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7 Cards in this Set
- Front
- Back
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Clear Cell Carcinoma
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Sporadic: Loss of 3p segment usually with loss of VHL gene
Familial: Loss of 3p with VHL Assoc. |
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Papillary Carcinoma
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Sporadic: Trisomy of 7, 17, 20 and loss of Y
Familial: Involves C-met on 7 and assoc. with BHD Syndrome |
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Chromophobe Carcinoma
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Sporadic: Loss of 1, 2, 6, 10
Familial: Assoc. with BHD (Chrom. 17) |
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Wilms Tumor
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Familial: Deletion of Chromosome 11p containing WT1 gene; Assoc. with WAGR Syndrome, Denys-Dash Syndrome and B-W Syndrome
Sporadic: Some have WT1 mutations/deletions |
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Oncocytoma
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Assoc. with BHD Syndrome
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Low Grade Papillary Urothelial Carcinoma
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Chromosome 9 p/q deletions
-Tumor Suppressor Gene p16 |
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High Grade Papillary Urothelial Carcinoma
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Chromosome 17 (w/p53), 11, 13 (w/rb), 14 deletions
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