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41 Cards in this Set
- Front
- Back
Proteinuria >3.5, hyperlipdemia, fatty casts, hypogammoglobinemia, hypercoaguablitiy |
Nephrotic syndrome |
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Minimal change disease is proceeded by? |
Focal segmental glomerulosclerosis |
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LM- Segmental sclerosis and hyalinosis |
Focal segmental glomerulosclerosis |
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More common in AA & Hispanics; seen in HIV infection, sickle cell, & heroin abuse |
Focal segmental glomerulosclerosis |
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LM- Diffuse capillary and GBM thickening |
Membranous nephropathy |
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IF- granular (immunce complex deposition) |
Membranous nephropathy |
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Nephrotic presentation of SLE? |
Membranous nephropathy |
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EM- "Spike and dome" apperance w/ subepithelial deposits |
Membranous nephropathy |
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EM- effacement of the foor processes |
Minimal change disease |
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Glomerular change associated with Hodgkin lymphoma causes cytokine mediated damage |
Minimal change disease |
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Most likely seen in children, responds wel to corticosteroids |
Minimal change disease |
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Nephrotic disease not associated with hypogammaglobinemia |
Minimal change disease |
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LM- congo red strain shows apple-green birefringence |
Amyloidosis |
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Nephrotic change associated with multiple myeloma, TB, rheumatoid arthritis |
Amyloidosis |
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IF- Double countor "Tram-Trak appearance" GBM splitting, mesangial proliferation |
Type I - Membranoproliferative glomerulonephritis |
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Nephrotic syndrome with subendothelial immune complexes |
Type I - Membranoproliferative glomerulonephritis |
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Intramembrnous (BGM) immune complex deposits "dense deposits" |
Type II - Membranoproliferative glomerulonephritis |
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Glomerular change associated with both nephritic and nephrotic syndromes |
Membranoproliferative glomerulonephritis |
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Associated with HBV, HCV, and subacute bacterial endocarditis |
Type I- Membranoproliferative glomerulonephritis |
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Associated with C3 nephritic factor |
Type II - Membranoproliferative glomerulonephritis |
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Eosinophilic nodular glomerulosclerosis (Kimmelstiel-Wilson lesion) |
Diabetic glomerulonephropathy |
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Inflammation process charcterized by hematuria and RBC cast in the urine. <3.5g/day protein in urine. |
Nephritic syndrome |
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LM- glomeruli enlarged and hypercellular |
Acute poststreptococcal glomerulonephritis |
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IF- "Stary sky" grannular apperane, "Lumpy bumpy" due to IgG, IgM, and C3 deposition |
Acute poststreptococcal glomerulonephritis |
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Em- subepithelial imune complexs humps |
Acute poststreptococcal glomerulonephritis |
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Acute Poststreptococcal glomerulonephritis is caused by what type of reaction? |
Type III hypersensativity |
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Characterized by crescent moon shaped fibrin and plasma proteins in Bowman's space |
Repidly progressive glomerulonephritis |
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Linear deposits due to antiboies on GBM (RPGN) asscociated with alveolar basement membrane damage |
Goodpastures syndrome |
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Asscociated with c-ANCA & pharngyeal issues & granulomas |
Wegner's granulomatosis |
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Allergic granulomatosis, eosinophilia and asthma + P-ANCA |
Churg Straus |
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p-ANCA and RPGN |
Microscopic polyangitis |
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LM- Mesangial proliferation after a URI |
IgA nephropathy (Berger disease) |
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EM- Mesangial EM complexes |
IgA nephropathy (Berger disease) |
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Henoch-Schonlein purpura in children is asscoiated with |
IgA nephropathy (Berger disease) |
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Mutation with IV collagen- thinning and splitting of basement membrane, X-linked |
Alport syndrome (Deafness, Glomerulonephritis, eye problems) |
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RBCs Casts |
Nephrotic syndrome |
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WBC casts |
pyelonephritis |
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Ratty casts "oval" |
Nephrotic syndrome |
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Granular "Muddy brown" casts |
Acute tubular necrosis |
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Waxy casts |
Advanced renal disease |
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Hyaline casts |
nonspecific (Tam Horsfall Protein) |