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15 Cards in this Set
- Front
- Back
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how many RBCs wear out per day |
about 1% or 3 million |
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what monitors RBC recycling |
macrophages of liver, spleen, and bone marrow |
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when do macrophages engulf RBCs |
before their membranes rupture (hemolyze) |
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what is Hemoglobinuria |
too many RBCs are broken down, hemoglobin and its breakdown products are in urine |
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what is hematuria |
whole blood cells are in urine due to kidney or tissue damage |
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how is hemoglobin recycled |
phagocytes break it into its components -globular proteins into AAS -heme into biliverdin (by removing iron) |
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why do you not want large quantities of free iron |
it is toxic |
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what is iron bound to for storage a d transport (not heme) |
transferrin to transport ferritin and hemosiderin for storage in liver, muscle, and spleen |
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how is iron transported to be recycled |
transported back to bone marrow by transferrin |
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how is biliverdin broken down |
it is converted to bilirubin, which is yellow |
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what color is biliverdin |
green |
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where is bilirubin excreted |
by liver (bile) -this is why bile is a yellowish color |
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where is bilirubin converyed to urobilin |
in the intestines by intestinal bacteria |
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what happens to urobilin (reabsorption) |
it is reabsorbed into the blood and then excreted by the kidneys |
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what happens to leftover urobilin |
it is converted to stericobilin which gives poop its brown color |
