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13 Cards in this Set
- Front
- Back
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Inc. P BC inc. intratubular P d/t? 2 things
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obstruction of tubule or extrarenal urinary system: result= dec. GFR
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when use vasoconst. dec. eff and afferent. Affect on GFR? RBF?
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GFR no change RBF dec.
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____ has ind. effect on GFR apart from any vasoconst or vasorelax
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RPF
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GFR/RPF=?
greater at low or high plasma flow? |
Filtration Fraction, greater at low renal plasma flow
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aff. art. const--> on Pgc on RBF? therefore ? on GFR?
Eff. art. const ONLY at mild or mod effect on Pgc and RBF? on GFR.... changes when severe? |
aff. art const: Pgc dec. Rbf dec a lil but overall dec. GFR
eff mild: Pgc inc. RPF dec. severe: Pgc inc BUT RPF dec. so much that Pgc don't matter and get DEC. GFR! |
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Through ____ body able to maintain GFR even though dec. in Perfusion P
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Angiotensin II
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RAAS Ang II const eff and aff arterioles (___ more than ____)
SNS const both aff and efferent equally |
eff more than aff.
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Autoregulation= Myogenic response and Tubuloglomerular Feedback both affect ___ arterial
both autoregulatory to prevent big changes in GFR in spite of changes in ______ |
afferent arterial, in spite chagnes in Pressure
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Tubuloglomerular Feedback: inc and dec GFR reflected as inc. and dec. in ? sensed by ?
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NaCl, Macula Densa
Paracrines from Macula Densa scoot over to aff. art. to const or dilate that vessel |
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effect ANP?
effect dopamine (low dose)? ? protective against xs vasoconst. see w/ SNS and Ang II |
ANP=aff dilation, inc both GFR and RBF, inhibit SECRETION OF RENIN
Dopamine is a vasodilation renal a. Prostaglandins protective! NOTE: ADH vasoconst BUT RBF and GFR remain constant! |
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Thick asc loop has ___ ch.? active and passive NaCl reabs.
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NKCC
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Give someone dilate aff and const eff. effect GFR, RBF and FF?
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GFR inc, RBF same, FF Inc
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lose lot blood reflex response to hypotension is RAAS inc. therefore RBF inc or dec? efect on FF?
and kidney in vol. loss try maintain ? by recover solute and water |
RBF dec. d/t const. therefore FF inc. BUT GFR about the same because....
kidney vol. loss try to maintain GFR by recover solute and water |
