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8 Cards in this Set
- Front
- Back
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where are the majority of electrolytes absorbed in the kidney? what is mostly absorbed in the loop of henle? where do loop diuretics work and what do they inhibit? major side effect |
PCT water ascending loop of henley, Na K pump decrease Ca and harmful effect on bones |
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where do thiazides work, what do they inhibit? how do they affect calcium? what hormones work on the collecting duct? |
DCT, Na Cl pump increases it, protects bones ADH and aldosterone |
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what does aldosterone usually cause? other than the typicals, what drugs cause kidney damage? what patient factor can decrease the accuracy of cockcroft gault equation? |
retention of Na and water, and decreases K cisplatin, colistimethate, cyclosporine, loops, tacroolimus low muscle mass |
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what drugs are dosed on GFR and not CrCl? if you dont have high blood pressure or diabetes, but have proteinuria, should you be on an ACE/ARB? how high can ACE/ARB increase Scr? |
Sglt2 inhibitors and metformin yes anyone, regardless of conditions, should be on an ACE/ARB if they have proteinuria up to 30% increase |
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what is the bp goal if a patient has CKD? with proteinuria? are quinolones time or concentration dependent? In CKD, what eletrolyte imbalances result in PTH release? |
140/90...130/80 concentration dependent low Ca and high Phosphate, and lack of active vitamin D cause increase of PTH which causes resorption of bones |
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what group of phosphate binders are rarely used? why? what are the first line phosphate binders? what is the benefit of sevelamer? what is the brand name? |
aluminum based, can cause alumin toxicity and dialysis dementia calcium acetate and carbonate does not alter Ca, does not contain alumin, decreases LDL renvela |
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what is a major side effect of cinacalcet/sensipar? Other than the typicals, what drugs increase K? |
hypocalcemia drospironone, bactrim, tacrolimus, canagliflozin |
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what potassium binder can be used in emergency situations? which one cannot? |
kayelexalate/sodium polystyrene patiromer/veltassa |
