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14 Cards in this Set

  • Front
  • Back

Estrogen


Derived from?


Functions?


Cell produced in?


Receptor type?

cholesterol


generate estrous cycle, GnRh release


granulosa


intracellular

LH


Derived from?


Functions?


Produced in?


Receptor Type?

Peptides


Activate receptors on theca/granulosa cells to make P4, surge leads to ovulation, stimulate release of testosterone (male)


AP


GPCR

FSH


Derived from


functions


produced in


receptor type

Peptide


Activate receptors on granulosa cells to make aromatase to change testosterone to estrogen, granulosa cells to secrete antrum, spermatogenesis in Sertoli cells (males)


AP


GPCR

Progesterone P4


derived from


functions


produced in


receptor type

Lipids


Gestation, inhibit GnRH, minimize uterine contraction, promote glandular secretion, increase oxytocin receptors


Theca/granulosa cells


Intracellular

PGF2-alpha


derived from


functions


produced in


receptor type

Lipids


Apoptosis of luteal cells, oxytocin release, relaxin release


Uterus


GPCR

Inhibin


Derived


functions


produced


receptor

Peptide


Prevent FSH and some GnRH release, prevent testosterone release (male)


Granulosa (female) Sertoli (male)


non-GPCR receptors

Oxytocin


function


produced


receptor

stimulate synthesis of PGF2-alpha


Dying CL


endometrial cells

GnRH


Function


produced


receptor

release of LH and FSH


hypothalamus


GPCR in AP

CG


function


produced



Temp maintain CL after implantation of embryo, activate LH receptors on CL, promote P4 and E2 synthesis by CL


Trophoblast cells

ACTH


Function


Produced

Release cortisol andparturition


Fetal AP

NO


function


produced

vasodilation of helicine arteries=tumescence


NANC neurons

Androgens


function


produced


receptor

regulate male sexual development


Leydig cells


nuclear

Testosterone


function


produced


receptor

work with FSH to promote spermatogenesis


Leydig cells


nuclear



Prolactin


function


produced


receptor

stimulates synthesis of LH receptors on Leydig cells, released in response to GnRH


AP


Non-GPCR