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30 Cards in this Set
- Front
- Back
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What does RAS stand for?
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Renin Angiotensin System
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What does RAAS stand for?
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Renin Angiotensin Aldosterone System
(aka Renin Angiotensin System) |
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Low blood pressure stimulates kidney cells called ______ to produce ______.
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juxtaglomerular
renin |
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Renin is a(n) ______.
enzyme/hormone |
enzyme
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Renin is secreted into the ______ by the ______.
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blood
kidneys |
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Renin converts ______ into ______.
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angiotensinogen
(AN-jee-oh-ten-SIN-o-jen) angiotensin I |
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Angiotensinogen is a ______ produced by the ______.
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plasma protein
liver |
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What does ACE stand for.
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angiotensin converting enzyme
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ACE is a(n) ______.
hormone/enzyme |
enzyme
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ACE converts ______ into ______ in the ______.
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angiotensin I
angiotensin II lungs |
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Where is ACE found?
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the lungs
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Angiotensin II is a(n) ______.
hormone/enzyme |
hormone
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Angiotensin II stimulates the ______ to produce ______.
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adrenal cortex
aldosterone |
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Angiotensin II, besides stimulating aldosterone production, is also a powerful ______.
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vasoconstrictor
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Aldosterone increases sodium ______ in the kidneys, and ______ follows, increasing blood pressure.
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reabsorbtion
water |
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Aldosterone is a ______corticoid.
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mineral(corticoid)
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Aldosterone increases reabsorbtion of ______.
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Na+
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Increased ______ in the extracellular fluid directly stimulates aldosterone secretion.
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K+
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The very first ACE inhibitor was called ______.
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captopril
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ACE inhibitors are primarily used in the treatment of ______ and ______.
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hypertension
CHF |
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ACE inhibitors are often combined with ______ in the control of hypertension.
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diuretics
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The RAS in general aims to ______ blood pressure.
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increase
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ACE inhibitors ______ cardiac output and cardiac index.
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increase
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ACE inhibitors ______ arteriolar resistance and ______ venous capacitance.
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lower
increase |
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ACE inhibitors lead to increased ______ (excretion of sodium in the urine).
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natriuresis
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With ACE inhibitor use, the effects of ______ are prevented, leading to decreased blood pressure.
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angiotensin II
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Follow the sequence from decreased systemic blood pressure (stimulus) to increased systemic blood pressure (effect).
(1) stimulus: decreased BP (2) ______ cells secrete ______ (3) ______ converts ______ to ______ (4) ______ converts ______ to ______ (5) ______ stimulates ______ secretion (6) ______ also directly causes ______ (7) effect: increased BP |
Answers
(1) stimulus: decreased BP (2) JUXTAGLOMERULAR cells secrete RENIN (3) RENIN converts ANGIOTENSINOGEN to ANGIOTENSIN I (4) ACE converts ANGIOTENSIN I to ANGIOTENSIN II (5) ANGIOTENSIN II stimulates ALDOSTERONE secretion (6) ANGIOTENSIN II also directly causes VASOCONSTRICTION (7) effect: increased BP |
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Name 2 popular ACE inhibitors.
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(1) Captopril
(2) Lisinopril |
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What is cardiac index?
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A formula that relates cardiac output to body surface area, thus relating heart performance to the size of the individual.
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What is cardiac index?
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A formula that relates cardiac output to body surface area, thus relating heart performance to the size of the individual.
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