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30 Cards in this Set

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Definition acute renal failure

Sudden reversible impairment of function, causing retention nitrogen substances, hypervolemia, electrolyte and acid base imbalance

Symptoms acute renal failure

Oligoanuria


N,v, maybe d from uremic gastritis or colitis


Fatigue exhaustion loss appetite and w


S- anxiety confusion somnolence drowsy coma

PE aki

Impaired gen, kussmaul breathing, pale skin, cold swest


Tongue yellow/brown


Bp hr depend on cause


Lab aki

Proteinuria and erythrocyteuria


Specific gravity urine


Leukkcyteuria if i fection


Osmolarity- +500mosm/l prerenal, -300 if acute tubular necrosis


High creatinine, BUN, uric acid


Hyperkalemia


Decompensated metabolic acidosis


Blood- mikd anaemia from water retention

Instrument aki

Ab ultrasound


Ecg-high t wide qrs if hyperkalemia


X ray lungs-congestion


Others for primary disease

Complications aki

Uremic coma


Pulmonary cerebral oedema


Cardiac arrest


Pericarditis


Vuln to infections

Ckd definition

Progressive irreversible impairment function reducing clearance of N and hormones rtc leading to gen intoxication misbalance electrolys and a b

Etio ckd

Chronic glomerulonephritis


Diabetes, amyloidosis, lupus


Uncontrolled hypertension

Symptoms ckd

Fatigue exhaustion headache


Muscle weakness loss w and a


Thirst nocturia


Itching from uric acid


Bone pain hypocalcemia from less vit d


Hypertension and ihd


Peripheral neuropathy


Erectile dysfunction less libido amenorrhea

PE CKD

Impaired ge, kussmaul


Reduced muscle fat and tissue


Dirty pale colour skin, dehydrated


Yellow brown tongue


Odour urine


Arterial hypertension increased hr

Lab ckd

Increased creatinine uric acid urea


Hypocalcemia hyperphosphatemia


Decompensated metabolic acidosis


Anaemia


Urine protein rbc wbc


Urine culture, specific gravity


Total protein, albumin


Increased sr alpha amylase

Instrumental ckd

Ab us nephrosclerosis- kidneys less than 9cm narroed parenchymal zone less 14 mm


Renal biopsy


Ecg echo x ray

Definition acute glomerulonephritis

Acute diffuse immune inflammation of both kidneys affecting gbm mesangium and capillary endothelium

Etio acute glomerulonephritis

Strep group a m form immune complexes on gbm and mesangium cause loval inflamm w/ stasis and prolif of endothelia and mesangial cells and infiliteation w/ leukocytes and monocytes

Symptoms acute glomerulonephritis

10-14 days after pharyngitis


Oli/anuria from reduced gfr


Hypervolemia-oedema, hypertension


Impaired clearance and reg a b electrolytedls


Fatigue exhaustion confusuon loss appetitie headache n v d w loss


Macroscopic hematuria


Tenderness lumbar region


Poss fever

Pe acute glomerulonephritis

Impaired gen


Periorbital oedema, swollen legs


Yellow brown tongue w/odour


Heart-n/bradycardia high bp

Lab acute glomerulonephritis

Increasdd wb sr crp


Urine-high specific gravity, proteinuria hematuria


Increased creatinine urea uric acid k


Increased ast

Instrumental acute glomerulonephritis

Ab us kidneys enlarged w/ diffuse structural changes


Ecg x ray, echo


Opthalmoscopy ct if suspected cerebral oedema

Complications acute glomerulonephritis

Pulm/cerebral oedema


Uremic coma


Chronic, usually mesangioprolif


Subacute glomerulonephritis

Etio subacute glomerulonephritis

Rapidly progressive autoimmune


Infection hep b/c hiv syphillis malaria

Definition chronic glomerulonephritis

Chronic progressive diffuse immune inflammations of both kidneys damaging the gbm and mesangium leading to irreversivle and progressive renal failure

Chronic membranous glomerulonephritis etio

Infections, usual


Tumors cancer lymphoma


Autoimmune dksesse


Drugs lithium mercury

Symptoms chronic membranous glomerulonephritis and diagnosis


Severe oedema from proteinuria


Malaise fatigye exhaustion


Biopsy-spur like subepithelia depositions gbm

Chronic mesangioproliferative glomerulonephritis

Arterial hypertension and hematuria


Massive haematuris moderate proteinuria


Icreased sr crp often ast


Mild iron deficiency anaemia

Nephrolithiasis stone classification

Oxalates


Uric acid


Struvite


Cystein

Predisp nephrolithiasis

Hyperuricemia-gout metabolic syndrome chronic renal failure


Cysteinuria hereditsry


Distal tubular acidosis

Symptoms nephrolithiasis

Renal colic-sudden harsh pain lumbar region props to bladder


Hematuria


N v fatigue


Pain burning urination if stone in bladder or cystitis

Lab nephrolithiasis

Urine rbc mild proteinuria


Blood count sr normal unless infection


Creatine uric acid usually n

Instrumental nephrolithiasis

Ab us


X ray roentgen positive stones oxakates phosphates cystreinq


Roentgen neg (uric acid) by venous urography


Ph urine


Chemical analyisis stones

Complications nephrolithiasis

Hydronephrosis


Infections


If both ureters obstructed urine retention aki