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17 Cards in this Set
- Front
- Back
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by how much is the risk of dying from cervical cancer reduced by annual pap smear testing?
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90%
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what are some risk factors for cervical cancer?
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early age at 1st sex
multiple sex partners smoking immunosuppression DES exposure |
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what causes cervical cancer?
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HPV (> 99% of cases)
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what type of virus is HPV (DNA, RNA, etc.)
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double stranded, circular DNA
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what are the low risk variants of HPV that cause genital warts?
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6 and 11
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what are the high risk variants of HPV that can cause cervical cancer?
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16, 18, 31, 33, 39, 45
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what are the cervical cancer screening guidelines?
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begin Pap smear at 21
women 21-29 repeat every 2 years women 30 and older w/ 3 consecutive negatives can screen q 3yrs stop after hysterectomy or > 65 or 70 yo |
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what are some possible pap smear results?
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no dysplasia
ASC-US (atypical squamous cells of undet sig) ASC-H (favor high grade) LSIL (low grade squamous intraepit lesion) HSIL (high grade SIL) AGC (atypical glandular cells) |
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what happens when you apply acetic acid to the cervix on colposcopy?
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cells dehydrate
abnormal areas look white (aceto-white) b/c of decreased glycogen |
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what happens when you apply Lugol's solution to the cervix on colposcopy?
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iodine taken up by normal cells w/ high glycogen content
non-staining cells are abnormal |
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I say koilocytes, you say __
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HPV
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what are the 5 possible bx results from colposcopy?
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Normal
Condyloma Cervical Intraepithelial Neoplasia (1-3) Adenocarcinoma in situ Cancer |
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What are some treatment options for CIN?
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observation
ablation of abnl cells dx excisional procedures hysterectomy |
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which strains of HPV does Gardisil protect against?
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6, 11, 16, 18
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which strains of HPV does Cervarix protect against?
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16, 18
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what kind of immunity is stimulated by the HPV prophylacitc vaccines?
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Humoral CD4+/MHC2
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what procedure is done for AIS?
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CKC always
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