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86 Cards in this Set

  • Front
  • Back

Male reproduction

Testes produce sperm


Secreted sex hormones produce testosterone


Puberty (where reproduction is possible), male is able to produce and ejaculate semen

Male onset of puberty

Hypothalamus produces GnRH


GnRH stimulates FSH in the anterior pituitary which then stimulates sperm production in seminiferous tubules

GnRH

Gonadotropin releasing hormone

FSH

Follicle (sperm) stimulating hormone

LH

Luteinizing hormone, stimulates testosterone production in interstitial cells

Prepuce (foreskin)

Serves as protective

Glans (male)

Expanded tip of the penis

Corpus cavernosa (male)

Erectile tissue, fills with blood producing an erection

Corpus spongiosa (male)

Soft erectile tissue

Urethra (in male)

Carries sperm and urine (never at the same time)

Penile function

Erection is produced by trapping of blood in corpus cavernosa in response to stimulated nervous system

Prostate gland (male) *

Produces buffer to protect sperm from acidic vagina

Vas deferens (male)

Tube that carries sperm from testes to urethra

Seminal vesicle (male)*

Sacs under bladder secrete fructose prostaglandins (helps sperm move up uterus)

Ejaculatory duct

Connects vas deferens to urethra

Cowper’s gland (male)*

Secretes clear, salty mucous for lubrication and neutralizes acidic male urethra

Epididymis (male)

Coiled tube attached to outer edge of testis, where sperm complete development

Seminiferous tubules (male)

Site of sperm production

Scrotum (male)

Sacs that contains testis, made of elastic skin, temperature regulation

Spermatogenesis

Production of sperm (puberty-death)


Occurs in the seminiferous tubules, as maturation continues, sperm cells move to lumen, then to epididymis for final maturation


Sertoli cells in the seminiferous tubules nourish the sperm as they mature


Sperm production is stimulated by FSH & testosterone


Starts in testes, ends In epididymis

Female reproduction

Reproductive organs (ovaries) produce ova (eggs)


Secretion of sex hormones from ovaries produce estrogen and progesterone


Puberty (where females are able to release eggs)

Female onset of puberty

Hypothalamus produces GnRH


Anterior pituitary produces FSH (stimulates follicle in ovary) and LH (stimulates follicle release and formation of corpus luteum)

Labia (female)

Protective flaps of skin on either side of vaginal opening, majora and minora

Clitoris (female)

Packed with sensory nerves

Vagina

Connects the uterus with outside world (sperm deposition, birth canal, protection from bacterial invasion)

Cervix (female)

Muscular band that prevents fetus from delivering prematurely (dilated at birth)

Uterus (womb)

Pear shaped, where fertilized ovum embeds in endometrium (lining)

Ovary

Store and produce eggs, generally one mature ovum is produced monthly

Oviduct (Fallopian tubes)

Carrying mature ova to uterus, usually site if fertilization. Ova swept in by fimbria at open ends

Oogenesis (female)

Girls are born with all their 1 oocytes in prophase 1


Every month after puberty until menopause, a 1 oocyte continue with meiosis 1&2 to develop into a 2 oocyte


Ovulation occurs at metaphase 2


Meiosis 2 only proceeds through anaphase 2 and telophase 2 if the egg is fertilized.


Process starts in ovaries and ends in Fallopian tubes

Menstruation

Monthly discharge of blood and fluid from uterus - caused by low levels of estrogen and progesterone at end of monthly cycle

Menstruation

Monthly discharge of blood and fluid from uterus - caused by low levels of estrogen and progesterone at end of monthly cycle

Day 1-5

Shedding of endometrium


Triggered by decrease of progesterone- stimulates FSH and LH from pituitary


Corpus luteum degenerates

Day 6-13

Follicular phase

Day 14

Ovulation

Day 15-28

Luteal phase

Travel of sperm in female

Up vagina, through cervix, into uterus, into oviduct

Fertilization

Head of sperm penetrates egg plasma membrane which triggers completion of meiosis 2 in egg, sperm and egg nucleus form a zygote

Cleavage process

Zygote undergoes first mitosis division within 30h of fertilization as it travels down oviduct

Blastocyst formation * morula..

16 cells, reaches uterus 3-5 days after fertilization.


The morula fills with uterine fluid and two different groups of cells from a sphere called a blastocyst.


Inner blastocyst cells become the embryo


Outer cells (trophoblast) become chorion (which forms placenta)

Following implantation

Human chorionic gonadotropic hormone (HCG) secreted by outer cells (chorion) of blastocyst to maintain corpus luteum which maintains level of estrogen and progesterone.

Gastrulation

During week 2, blastocyst forms 3 primary germ layers (meso-, ecto-, endo-derm).


Developing embryo now called gastrula.

Gastrulation

During week 2, blastocyst forms 3 primary germ layers (meso-, ecto-, endo-derm).


Developing embryo now called gastrula.


Start of morphogenesis, cell specialization

Ectoderm *

Nervous system, epidermis

Mesoderm *

Skeleton, muscles, reproductive structures, red blood cells

Endoderm*

Lining of the digestive and respiratory systems (pancreas/ liver, etc), endocrine glands

Amnion (supportive structure)

Forms fluid filled sac that is insulation and protection against dehydration, impact, infection, temp changes

Chorion (supportive structure)

Chorion villi invade endometrium, allies for transfer of nutrients/waste material and fetal blood ; become placenta

Allantois (supportive structure)

Initial source of nutrients in first 5 weeks, forms umbilical cord

Events in first trimester (weeks 1-13)

Germ layers are formed


Movement around week 9


Heart and brain forms


Heart beat around week 10


Placenta and umbilical cord develops


Sucking reflexes

Placenta

Temporary organ that connects developing fetus to uterine wall, nutrition intake, waste elimination, and gas exchange via mother’s blood supply

Umbilical cord

Contain one vein and two arteries


Vein carries nutrients and oxygen rich blood to fetus


Two arteries return blood containing waste from fetus back to placenta, to mom

Second trimester (weeks 14-27)

By week 17, there are sucking and swallowing reflexes, identifiable gender, skin is pink.


By week 21, fetal movement, internal organs begin to mature, eyebrows/lashes/eyelids appear


By week 25, eyes occasionally open, vernix covers skin, fetus can hiccup

Third trimester (weeks 28-40)

Body mass increases, Maturing organs, Developed taste puds, fat layers formed


brain growth!, strong movements, long fingernails


Respiratory last to develop, baby is fully developed and can survive outside the mothers body

Parturition = birth

Drop in progesterone causes contractions


Cervix thins and dilate


Amniotic membrane is forced into birth canal and bursts before delivery (water breaking)

Birth hormone (relaxin)

Produced by placenta and caused ligaments in the pelvis to loosen (dilate cervix)

Birth hormone (oxytocin)

Hormone from posterior pituitary


Positive FB loop enhances strength of contractions


Synthetic oxytocin is sometimes given to start labour

Birth hormone (prostaglandins)

Released on site, triggers more contractions

Lactation

Prolactin - stimulates milk production


Oxytocin - stimulates milk release from breast, PFB

Female Infertility

Failure to ovulate


Blockage of reproductive tract (uterine swelling)


Repeated miscarriage


Absence/malformation of reproductive tract


Hormone imbalance

Male infertility

Low sperm count


Low testosterone levels or FSH levels


Poor Sperm motility


Absence/ malformation of structure

Fertility effected by STI

Can leave scar tissue that cause blockage in male or female tracts

Artificial insemination

Man donates sperm


IUI - intrauterine insemination, uses catheter to deposit sperm


Intravaginal - via syringe, inserted into vagina

In-vitro fertilization *

Hormone therapy (injection) and superovulation, stimulates ovaries to produce numerous mature follicles


Eggs extracted


Egg and spent in Petri dish, stimulated to fertilize


Zygote forms, undergoes cleavage and inserted

In-vitro fertilization *

Hormone therapy (injection) and superovulation, stimulates ovaries to produce numerous mature follicles


Eggs extracted


Egg and spent in Petri dish, stimulated to fertilize


Zygote forms, undergoes cleavage and inserted

Surrogacy

Mather and father each donate egg and sperm


IVF formed


Embryo transfer to surrogate mother

In-vitro fertilization *

Hormone therapy (injection) and superovulation, stimulates ovaries to produce numerous mature follicles


Eggs extracted


Egg and spent in Petri dish, stimulated to fertilize


Zygote forms, undergoes cleavage and inserted

Surrogacy

Mather and father each donate egg and sperm


IVF formed


Embryo transfer to surrogate mother

Chorionic Villi sampling

Pull placenta cells out to check disorders

In-vitro fertilization *

Hormone therapy (injection) and superovulation, stimulates ovaries to produce numerous mature follicles


Eggs extracted


Egg and spent in Petri dish, stimulated to fertilize


Zygote forms, undergoes cleavage and inserted

Surrogacy

Mather and father each donate egg and sperm


IVF formed


Embryo transfer to surrogate mother

Chorionic Villi sampling

Pull placenta cells out to check disorders

Amniocentesis (2nd trimester)

Pull amniotic fluid to test for disorders

Zygote

Cell formed by the union of two gametes

Gamete

Male or female haploid reproductive cell

Gonad

Organ that produces reproductive cells

Endometrium

The mucous membrane that lines the uterus and increases in thickness in the latter part of menstrual cycle

Inhibin

Hormone released from seminiferous tubules. Acts as anterior pituitary

Follicle

In female reproductive system, cell structure within the ovaries

Androgen

Male sex hormone

Corpus luteum

Yellowish gland like structure that develops from a follicle that has matured and has released its eggs

Implantation

Process of attachment of the embryo to the endometrium

Menopause

Decrease of estrogen and progesterone results in an end of menstrual cycle

Progesterone

Female sex hormone produced first by the corpus luteum of the ovary to prepare the uterus for the fertilized egg

Testosterone

Reproductive hormones produced in the testes, stimulates development of the male reproductive tract

Journey of Sperm

Seminiferous tubules (site of spermatogenesis)


collecting duct


epididymis


vas deferens


Seminal vesicle - adds fructose to increase movement,


Prostate gland - secretes buffer to combat that acidic vagina


Cowper’s gland - produces mucous


Urethra