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39 Cards in this Set

  • Front
  • Back
What does of monophasic causes less bloating, breast tenderness, but more breakthrough bleeding?
20mcg
What is the normal starting monophasic dose?
30-35mcg
How should the mini pill be taken?
On the first day of menses and at the same time everyday!
Norethindrone or norgestrel are what type of OC?
Mini pills (Progestin only)
___ decrease osteoclast function.
Estrogen
__ is a major secretory product of ovary.
E2
Nuva ring application is on what day?
Prior to the 5th day of menses
What natural estrogens have 1/10 the potency of estradiol (E2)
Estrone (E1) and Estriol (E3)
EE is a ___ estrogen?
synthetic
Mestranol is the ___ of EE. It is __% less potent than EE.
Prodrug, 50%
Mestranol must be converted to __ by liver for activity.
EE (Ethinyl Estradiol)
Estrogens are bound to ___ globulin or albumin in circulation.
Sex hormone binding globulin
If nuva ring is expelled >3 hours, what must be done?
Alternative methods for BC need to be taken.
How long is the median time to conceive after discontinuation of depo provera?
10 months
Lunelle differs from Depo provera because with Lunell, Fertility returns within ___.
One month
The single rod, 68mg implant may be less effective in whom?
Overweight patients.
Which IUD is good for 10 years?
Paragard
Which IUD is made of copper?
Paragard
If you missed a dose of a bcp and >24 hours have passed (2 missed doses), what should you do?
Take the last missed dose, discard other missed doses and return to normal routine.
When should menses start after taking the last active pill?
1-3 days
Emergency contraception acts by preventing ovulation, and sperm penetration. Which one is most effective?
Plan B-Progestin only (1 pill, 2 doses, 12 hours apart
The WHI, the estrogen plus progestin study showed a significant increase in breast CA, CHD, stroke and PE after 5 years. How did the results differ in estrogen along trial?
No effect on CHD, but an increased risk of stroke and DVT.
DHEA is the precursor of?
Testosterone and estrogen
DHEA is used for anti-aging effects and to ___
Improve performance
What androgen can be used for treatment of endometriosis?
Danazol
What drug is used for the treatment of tamoxifen resistant metatastic breast CA?
Fluvestrant
What drug is used to treat infertility?
Clomid
What androgen is a derivitive of 17a-ethinytestosterone used for the treatment of endometriosis, fibrocystic disease, and suppression of ovarian function?
Danazol
What type of adverse effects due androgens have on children?
Abnormal sexual maturaion, growth disturbance due to premature closing of epiphyseal plates
What is the treatment for advanced prostatic carcinoma?
Antiandrogens
What is the name of the antiandrogenic drug that is used for BPH?
Finasteride (Propecia)
Finasteride inhibits what prodrug?
5a-reductase thus decreasing formation of DHT and decreasing prostate size
Cyproteron acetate is an antiadrogen used in women for ___ and used in men for ____
Hirsuitism, and in men for paraphilia-excessive sexual drive
Flutamide, a competitive androgenic receptor antagonist, is used for the treatment of ____
Prostatic ca
The most common cause of ED in men >50 is?
Medication induced
With androgen replacement therapy, you should avoid use in whom?
Pts with prostate or breast CA
What labs should you monitor with a pt on androgen replacement therapy?
Annual DRE and PSA, lipid levels, increased risk for CV effects
What is the preferred A1 blocker for BPH?
Flomax
Flomax (Tamsulosin) in normotensive pts has no effect on BP. T/F
Why?
True; Because it is a non-selective alpha 1 blocker