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12 Cards in this Set

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What is hydatidiform mole?

Cystic swelling of chorionic villi and proliferation of chorionic epithelium (only trophoblast).


- Also produces bHCG


- 2 types: Compete (empty egg + 1 sperm), partial (egg + 2 sperm)



Complete or partial hydatidiform mole has a 15-20% risk of maliganant trophoblastic disease?

Complete mole.

What is the triple test?

Estimate risk of trisomies (and neural tube defects)



The Triple screen measures serum levels of


1.AFP,


2.estriol, and


3.beta-hCG,




with a 70% sensitivity and 5% false-positive rate.

What are the RFs for ectopic pregnancy?



1. PID (STI)


2. Age


3. Old IUDs


4. Previous ectopic pregnancy


- previous surgery,

What is the treatment for ectopic pregnancy?

MTX, Surgical option

There are 2 main categories of Amenorrhoea, what are some examples of Primary and Secondary?

Primary:


- Androgen insensitivity (born XY)


- Congenital


- Malnutrition (chronic disease state)




Secondary:


- Female athelete triad


- Eating disorder


- Post- OCP with depot medroxyprogesterone


- PCOS


- Post-chemo-radiation causing ovarian failure


- Hypothyroidisms



How do you diagnose menopause?

1. 12/52 absence of menses


2. 40-60 years old



What can cause premature menopause?

Damage/removal of the ovaries:


1. Surgery


2. Chemotherapy/radiation

What is the most common cause of LUTS in men? (Lower urinary tract Sx)

Benign Prostate Obstruction

Which zones/part of the prostate does BPH usually occur in? As compared to prostate malignancy?

Centrally located transitional zone of prostate and the peri-urethral glands.




Prostate cancers usually located periphery; posterior. (DRE)

What are some of the Obstructive and Overactivity Sx?

Obx:


- Hestancy


- Poor stream


- Intermittent flow


- Incomplete emptying


- Frequent voiding


- post-void dribbling


- overflow incontinence may occur as an end-stage sx




Overactivity:


- Frequency


- Nocturia


- Urgency


- Urge incontinence in severe cases



What are the 3 classes of medical therapy (pharmacological) for BPH?

1. Alpha-antagonists


: inhibition of alpha1A-receptors -> decrease outflow resistance within 48 hours (70% of men responds)


- Tamulosin (uroselective


-Prasozin (non-selective; more A/E)


-Terazosin (non-selective)




2. 5alpha-reductase inhibitor


- long-term therapy (effects only visible 3-6months later)


-inhibits conversion of testosterone to biologically active dihydrotestosterone.


-disease progression is slowed.


-prostate volume reduce 25%


-rate of acute urinary retention is reduced


-Serum PSA reduce by 50%