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6 Cards in this Set
- Front
- Back
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Type II RTA common causes
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Failure of proximal tubule
* congenital (part of Fanconi, Wison's, Cystinosis) * acquired (acetazolamide. hyperPTH, myeloma) |
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Type II RTA hallmarks
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NO STONES
glycosuria, aminoaciduria, hypophosphataemia urine pH may be <5.3 (escape mechanism for HCO3-) |
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Type I RTA common causes
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Distal tubule failure
*autoimmune (Sjoegren, PBC) * HbS * obstructive uropathy * analgesics |
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Type I RTA hallmarks
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HYPOKALAEMIA
NEPHROCALCINOSIS Urine pH ALWAYS ALKALINE > 5.3 |
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Barter's syndrome
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renal sodium, potassium and chloride wasting
hyperreninic hyperaldosteroinism normal blood pressure defect in bumetanide sensitive NaK2Cl symporter in asc. loop of Henle plasma volume low despite normal BP (stimulates renin-->aldosterone) |
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ACE I and renal function important points
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acceptable rise of creatinine 10-20%
if deteriorates rapidly consider renal artery stenosis |
