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21 Cards in this Set
- Front
- Back
mannitol acts at?
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PT
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SE of mannitol
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pulmonary edema, dehydration
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CI of mannitol
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CHF, anuria
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acetazolamide acts at?
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PT
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MOA of acetazolamide?
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carbonic anhydrase inhibitor --> NaHCO3- diuresis
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which diuretic can be used for glaucoma?
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acetazolamide
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which diuretic can be used for altitude sickness?
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acetazolamide
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which diuretic causes hyperchloremic metabolic acidosis?
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acetazolamide
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furosemide acts at?
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TALH @ Na, K, 2Cl cotransporter
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which diuretic loses Ca2+?
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loops
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loops toxicities
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OH DANG: ototox, hypoK+, dehydration, allergy (sulfa), nephritis, gout
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which drug similar to furosemide but ok in sulfa allergy?
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ethacrynic acid
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where does HCTZ act?
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DT
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HCTZ toxicites
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hyperGLUC: glucose, lipids, uricemia, calcemia; hypoK+ metabolic alkalosis, hypoNa+
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where does spironolactone act?
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CCT
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MOA spironolactone?
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competitive aldosterone receptor antagonist
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MOA triamterene, amiloride
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block Na+ channels at CCT
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which diuretics cause acidemia?
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carbonic anhydrase inhibitors, K sparing
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which diuretics cause alkalemia?
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loops, thiazides
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what happens in a low K+ state when using loops or thiazides?
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H+ is exchanged for Na+ instead at CCT --> alkalosis + paradoxial aciduria
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which diuretic increases plasma Ca2+
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thiazides
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