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21 Cards in this Set

  • Front
  • Back
mannitol acts at?
PT
SE of mannitol
pulmonary edema, dehydration
CI of mannitol
CHF, anuria
acetazolamide acts at?
PT
MOA of acetazolamide?
carbonic anhydrase inhibitor --> NaHCO3- diuresis
which diuretic can be used for glaucoma?
acetazolamide
which diuretic can be used for altitude sickness?
acetazolamide
which diuretic causes hyperchloremic metabolic acidosis?
acetazolamide
furosemide acts at?
TALH @ Na, K, 2Cl cotransporter
which diuretic loses Ca2+?
loops
loops toxicities
OH DANG: ototox, hypoK+, dehydration, allergy (sulfa), nephritis, gout
which drug similar to furosemide but ok in sulfa allergy?
ethacrynic acid
where does HCTZ act?
DT
HCTZ toxicites
hyperGLUC: glucose, lipids, uricemia, calcemia; hypoK+ metabolic alkalosis, hypoNa+
where does spironolactone act?
CCT
MOA spironolactone?
competitive aldosterone receptor antagonist
MOA triamterene, amiloride
block Na+ channels at CCT
which diuretics cause acidemia?
carbonic anhydrase inhibitors, K sparing
which diuretics cause alkalemia?
loops, thiazides
what happens in a low K+ state when using loops or thiazides?
H+ is exchanged for Na+ instead at CCT --> alkalosis + paradoxial aciduria
which diuretic increases plasma Ca2+
thiazides