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14 Cards in this Set
- Front
- Back
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male gametogenesis
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FSH on Sertoli
-inhibin -ABP LH on Leydig -Testosterone |
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spermeogenesis
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in seminiferous tubules
flagella, acrasome, mitochondria |
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maturation of sperm
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in epididymus
via cAMP from Ca influx motility & concentration pluse proteoglycans |
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layers of ovulated oocyte
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secondary oocyte
in metaphase 2 oocyte zona pelucida corona radiata (granulosa + hyaluronic acid) |
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capacitation
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final maturation of sperm
happens in uterus involves CFTR & HCO3 shed glycoproteins ready for invasion of ZP |
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fertilization
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sperm secretes hyaluronidase
SED on sperm binds ZP3 on ZP results in acrosome reactions |
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acrosome reactions
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calcium wave
release acrosin (penetrate ZP) integrin & fertilin to bind & fuse complete oocyte meiosis decondense sperm nuclei pronuclear fusion |
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prevention of polyspermy
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calcium wave across egg
cortical granules in egg fuse to plasma membrane ZP refractory to sperm binding Egg surface changes |
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implantation of blastocyst
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HB-EGF receptors on blastocyst
HB-EGF expressed on endomet selectin & integrins to bind LIF to mute immune rsps TGF beta to mute invasion & grow vessels |
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7-10 days
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implantation
trophoblast hCG produced |
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12 days
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syncytoTB first to invade
maternal extravasation |
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15 days
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cytoTB engulf/surround scTB
secondary vili |
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16 days
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tertiary villi formed
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17 days
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complete maturation of villi
lacunae formed |
