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10 Cards in this Set
- Front
- Back
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which side is ADPKD most seen on?
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TRICK!! its always bilateral
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What are the two types of ADPKD? What most common type?
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1. PKD1, 16p13.3, polycystin-1 = 95% have this one = MOST COMMON
2. PKD2, 4q21, polycystin-2 |
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what is the mean age of onset for ADPKD type I?
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53
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what is the mean age of onset for ADPKD type II?
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69
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with ADPKD where else will you have cysts?
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the liver
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describe the collecting tubules in ARPKD?
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all of them are dialated
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what mutation is the cause of ARPKD?
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PKHD 1 gene on 6p21-23; encodes fibrocystin
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in patients who survive ARPKD in infancy what often will develop?
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congenital hepatic fibrosis leading to portal hypertension
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even though cystic disease is usually benign, why are cysts often removed if they are caught on radiological findings?
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the look identical to cystic renal carcinomas
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where are cysts found in the kidney with cystic disease?
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in the cortex
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