formation of CL, P4 secretion

follicle-stimulating hormone (FSH)

glycoprotein


source: anterior pituitary (gonadotroph cells)


male target: testis (Sertoli cells)


female target: ovary (granulosal cells)


male action: Sertoli cell function


female function: follicular dev and E2 synthesis

Prolactin (Prl)

protein


anterior pituitary (lactotroph cells)


male target: testis and brain


female target: mammary cells, CL in some species


male action: induce maternal behavior


female action: lactation, maternal behavior, CL function in some species

oxytocin (OT)

neuropeptide


source: synthesized in the hypothal, stored in the posterior pit, synthesized by CL


male target: smooth muscle of epididymal tail, ductus deferens, and ampulla


female target: myometrium and endometrium of uterus, myoepithelial cells of mammary gland


Male action: PGF2a synthesis and pre-ejaculatory movement of spermatozoa


female action: uterine motility, promotes uterine PGF2a synthesis, milk ejection

Estradiol (E2)

steroid


source: granulosal cells of follicle, placenta, Sertoli cells of testis


male target: brain, inhibits long bone growth


female target: hypothal, entire repro tract and mammary gland


male action: sexual behavior


female action: sexual behavior, GnRH, elevated secretory activity of the entire tract, enhanced uterine motility

progesterone (P4)

steroid


source: CL and placenta


female target: uterine endometrium, mammary gland, myometrium, hypothal


female action: endometrial secretion, inhibits GnRH release, inhibits reproductive behavior, promotes maintenance of preg

testosterone (T)

steroid


source: interstitial cells of Leydig, cells of theca interna in female


male target: accessory sex glands tunica dartos of scrotum, seminiferous epithelium, skeletal muscle


female target: brain, skeletal muscle, granulosal cells


male action: anabolic growth, promotes spermatogenesis, promotes secretion of accessory sex glands


female action: substrate for E2 synthesis, abnormal masculinization

Inhibin

glycoprotein


source: granulosal cells (female), Sertoli cells (male)


target: gonadotrophs of ant pit


action: inhibits FSH secretion

Activin

glycoprotein


source: placental cells, granulosal cells, Sertoli cells


Target: gonadotrophs of ant pit


action: stimulates FSH secretion

Prostaglandin F2a (PGF2a)

prostaglandin


source: uterine endometrium, vesicular glands


male target: epididymis


female target: CL, uterine myometrium, ovulatory follicles


male action: affects metabolic activity of sperm, causes epididymal contractions


female actions: luteolysis, promotes uterine tone and contraction, ovulation

Prostaglandin E2 (PGE2)

prostaglandin


source: ovary, uterus, embryonic membranes


target: CL, oviduct


action: ovulation, stimulates CL secretion of P4

hCG

glycoprotein


source: trophoblast (chorion)


target: ovary


male target: increase growth of fetal testis


female target: facilitate production of P4 by ovary

eCG

glycoprotein


source: chorionic girdle cells


target: ovary


action: causes formation of accessory CL

placental lactogen

protein


source: placenta


target: mammary gland of dam


action: mammary stimulation of dam