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36 Cards in this Set
- Front
- Back
Does anything change about urine after it leaves the collecting duct?
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no
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What is the ureter's function?
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Carries urine from the renal pelvis to the bladder.
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Structure of ureter - what are 4 layers from inner->outer?
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-Lined w/ transitional epithelium over submucosal layer
-Inner longitudinal muscle layer -Outer circular muscle layer |
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What are the contractions of ureteric muscle like?
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Peristaltic contractile waves that originate from the proximal portion
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How frequent are the peristaltic waves of the ureter?
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2-6 /min
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What triggers peristaltic contraction of the ureter? (3 things)
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-Mechanical stimuli (stretch)
-Chemical stimuli -Membrane depolarization |
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Does ureteric peristalsis require innervation?
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no
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What types of nerves innervate the ureter?
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-Symp
-Parasymp -Autonomic pain fibers |
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What is the ureter pathway like as it enters the bladder?
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-Enters low/posteriorly
-Crosses obliquely through the detrussor muscle |
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What covers the uretereal orifice?
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A flaplike mucous membrane valve
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What is the function of the flaplike valve and oblique pathway of the ureter?
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Prevents urine reflux
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What are the 2 main parts of the bladder?
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-Body
-Neck |
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What is the muscle of the bladder?
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Detrusor
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How much can simultaneous contraction of the detrusor increase bladder pressure?
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40-60 mm Hg
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How long is the bladder neck? What is it made of?
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2-3 cm; composed of detrusor muscle and elastic tissue.
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What is the function of the bladder neck?
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It serves as an internal sphincter to prevent bladder emptying until it reaches a certain critical threshold.
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Primary nerve supply to the bladder:
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Pelvic nerve
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Fibers in the pelvic nerve:
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-Sensory nerves
-PNS Motor nerves |
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What do the sensory fibers of the pelvic nerve detect and how do they respond?
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Sense Stretch - initiate bladder emptying reflex.
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What muscle do the PNS motor nerves innervate?
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Detrusor
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What somatic nerves innervate the external sphincter?
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Pudendal
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What is a cystometagram?
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The pressure:volume curve for the bladder.
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What is the compliance of the bladder at low volumes?
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High
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How do you know the bladder is highly compliant at low volumes?
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Because it can hold a lot of volume with minimal changes in pressure.
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What happens as the bladder fills with volume?
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Its compliance decreases so pressure begins to increase rapidly
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What are Micturition waves?
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Periods of increased luminal pressure in the bladder that can reach up to 100 cm H2O and last seconds up to a minute.
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What are micturition waves initiated by?
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Sensation of stretch by stretch receptors in the bladder wall.
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Where does the impulse go when stretch receptors sense increasing stretch?
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To the sacral spinal cord, then back to the bladder via the PNS pelvic nerve
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What happens to the micturition waves as the bladder fills?
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They increase in frequency and strength.
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What can happen to micturition waves?
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They can cease for minutes up to an hour, but will come back!
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What happens when micturition waves become powerful enough?
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They initiate a reflex through the pudendal nerves to inhibit the external sphincter.
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What will happen when the pudendal reflex is stimulated?
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Urination - unless your voluntary control is greater.
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Is micturition completely reflex?
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No; higher cortical centers exert the final control.
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How do higher centers have the final control of micturition?
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They partially inhibit micturition reflexes by voluntary contraction of the external bladder sphincter.
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How is voluntary urination initiated?
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1. Abdominal muscles contract
2. Bladder pressure increases 3. Higher centers simultaneously stimulate micturition reflex and inhibit the external sphincter. |
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So the main function of the micturition reflex is really to:
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Empty the bladder.
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