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39 Cards in this Set
- Front
- Back
What does of monophasic causes less bloating, breast tenderness, but more breakthrough bleeding?
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20mcg
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What is the normal starting monophasic dose?
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30-35mcg
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How should the mini pill be taken?
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On the first day of menses and at the same time everyday!
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Norethindrone or norgestrel are what type of OC?
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Mini pills (Progestin only)
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___ decrease osteoclast function.
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Estrogen
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__ is a major secretory product of ovary.
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E2
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Nuva ring application is on what day?
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Prior to the 5th day of menses
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What natural estrogens have 1/10 the potency of estradiol (E2)
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Estrone (E1) and Estriol (E3)
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EE is a ___ estrogen?
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synthetic
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Mestranol is the ___ of EE. It is __% less potent than EE.
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Prodrug, 50%
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Mestranol must be converted to __ by liver for activity.
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EE (Ethinyl Estradiol)
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Estrogens are bound to ___ globulin or albumin in circulation.
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Sex hormone binding globulin
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If nuva ring is expelled >3 hours, what must be done?
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Alternative methods for BC need to be taken.
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How long is the median time to conceive after discontinuation of depo provera?
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10 months
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Lunelle differs from Depo provera because with Lunell, Fertility returns within ___.
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One month
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The single rod, 68mg implant may be less effective in whom?
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Overweight patients.
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Which IUD is good for 10 years?
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Paragard
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Which IUD is made of copper?
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Paragard
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If you missed a dose of a bcp and >24 hours have passed (2 missed doses), what should you do?
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Take the last missed dose, discard other missed doses and return to normal routine.
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When should menses start after taking the last active pill?
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1-3 days
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Emergency contraception acts by preventing ovulation, and sperm penetration. Which one is most effective?
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Plan B-Progestin only (1 pill, 2 doses, 12 hours apart
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The WHI, the estrogen plus progestin study showed a significant increase in breast CA, CHD, stroke and PE after 5 years. How did the results differ in estrogen along trial?
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No effect on CHD, but an increased risk of stroke and DVT.
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DHEA is the precursor of?
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Testosterone and estrogen
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DHEA is used for anti-aging effects and to ___
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Improve performance
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What androgen can be used for treatment of endometriosis?
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Danazol
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What drug is used for the treatment of tamoxifen resistant metatastic breast CA?
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Fluvestrant
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What drug is used to treat infertility?
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Clomid
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What androgen is a derivitive of 17a-ethinytestosterone used for the treatment of endometriosis, fibrocystic disease, and suppression of ovarian function?
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Danazol
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What type of adverse effects due androgens have on children?
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Abnormal sexual maturaion, growth disturbance due to premature closing of epiphyseal plates
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What is the treatment for advanced prostatic carcinoma?
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Antiandrogens
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What is the name of the antiandrogenic drug that is used for BPH?
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Finasteride (Propecia)
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Finasteride inhibits what prodrug?
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5a-reductase thus decreasing formation of DHT and decreasing prostate size
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Cyproteron acetate is an antiadrogen used in women for ___ and used in men for ____
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Hirsuitism, and in men for paraphilia-excessive sexual drive
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Flutamide, a competitive androgenic receptor antagonist, is used for the treatment of ____
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Prostatic ca
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The most common cause of ED in men >50 is?
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Medication induced
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With androgen replacement therapy, you should avoid use in whom?
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Pts with prostate or breast CA
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What labs should you monitor with a pt on androgen replacement therapy?
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Annual DRE and PSA, lipid levels, increased risk for CV effects
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What is the preferred A1 blocker for BPH?
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Flomax
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Flomax (Tamsulosin) in normotensive pts has no effect on BP. T/F
Why? |
True; Because it is a non-selective alpha 1 blocker
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