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22 Cards in this Set
- Front
- Back
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Pituitary Tumors
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Prolactin secreting
Non Secreting GH ACTH |
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women w/amenhorrea, galctorrhea
men w/ED |
prolactin secreting pituitary tumor
(inhib's est & testost) tx w/DA |
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HA, vis field deficit, decreased GH
diabetes insipidus |
hypothalamus tumor
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HA, vis field deficit, decreased GH
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non secreting pituitary tumor
tx w/surgery dx w/MRI |
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kids with gigantism
adults w/acromegally (increased hat & shoe size) elevated insulin like GF |
GH secreting pit tumor
tx w/somatostatin |
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treatment of GH secreting tumor
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somatostatin
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hypercortisol sx's w/normal adrenal gland, normal hypothalamus, normal aldosterone
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ACTH secreting pit tumor
tx w/surgery |
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Thyroid tumors
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papillary (most common, best OC)
-ground glass nodules follicular (responds like pap) medullary (worst)- calcitonin Anaplastic lymphoma |
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calcitonin is tumor marker for...
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medullary thyroid
-from cheif cells common w/MEN2 |
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thyroid tumor comon w/MEN2
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medullary
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increased Ca
"Bones, Moans & Psych Overtones" |
hyperparathyroid tumor
(80% are adenoma) can give DI b/c Ca dmg aquaporins |
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Pancreatic tumors
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endocrine= insulinemia, gastrinoma, glucagon secreting, VIP
exocrine= high mortality |
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Pancreatic endocrine tumors
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insulinoma
-eat a lot (esp late at nite) Gastrinoma -peptic ulcer dz -tx w/surgery & PPI's glucagon secreting -glucose intol -diarrhea VIP secreting -diarrhea |
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Adrenal adenomas
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cortisol secreting
-high cort, low ACTH -sx's like Cushings Aldosterone secreting -high ald, low renin -HTN & HypoK Pheochromocytoma -HTN, sweaty, tachy, palp, ortho hypo, doom -medullary pancreas MEN1 |
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HA, HTN, doom
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pheochromocytoma
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MEN 1 tumors affect
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3 P's
-pancreas (gastrin "Z-E") -pituitary (vis & GH) -parathyroid (kidney stones) kidney stones, |
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inheritance w/Men tumors
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auto dom
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MEN tumor w/kidney stone & stomach ulcer
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type I
"wermers" tumor suppressor gen mutation |
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MEN w/ongogene activated
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MEN 2 & 3 (aka 2 b)
"Sipple's" ret gene |
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MEN assoc's w/medullary thyroid and/or pheo
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MEN 2 & 3 (aka 2 b)
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MEN associated w/zollinger ellison
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MEN 1
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3 paraneoplastic syndromes
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PTH related peptide
-assoc w/squamous cell ADH secretion -assoc w/sm cell carcinoma ACTH secreting -aggressive |
