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41 Cards in this Set

  • Front
  • Back

Proteinuria >3.5, hyperlipdemia, fatty casts, hypogammoglobinemia, hypercoaguablitiy

Nephrotic syndrome

Minimal change disease is proceeded by?

Focal segmental glomerulosclerosis

LM- Segmental sclerosis and hyalinosis

Focal segmental glomerulosclerosis

More common in AA & Hispanics; seen in HIV infection, sickle cell, & heroin abuse

Focal segmental glomerulosclerosis

LM- Diffuse capillary and GBM thickening

Membranous nephropathy

IF- granular (immunce complex deposition)

Membranous nephropathy

Nephrotic presentation of SLE?

Membranous nephropathy

EM- "Spike and dome" apperance w/ subepithelial deposits

Membranous nephropathy

EM- effacement of the foor processes

Minimal change disease

Glomerular change associated with Hodgkin lymphoma causes cytokine mediated damage

Minimal change disease

Most likely seen in children, responds wel to corticosteroids

Minimal change disease

Nephrotic disease not associated with hypogammaglobinemia

Minimal change disease

LM- congo red strain shows apple-green birefringence

Amyloidosis

Nephrotic change associated with multiple myeloma, TB, rheumatoid arthritis

Amyloidosis

IF- Double countor "Tram-Trak appearance" GBM splitting, mesangial proliferation

Type I - Membranoproliferative glomerulonephritis

Nephrotic syndrome with subendothelial immune complexes

Type I - Membranoproliferative glomerulonephritis

Intramembrnous (BGM) immune complex deposits "dense deposits"

Type II - Membranoproliferative glomerulonephritis

Glomerular change associated with both nephritic and nephrotic syndromes

Membranoproliferative glomerulonephritis

Associated with HBV, HCV, and subacute bacterial endocarditis

Type I- Membranoproliferative glomerulonephritis

Associated with C3 nephritic factor

Type II - Membranoproliferative glomerulonephritis

Eosinophilic nodular glomerulosclerosis (Kimmelstiel-Wilson lesion)

Diabetic glomerulonephropathy

Inflammation process charcterized by hematuria and RBC cast in the urine. <3.5g/day protein in urine.

Nephritic syndrome

LM- glomeruli enlarged and hypercellular

Acute poststreptococcal glomerulonephritis

IF- "Stary sky" grannular apperane, "Lumpy bumpy" due to IgG, IgM, and C3 deposition

Acute poststreptococcal glomerulonephritis

Em- subepithelial imune complexs humps

Acute poststreptococcal glomerulonephritis

Acute Poststreptococcal glomerulonephritis is caused by what type of reaction?

Type III hypersensativity

Characterized by crescent moon shaped fibrin and plasma proteins in Bowman's space

Repidly progressive glomerulonephritis

Linear deposits due to antiboies on GBM (RPGN) asscociated with alveolar basement membrane damage

Goodpastures syndrome

Asscociated with c-ANCA & pharngyeal issues & granulomas

Wegner's granulomatosis

Allergic granulomatosis, eosinophilia and asthma + P-ANCA

Churg Straus

p-ANCA and RPGN

Microscopic polyangitis

LM- Mesangial proliferation after a URI

IgA nephropathy (Berger disease)

EM- Mesangial EM complexes

IgA nephropathy (Berger disease)

Henoch-Schonlein purpura in children is asscoiated with

IgA nephropathy (Berger disease)

Mutation with IV collagen- thinning and splitting of basement membrane, X-linked

Alport syndrome (Deafness, Glomerulonephritis, eye problems)

RBCs Casts

Nephrotic syndrome

WBC casts

pyelonephritis

Ratty casts "oval"

Nephrotic syndrome

Granular "Muddy brown" casts

Acute tubular necrosis

Waxy casts

Advanced renal disease

Hyaline casts

nonspecific (Tam Horsfall Protein)