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22 Cards in this Set
- Front
- Back
What determines the cycle length?
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Day 1 of bright red bleeding to the next time of bright red bleeding
Average is is 28 days 21-35 still within normal limits |
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What defines oligo and hypermenorrhea?
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Oligomenorrhea > 35 day cycles
Hypermenorrhea < 21 day cycles |
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biggest cause of oligomenorrhea? others? tx?
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biggest: anovulation
others: Extremes of age – teens and perimenopause Tx: Oral contraceptives Cyclic progestins (trick the body into thinking it is in withdrawal) |
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What problem can hypothyroidism cause with respect to a woman's cycle? what is important to remember about the tx?
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oligomenorrhea
Treat with thyroid hormone – clinical response won't show up for 6 – 8 weeks |
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What problem can hyperthyroidism cause with respect to a woman's cycle?
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Oligomenorrhea or hypermenorrhea
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pt has amenorrhea that is attributed to a prolactinoma...what do you do for tx? (there are 2 things to consider here)
ALSO; this had **** on her slide, but she didn't even mention it |
TSH can be elevated... so one tx:
****Treat hypothyroidism if TSH is elevated ****Treat with bromocriptine if isolated ^prolactin |
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What effects can anorexia and obesity have on cycles?
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Anorexia: Period loss
Obesity: Lots of estrogen, gets converted to testosterone-->leads to Polycystic Ovarian Syndrome |
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An overweight woman comes to the office with oligomenorrhea, acne, and hirsuitism. She comes in because she is having difficulty getting pregnant. What should you start thinking?
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Polycystic Ovarian Syndrome
Note: this can also be in normal weight women |
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Rosary beads/String of pearls=
(she said this is common for boards, not in real life, or really important for her) |
cysts arrested in development that line the peripheral of the ovary
POLYCYSTIC OVARIAN SYNDROME |
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27 year old woman trying to get pregnant has oligomenorrhea. You do an ultrasound and see slight endometrial proliferation. Why should you get a biopsy?
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this is POLYCYSTIC OVARIAN SYNDROME
it can lead to ENDOMETRIAL CANCER |
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What role does insulin resistance play in PCOS?
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Insulin like growth factor abnormally stimulates an already overestrogenized endometrium – furthers endometrial cancer risk
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Weight loss can help increase ovulation, how much do you need to lose do this?
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only 10%
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Major tx for PCOS?
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Oral contraceptives
Increase SHBG – decrease free testosterone Improves acne, hair growth, male pattern balding Empties uterus monthly – may reduce long term risk of endometrial cancer |
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This drug increases insulin sensitivity and thus can be used as a tx for PCOS. What is the drug? What is a possible side-effect that can be beneficial?
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Metformin
May aid in weight loss- they will poop their brains out |
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What is Ovarian drilling?
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allows for rupture and release of follicles by poking holes into the ovary
you do this when you see the rosary beads/pearls pattern (PCOS) |
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What is the difference between dysfunctional and abnormal bleeding?
****COMMON PIMP QUESTION: TEST CITY |
Dysfunctional uterine bleeding – physiological dysfunction (anovulation)
Abnormal uterine bleeding – anatomical abnormality (think like a polyp on the uterus or fibroids) |
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Most common reason of Abnormal uterine bleeding?
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FIBROID
remember, AUB is due to anatomical abnormality while DUB is due to physiological bleeding....aka this is AUB |
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what are the common presentations for:
Endometrial cancer? Cervical cancer? (I don't think these will be on the test, but who knows) |
Endometrial Cancer – postmenopausal bleeding
Cervical Cancer – postcoital bleeding note to remember: Endometrial Hyperplasia – precancerous |
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What are some of the tx options for DUB?
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OCP’s
Cyclic progestins Continuous progestins – includes Depo Provera (she HATES this drug, tons of side effects), Mirena IUD (she LIKES this drug but it can be expensive and have side effects) |
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you suspect a pt has DUB so you start her on an OCP. She comes back later and is still bleeding, what is going on?
***STARRED ON SLIDE |
****If the bleeding is due to an anatomical cause, it won’t respond.
so she likely has a fibroid or polyp or some ANATOMICAL cause (AUB) |
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What is Dilation and Curettage?
possible adverse effect? |
Scrape endometrium--Diagnostic test
DOES NOT TREAT ABNORMAL BLEEDING Adverse effect: Asherman’s Syndrome – amenorrhea, uterine synechiae, infertility (get tons of scarring, looks like spiderwebs, can't get preggo) |
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what treatment can help reduce flow in up to 80% of biddies?
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Endometrial ablation
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