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25 Cards in this Set
- Front
- Back
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two types of muscarinic receptors? |
muscarinic and nicotinic |
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three types of adrenergic receptors? |
alpha and beta and dopamine receptors |
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how many nicotinic subtypes? |
2 Nn and Nm |
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how many muscarinic subtypes? |
5 |
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how many alpha receptors? |
2. alpha 1 and alpha 2 |
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how many beta receptors? |
3. beta 1, beta 2, beta 3 |
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what does agonizing alpha1 receptors do on CV system? |
increase peripheral vascular resistance so increase BP |
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Side effect of alpha 1 agonist on CV system? |
reflex bradycardia |
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what does alpha 2 receptors do on CV system? |
slight peripheral vasoconscrtiction mainly decrease central sympatheic outflow so decrease BP |
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What do beta 1 receptors do on CV system? |
positive inotropic, chronotropic, dromotropic so increase BP |
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what do beta 2 receptors do on CV system? |
dilate SKM blood vessels decrease vascular resistance so decrease BP |
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Side effect of beta 2 receptors? |
reflex tachycardia |
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what do nonselective beta agonist do? |
elevate HR and force of contraction |
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what receptors does norpinephrine affect?
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agonizes alpha 1 and beta 2 |
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norepinephrine effect on BP? |
increase both systolic and diastolic |
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Norepinephrine effect on HR? |
reflex bradycardia |
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what receptors does isoproterenol affect? |
agonizes beta 1, 2, 3 (little effect on beta 2) |
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effect of isoproterenol on BP? |
Decrease diastollic pressure, increase systolic pressure Significant effect on vascular resistance (B2) B1 effect on cardiac inotropy |
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effect of isoprterenol on HR? |
strong B1 effect, increases rate and force |
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what receptors does epinephrine agonize? |
alpha 1, beta 1, beta 2 |
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what adrenergic agonist must be given peripherally through IV? |
Epinephrine |
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what receptor does low dose of dopamine affect? result? |
D1 increases renal, coronary, and splanchnic BF |
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what receptor does medium dose of dopamine affect? result? |
b1 cardiostimulatory |
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what receptor does high dose of dopamine affect? result? |
alpha 1 increased peripheral resistance, decrease BP |
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what is dopamine used for? |
tx of schock, esp with low CO and renal perfusion |
