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13 Cards in this Set
- Front
- Back
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Polycystic Kidney Disease (PKD)
(*note: the tissue between the cysts is normal functional renal tissue) |
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PKD - upper arrow points to a cyst and the lower arrow points to a normal function tissue |
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Acute Tubular Necrosis (ATN) with cellular casts filling the tubules (arrow) |
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Tubule in ATN
- tubular epithelial cells have undergone coagulative necrosis resulting is loss of nuclei and sloughing of cell into the tubule, forming cellular casts |
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Pt's urine has macroalbuminuria :( |
Diabetic Nephropathy (DN)
- arrow points to an atrophied tubule - interstium is filled with inflammatory cells - bottom has a hyalinized/fibroic glomerulus |
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Glomerulosclerosis due to Diabetic Nephropathy
*notice the interstitial inflammation indicated by tiny blue dots of inflammatory cells |
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Nodular Glomerulosclerosis due to Diabetes
- knots of fibrosis are called "Kimmelsteil-Wilson Nodules" and are diagnostic of DN! |
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Hyaline arteriolosclerosis due to Diabetic nephropathy
- notice that the arterioles have a thickened BM filled w/ glassy pink material (hyaline) |
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Nephrosclerosis due to long-standing HTN
- Large and small arteries show hyaline arteriolosclerosis, glomeruli are fibrosed, and tubules are atrophied |
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Renal Cell Carcinoma
- clearly circumscribed mass on left |
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Renal Cell Carcinoma
- most common variant comprised of cells with abundant clear cytoplasm - due to mutation in VHL tumor suppressor gene causing an increase in growth factors (IGF1, VEGF, PDGF) |
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Taken from medulla of pt with fever, flank pain, and WBC casts in urine |
Pyelonephritis
.... that's a sh*t-ton of neutrophils in collecting duct (circled area) and interterstitium |
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Taken from cortex of pt with fever, flank pain, and WBC casts in urine |
Pyelonephritis
- interstitium, glomerulus, proximal tubules (umm.. pretty much everything) filled with neutrophils |
